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  1. a16z36 min

    a16z Podcast | Connecting Hearts, Bodies, and Networks to Cure Cancer

    Amy Abernethy, Christina Lopes, Jorge Conde, Sonal

    Amy Abernethy has been selected as the new Principal Deputy Commissioner of the FDA, where she aims to advance personalized medicine and accelerate evidence generation following her tenure at Flatiron Health. Her appointment aligns with the growing adoption of One Health strategies, a platform co-founded by Cristina Lopez that leverages spontaneous canine cancer data to validate human therapies. By treating dogs as natural clinical models with fully functional immune systems, this initiative promises to save costs in drug development and improve outcomes for both veterinary and human patients through shared real-world evidence.

  2. a16z27 min

    a16z Podcast | Shifting Risk Mindsets, From Tech to Bio

    Vijay Pande, Jorge Conde, Jeff Low, Jeffrey Lowe

    This event guides tech founders through the critical challenges of translating their innovations into the biotechnology sector, emphasizing the necessity of treating biotech firms as data-driven enterprises. It details strategies to avoid operational pitfalls like "death by a thousand pilots" and outlines structural frameworks, such as LLC ring-fencing, to protect platform value while developing proprietary assets. Furthermore, the session provides actionable insights on diagnostics reimbursement, early validation "kill tests," and aligning hybrid investor syndicates to ensure sustainable growth in a high-barrier market.