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  1. a16z27 min

    The China Threat: Silicon Valley and the Great Uncoupling

    Mike Gallagher, Jake Auchincloss

    Representative Gallagher identifies the collapse of deterrence in the Indo-Pacific as the primary strategic threat to U.S. security, arguing that failing to mass-produce long-range precision fire systems risks a catastrophic war with China on adversarial terms. He characterizes this rivalry as an ideological contest where 90% of the challenge rests on internal American reforms regarding education, immigration, and infrastructure rather than external actions alone. Addressing specific policy failures, Gallagher advocates for a forced sale of TikTok to mitigate cyber threats, critiques the current CHIPS Act for potentially increasing Taiwan's vulnerability, and urges the Department of Defense to adopt a more experimental, failure-tolerant procurement model to drive innovation.

  2. Milken Institute44 min

    The Future of Brain Health

    Meg Tirrell, Ruth Benca, Marie Bernard, Rod Hochman, Nora Super, Rudy Tanzi

    The Milken Institute released a 2023 report highlighting the disproportionate burden of dementia on women alongside scientific breakthroughs in early detection and the re-evaluation of amyloid-targeting therapies like aducanumab. Experts are advocating for a multifactorial shift toward affordable oral medications, preventive sleep strategies, and age-friendly care systems that reduce reliance on hospital settings. While a total cure by 2025 remains unlikely, the field is converging on combining pharmacological interventions with lifestyle modifications to manage risk and improve outcomes for diverse populations.