Latest Interviews
Showing 151–165 of 1,991 transcripts.
Clear all filters- All-In Podcast45 min
John Fetterman: 'I'm the Only Democrat in Congress Saying This'
John Fetterman, David Friedberg
Senator John Fetterman positions himself as a fiscally conservative Democrat who rejects the party's progressive label and current leadership while maintaining full support for recent military strikes against Iran and strict voter ID measures. He argues for prioritizing national security over partisan loyalty, citing concerns over non-citizen voting and the need to counter China's technological rise, though he simultaneously criticizes his party's base for adopting policies that alienate working-class voters. Despite acknowledging internal party dysfunction, Fetterman remains open to a future presidential run as he seeks to bridge ideological divides on issues ranging from immigration enforcement to AI development.
- a16z47 min
Why Scale Will Not Solve AGI | Vishal Misra - The a16z Show
Researchers have mathematically validated that Large Language Models function as "Bayesian wind tunnels," where in-context learning precisely updates token probability distributions in real-time rather than relying solely on statistical correlation. Despite demonstrating this capability through the open-sourced "TokenProbe" tool and reproducing results across transformer architectures, current models remain fundamentally limited by their frozen weights and inability to perform causal reasoning or discard established axioms. Bridging the gap toward Artificial General Intelligence therefore requires a new architectural approach to implement true continual learning and move from association to simulation, as identified in recent work comparing LLM behavior to Judea Pearl's causal hierarchy.
Deel Hits $1.4B+ in ARR | CEO Alex Bouaziz Shares Growth Playbook
Alex Bouaziz, Molly O'Shea, Shuo Wang, Micky Malka
Deel, co-founded by Alex and Shuo, has grown its annual recurring revenue from $800 million to over $1.4 billion, securing a $17 billion valuation through a funding round led by Rivet Capital. This fully remote organization now serves over 40,000 global clients by providing integrated HR infrastructure across 120 countries while maintaining profitability and raising minimal external capital prior to its Series A. With a strategic focus on IPO readiness, a $100 billion valuation target, and the productization of internal AI tools, the company continues to expand its ecosystem through specialized acquisitions and brand partnerships.
- All-In Podcast1h 16m
Two Legendary Founders: Travis Kalanick & Michael Dell Live from Austin, Texas
Travis Kalanick, Michael Dell, Friedberg, Brad Gerstner
At the All-In Summit, Travis Kalanick officially ended the seven-year stealth phase of his new physical AI venture, Adams, by unveiling a platform that treats atoms like bits to revolutionize food production and mining automation. Concurrently, Michael Dell detailed the explosive growth of his AI infrastructure business and championed the bipartisan Invest America Act, a capital account initiative designed to seed $1,000 for every U.S. child to foster broad-based ownership. Both leaders emphasized a strategic pivot toward Texas as a pro-growth hub for industrial scaling while advocating for aggressive AI integration and open-source collaboration to drive future economic abundance.
- Milken Institute51 min
Advancing Economic Mobility | Future of Finance 2026
Dan Carol, Anna-Lisa Miller, Shil Patel, Rob J. Shapiro, Marcus Shaw
The event outlines a multi-pronged economic strategy combining newborn investment accounts, federal retirement matching for gig workers, and expanded worker ownership to address extreme wealth concentration. Key participants including Ownership Works and Alt Finance demonstrate how equity participation and HBCU talent pipelines generate significant returns for non-c-suite employees and underrepresented communities. By integrating these private sector innovations with policy proposals for mid-career retraining, the initiative aims to mitigate AI-driven displacement risks and secure broad-based long-term economic mobility for millions of Americans.
- All-In Podcast1h 20m
Iran War, Oil Shock, Off Ramps, AI's Revenue Explosion and PR Nightmare
Brad Gerstner, Howard Schultz, Jason Calacanis, David Sacks
The discussion centers on a dual strategy of domestic wealth redistribution through direct child equity accounts and geopolitical risk management during a volatile conflict in the Middle East that spiked oil prices and inflation. Industry leaders debate the scalability of AI revenue, contrasting production-ready utility against experimental testing, while simultaneously analyzing how "doomerism" narratives and restrictive regulations threaten data center development and profitability. Finally, the program examines the economic consequences of state-level wealth taxes on migration patterns, warning of capital flight and budget shortfalls while advocating for deregulation as a superior alternative to asset seizure.
Inside a16z Growth: Waymo, Stripe, ElevenLabs, Revolut, Coinbase, Kalshi
a16z's growth fund focuses on market leaders demonstrating extreme velocity and defensibility, exemplified by strategic investments in Waymo's autonomous scaling, 11 Labs' voice AI dominance, and Kalshi's regulatory-first prediction market. While the firm accepts currently compressed gross margins in AI sectors, it prioritizes companies with proprietary data, high retention, and clear paths to $10 billion valuations over generic growth narratives. This approach targets a "productive oligopoly" where top-tier players capture vast market share, with a future outlook projecting multiple trillionaires emerging from AI and fintech sectors within a decade.
- All-In Podcast1h 0m
They're Opening the Stock Market to Everyone. Here's What That Actually Means
Jason, Paul Atkins, Michael Selig, Chamath Palihapitiya
SEC Chair Paul Atkins and CFTC regulators outlined a comprehensive agenda to reverse the decline of public capital markets by slashing compliance burdens, redefining accredited investor status, and reducing quarterly reporting requirements. The agencies are simultaneously drafting a harmonized framework for digital assets and AI trading agents to foster innovation while establishing strict guardrails against systemic risk and predatory speculation. These reforms aim to preserve U.S. global competitiveness by balancing reduced regulatory friction for companies with enhanced protections for retail investors against emerging market hazards.
- All-In Podcast1h 3m
“This is Bibi’s War” - Harvard’s Graham Allison on the Influences and Endgame of the Iran War
Graham Allison, Chamath, Jason, Friedberg, Scott Besant
Graham Allison analyzes the current geopolitical landscape by characterizing the escalating Iran conflict as a high-risk campaign driven by Prime Minister Netanyahu's ambitions rather than imminent U.S. threats, while warning that premature regime change could trigger a chaotic power vacuum. Parallel to these Middle East dynamics, Allison assesses a low probability of immediate Chinese aggression on Taiwan due to strategic ambiguity and internal PRC vulnerabilities, even as he identifies extreme domestic wealth inequality in the United States as a primary driver of rising populist instability. The discussion further highlights the critical fragility of the non-proliferation regime and suggests that long-term security for the U.S. and its allies depends on maintaining this status quo rather than pursuing aggressive expansionist maneuvers in the Arctic or elsewhere.
- a16z51 min
Andrew Huberman: Peptides, Sleep Tech, and the End of Obesity
Professor Andrew Huberman outlined a major shift in consumer health toward proactive management driven by the pandemic, highlighting the transformative impact of GLP-1 drugs and non-GLP peptides on obesity treatment and tissue repair. The discussion detailed critical nutritional and circadian interventions, such as strategic carbohydrate timing and core-body cooling, alongside emerging AI diagnostics and "write-to-biology" technologies aimed at extending human lifespan toward one hundred years. Huberman further emphasized the need for scientific literacy amidst political polarization while predicting rapid adoption of sleep optimization devices and real-time biomarker monitoring within the next five years.
- Y Combinator53 min
The Future Of Brain-Computer Interfaces
Science co-founder Max Hodak outlines a biotechnology roadmap centered on the Prima retinal implant, which has already restored form vision to over 40 patients with macular degeneration, and predicts an imminent "takeoff era" that could enable the first 1,000-year lifespans. Beyond vision restoration, his company is developing bio-hybrid neural interfaces that integrate stem-cell-derived neurons into the brain and portable "Vessel" perfusion systems to revolutionize organ preservation and treat severe disabilities like glaucoma. These initiatives aim to shift healthcare from slow drug discovery to precise neural engineering, potentially achieving high-bandwidth human-AI integration within the next two decades.
- All-In Podcast48 min
Exiled Iranian Prince Reza Pahlavi: Transition Plan and the Fight for Iran's Freedom
Reza Pahlavi, Jason, Prince Reza Pahlavi, Shervin Pishevar
Prince Reza Pahlavi outlines the "Iran Prosperity Project," a 24-month transition framework that rejects personal political ambition in favor of a secular democracy managed by a neutral arbiter to draft a new constitution and hold democratic elections. This strategy leverages reports of the Supreme Leader's elimination and mass military defections to dismantle the regime through unconditional surrender, while promising economic rehabilitation that could generate $1 trillion in US revenue within a decade. The initiative aims to transform Iran into a global innovation hub by restoring historical ties with the West, ensuring territorial integrity, and establishing a clear separation between religion and state.
- Milken Institute59 min
AI and the Future of Digital Transformation | Future of Finance 2026
Nicole Valentine, Jo Jagadish, Karen Kornbluh, Eric Mandl, Igor Tulchinsky, Kip Wainscott
This panel convened finance executives, policymakers, and technology leaders to assess the economic, security, and workforce implications of the next industrial revolution in artificial intelligence. Experts projected multi-trillion dollar market growth and highlighted tangible enterprise gains, such as JPMorgan Chase's $1 billion in fraud savings and TD Bank's rapid AI tool adoption, while warning of existential threats to professional services and national security if human oversight is removed. The discussion concluded that while historical tech shifts ultimately expand workforces, robust legislative guardrails and new standard-setting bodies are urgently needed to balance rapid innovation with public trust and global competitiveness.
- a16z54 min
Atlassian CEO on the SaaS Apocalypse, AI Agents & What Comes Next
Alex Rampell, Erik Torenberg, Mike Cannon-Brookes
The presentation distinguishes between SaaS models based on whether their value is tied to outcomes, processes, or a hybrid of both, noting that AI agents threaten seat-based revenue streams by performing work autonomously rather than merely storing data. It argues against replacing core business systems with "vibe coding," instead advocating for AI that serves as extensible front-ends to established "systems of record" while preserving decades of embedded logic and governance. Finally, the discussion highlights Atlassian's strategy of embedding AI directly into existing workflows like Jira to ensure human oversight and iterative refinement, prioritizing predictable value delivery over uncontrolled consumption-based pricing.
- All-In Podcast1h 23m
War with Iran + Pentagon vs Anthropic with Under Secretary of War Emil Michael
Emil Michael, Jason, Friedberg, Chamath Palihapitiya, David Sacks
The United States and Israel launched "Operation Epic Fury" against Iran, resulting in the death of Supreme Leader Ali Khamenei and the elimination of key regime officials, an operation explicitly framed by the Trump administration as a strategic strike to dismantle nuclear capabilities rather than a regime change effort. This military campaign leveraged a vast arsenal of AI-driven autonomous drones and relaxed rules of engagement to neutralize Iranian defenses while simultaneously severing China's access to vital oil supplies to create maximal leverage for an anticipated trade deal. Concurrently, the Pentagon restructured its defense industrial base by canceling contracts with firms like Anthropic over ideological constraints, prioritizing unfiltered AI providers such as Grok, and deploying a $200 billion lending facility to domesticate critical supply chains for future conflict.