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  1. Sourcery with Molly O'Shea57 min

    Benchmark's AI Bets: Cerebras, Sierra, Legora, Fireworks, Starcloud, Gumloop..

    Ev Randle, Everett Randle, Molly O'Shea, Brad Gerstner

    The event analyzes how the AI paradigm has invalidated traditional software investing rules by decoupling scale from risk and replacing spreadsheet metrics with capital-intensive inference models. It details specific market shifts, including developer spending surges to $36,000 annually per seat, massive liquidity events like Anthropic's $38 billion round, and the emergence of a new valuation framework based on price, quantity, and margin. Finally, the discussion evaluates the long-term implications of these structural changes for venture capital strategies, wealth concentration, and the potential economic disruptions facing the San Francisco housing market.

  2. Sourcery with Molly O'Shea58 min

    Brian Armstrong: Rebuilding Coinbase Around Intelligence

    Brian Armstrong, Molly O’Shea

    Coinbase is launching tokenized equities to democratize access to U.S. stocks for four billion unbrokered users while deploying a network of 1,200 AI agents to drive engineering productivity and financial advisory services. CEO Brian Armstrong outlines a strategic pivot toward an "Everything Exchange" that merges global liquidity with pre-IPO markets, aiming to protect wealth against inflation by enabling a 24/7 agentic economy. This initiative unifies regulatory compliance with advanced infrastructure to replace traditional accredited investor barriers with accessible financial literacy pathways and a proprietary, human-in-the-loop AI architecture.

  3. Milken Institute1h 0m

    Author Talk: Arthur C. Brooks, "The Meaning of Your Life" | Global Conference 2026

    Arthur C. Brooks, Conrad Kiechel

    Arthur Brooks, the author of a recent bestseller and former Harvard professor, addresses a psychogenic epidemic of mental distress by attributing rising loneliness and anxiety to a societal over-reliance on technology and "left-brain" complexity at the expense of human connection and "right-brain" meaning. Drawing on neurobiological research and logotherapy, Brooks advocates for a three-step digital detox and a shift toward vertical and lateral transcendence to reclaim fulfillment, arguing that lasting satisfaction stems from managing desire and cultivating relationships rather than chasing the elusive goal of happiness. His analysis further distinguishes between the damaging pursuit of "specialness" and the liberating reality that love is an unearned gift, offering a framework for individuals to navigate the AI-driven economy by prioritizing complex human problems over complicated technical solutions.

  4. 20VC with Harry Stebbings1h 28m

    DeepSeek Raises at $50B | The Rise of Open Source vs OpenAI & Anthropic | OpenAI Builds Own Chip

    Jason Lemkin, Rory O'Driscoll, Harry Stebbings

    Generational DeepMind researchers Noam Shazeer and John Jumper recently defected to Anthropic to escape bureaucratic constraints, highlighting a market shift where top talent prioritizes autonomy over massive financial packages. Simultaneously, China's DeepSeek secured $7.4 billion with exclusive state voting rights to drive AI sovereignty, while its open-source models are closing the performance gap with US closed-source competitors and threatening the profitability of the industry's middle tier. Amidst this geopolitical and technological realignment, hyperscalers face a $725 billion infrastructure spend against a $100 billion revenue gap, forcing a pivot toward strict ROI verification and labor displacement to justify future trillion-dollar investments.

  5. Milken Institute57 min

    Rewriting the Rules: Scaling Innovation for Rare Diseases | Global Conference 2026

    Becky Quick, Nicola Blackwood, David Fajgenbaum, Michael Hund, Neil Kumar, William H. Lewis

    Panelists including David, Will Osborn, and Michael discussed how AI-driven repurposing of generic drugs and patient-led "venture cure" models are accelerating the discovery of treatments for the over 300 million people globally affected by rare diseases. The dialogue highlighted transformative regulatory shifts, such as the UK's newborn sequencing trials and FDA-authorized umbrella CRISPR studies, which aim to bypass traditional trial inefficiencies while addressing barriers like pricing models that stifle global drug launches. Ultimately, the event concluded that converging data infrastructure with proactive patient advocacy is essential to de-risk development and deliver rapid therapeutic interventions for currently untreatable conditions.

  6. Stanford Online49 min

    Stanford MS&E435 Economics of the AI Supercycle | Spring 2026 | Applications, Coding AI

    Guillermo Rauch, Apoorv Agrawal

    Vercel, a $9.3 billion infrastructure firm founded by Guillermo Rauch, is pivoting its business model from standard web pages to "agentic infrastructure" to support the exponential growth of AI coding agents and token-based consumption. The company leverages a full-stack approach anchored in open source frameworks like Next.js, enabling enterprises such as Meta and Notion to deploy self-driving cloud capabilities that automate software configuration and security. This strategic shift, which has driven a threefold growth rate since October 2024, positions Vercel as the dominant platform for high-velocity, agent-generated code while redefining industry pricing and deployment standards.

  7. All-In Podcast1h 3m

    GameStop CEO Ryan Cohen’s $56B Plan to Take Over eBay

    Ryan Cohen, David Friedberg

    After restructuring GameStop by cutting costs and capitalizing on the collectibles market to generate $9.7 billion in cash, Ryan Cohen proposed a $56 billion acquisition of eBay to merge its physical store network with digital scale. The eBay board rejected this offer citing execution risks and financing uncertainties, prompting Cohen to threaten a hostile campaign involving tender offers to force shareholder value. This confrontation highlights Cohen's strategy of leveraging physical retail for live commerce and digital assets while contrasting his personal financial risk against entrenched eBay management.

  8. Sourcery with Molly O'Shea1h 27m

    Mark Pincus: How to Spot a Fake CEO

    Mark Pincus, Molly O'Shea

    Mark Pincus launches his book *Life at the Speed of Play* to distill four years of entrepreneurial experience into a framework that distinguishes enduring instincts from temporary ideas. The work integrates case studies from Zynga and Tribe.net to advocate for "Proven Better New" product strategies while challenging leaders to prioritize product execution over consensus. Pincus concludes with bullish predictions on AI market consolidation and a call for founders to maintain "Founder Mode" by constantly adapting tactics despite a stable vision.

  9. 20VC with Harry Stebbings1h 17m

    Nikesh Arora on the Frontier Model Problem: Breadth vs Depth | The Future of Token Costs

    Nikesh Arora, Harry Stebbings

    Palo Alto Networks CEO Nikesh Arora outlines a strategic vision where enterprise AI evolves from mere augmentation to agentic judgment, fundamentally reimagining workflows and driving a predicted 50% reduction in administrative headcount. Addressing the cybersecurity landscape, Arora explains how frontier models like "Mythos" accelerate vulnerability discovery while necessitating a shift toward unified, AI-infused gateways to manage autonomous agent traffic. Complementing this technical roadmap, his investment philosophy advocates for early engagement in unproven technologies and warns against current market euphoria, predicting a tenfold drop in token costs that will force a realignment of model valuations based on actual developer utility.

  10. 20VC with Harry Stebbings1h 21m

    Flexport CEO: Two Questions Every Founder Needs to Ask

    Ryan Peterson, Harry Stebbings, Peter Thiel, Masayoshi Son

    Flexport founder Ryan Peterson advocates for a return to five-day in-office work and outlines an aggressive AI-driven strategy to automate logistics workflows, projecting $600 million in net revenue by next year. The company plans to pursue an IPO based on consistent profitability rather than market trends, leveraging open-source models and building proprietary tools to replace traditional SaaS vendors. Peterson also details an investment thesis centered on motivating founders through "revenge and patriotism" while warning of potential labor arbitrage pitfalls and the strategic risks of relying on a concentrated tech ecosystem.

  11. Sourcery with Molly O'Shea1h 22m

    SpaceX Hit $2 Trillion. Now Everyone Wants a Jet

    Israel 'Izzy' Slodowitz, Captain Raz Matus, Israel Slodowitz, Molly O'Shea

    Amidst a surge in ultra-high-net-worth individuals driven by major tech and space IPOs, the private aviation sector is grappling with a severe supply-demand imbalance caused by rapid wealth accumulation and insufficient pilot training pipelines. This unprecedented demand has inverted traditional asset depreciation, causing aircraft prices to rise sharply while operational challenges like corrosion repair and supply chain delays push annual ownership costs to between $2 million and $4 million. Industry experts advise new buyers to prioritize chartering experience over immediate purchase, utilize specific tax incentives like full expensing cautiously, and select aircraft models with robust parts availability to mitigate long-term maintenance risks.

  12. All-In Podcast1h 24m

    World's First Trillionaire, Anthropic Fable Banned, The New Oligarchs, Iran Peace Deal

    Dario Amodei, Chamath, Jason, Friedberg, David Sacks

    Freeburg and Sacks examine the emergence of a new political oligarchy that erodes individual liberties while detailing Elon Musk's record-breaking SpaceX IPO and his strategic acquisition of the coding agent Cursor. The conversation also addresses the U.S. government's forced shutdown of Anthropic's "Fable" model due to national security concerns and outlines a potential ceasefire deal that would resolve the Iran conflict by removing enriched uranium in exchange for sanctions relief. Finally, the speakers project a future of fragmented AI infrastructure and democratized private equity investment, arguing that industry self-regulation is essential to prevent government gatekeepers from cementing a technological oligopoly.

  13. Milken Institute1h 1m

    India Ahead: Growth, Investment, and Global Ambition | Global Conference 2026

    Karan Bilimoria, Haigreve Khaitan, Vivek Lall, Ajay Piramal, Suneeta Reddy

    India's economy, now the world's fourth or sixth largest with a $4 trillion GDP, targets third-place status by 2031 through aggressive manufacturing incentives, digital infrastructure expansion, and a robust legal framework that recently restored its Triple-B+ credit rating. Driven by a youthful demographic, rapid financial inclusion via the Aadhaar system, and strategic shifts in defense and space sectors, the nation has lifted 300 to 400 million people out of poverty while attracting significant foreign investment despite challenges regarding energy security and workforce upskilling. With stable democratic institutions and ambitious reforms in taxation and bankruptcy codes, India is positioning itself as a global innovation hub capable of sustaining long-term growth even as it navigates currency fluctuations and climate resilience needs.

  14. 20VC with Harry Stebbings1h 28m

    Anthropic's Fable Banned by US Government | Wix & Adobe Hit All-Time Lows | Mistral Raising at $20BN

    Everett Randle, Rory O'Driscoll, Harry Stebbings

    The transcript analyzes a record-breaking $2.7 trillion SpaceX IPO that generated a $1.2 trillion surge in Elon Musk's net worth while establishing a "gamma squeeze" market dynamic alongside the U.S. government's first AI model ban on Anthropic's "Claude Fable." These financial and regulatory shifts coincide with Salesforce's $3.6 billion acquisition of Finn, which validates outcomes-based pricing models for legacy SaaS firms, contrasting sharply with the market struggles of Adobe and Wix due to AI-native competition. Investors note a strategic pivot away from pre-AI SaaS toward semiconductor stocks and specialized robotics, marking a critical transition in capital allocation as the industry grapples with sovereign AI constraints and hardware scaling challenges.

  15. Stanford Online50 min

    Stanford MS&E435 Economics of the AI Supercycle | Spring 2026 | Building AI Factories

    Chase Lochmiller, Apoorv Agrawal

    Hyperscalers are pouring capital into AI infrastructure that rivals historic U.S. projects, driven by a shift in bottlenecks from chip availability to securing powered shells and skilled labor. In Abilene, Texas, Crusoe is deploying a 2.1-gigawatt campus hosting tenants like Oracle and OpenAI, where rapid construction faces significant wage inflation due to a scarcity of tradespeople and tripling costs for power equipment. While traditional hardware risks obsolescence, the economic model shows accelerated returns as managed services can halve the payback period to two years, even as the sector grapples with future challenges in labor supply and open-source competition.