Latest Interviews
Showing 106–120 of 822 transcripts.
Clear all filters- Milken Institute59 min
AI and the Future of Digital Transformation | Future of Finance 2026
Nicole Valentine, Jo Jagadish, Karen Kornbluh, Eric Mandl, Igor Tulchinsky, Kip Wainscott
This panel convened finance executives, policymakers, and technology leaders to assess the economic, security, and workforce implications of the next industrial revolution in artificial intelligence. Experts projected multi-trillion dollar market growth and highlighted tangible enterprise gains, such as JPMorgan Chase's $1 billion in fraud savings and TD Bank's rapid AI tool adoption, while warning of existential threats to professional services and national security if human oversight is removed. The discussion concluded that while historical tech shifts ultimately expand workforces, robust legislative guardrails and new standard-setting bodies are urgently needed to balance rapid innovation with public trust and global competitiveness.
- a16z54 min
Atlassian CEO on the SaaS Apocalypse, AI Agents & What Comes Next
Alex Rampell, Erik Torenberg, Mike Cannon-Brookes
The presentation distinguishes between SaaS models based on whether their value is tied to outcomes, processes, or a hybrid of both, noting that AI agents threaten seat-based revenue streams by performing work autonomously rather than merely storing data. It argues against replacing core business systems with "vibe coding," instead advocating for AI that serves as extensible front-ends to established "systems of record" while preserving decades of embedded logic and governance. Finally, the discussion highlights Atlassian's strategy of embedding AI directly into existing workflows like Jira to ensure human oversight and iterative refinement, prioritizing predictable value delivery over uncontrolled consumption-based pricing.
- All-In Podcast1h 23m
War with Iran + Pentagon vs Anthropic with Under Secretary of War Emil Michael
Emil Michael, Jason, Friedberg, Chamath Palihapitiya, David Sacks
The United States and Israel launched "Operation Epic Fury" against Iran, resulting in the death of Supreme Leader Ali Khamenei and the elimination of key regime officials, an operation explicitly framed by the Trump administration as a strategic strike to dismantle nuclear capabilities rather than a regime change effort. This military campaign leveraged a vast arsenal of AI-driven autonomous drones and relaxed rules of engagement to neutralize Iranian defenses while simultaneously severing China's access to vital oil supplies to create maximal leverage for an anticipated trade deal. Concurrently, the Pentagon restructured its defense industrial base by canceling contracts with firms like Anthropic over ideological constraints, prioritizing unfiltered AI providers such as Grok, and deploying a $200 billion lending facility to domesticate critical supply chains for future conflict.
Inside Opendoor: The $2.8B Bet with CEO Kaz Nejatian
Kaz Nejatian, Molly O'Shea, Tobi Lütke, Keith Rabois, Max Weber
CEO Kaz has fundamentally restructured OpenDoor by slashing external spending, enforcing a return to in-office work, and automating property assessments with AI to shift the company from a legacy real estate model to a high-efficiency technical entity. Operating with a $1 annual salary and an intensely hands-on board, Kaz is prioritizing long-term execution over short-term stock performance while replacing standard management with Y Combinator founders to instill a rigorous "founder mentality." This aggressive turnaround aims to stabilize the balance sheet and revolutionize the broken housing market, accepting significant short-term attrition to build a sustainable, high-alpha business.
- Milken Institute1h 0m
Reimagining Mental Health: Innovation at the Intersection of Care & Techn | Future of Health 2025
Rhitu Chatterjee, Amir Inamdar, Patrick Joseph Kennedy, Vik Kheterpal, Upali Nanda, Viviane Poupon
A global summit convened by leaders including Amir Nandar, Patrick Kennedy, and Viviane Poupon addresses a $6 trillion economic burden caused by mental health conditions through integrated strategies spanning pharmaceutical innovation, digital equity, and architectural intervention. Participants highlighted breakthrough therapies like Cybin's CYP003, successful biophilic design projects that reduced medication usage by 30%, and digital monitoring initiatives that engaged 81% of bipolar patients to bridge the gap between chronic care and primary prevention. The gathering concluded with a unified call to reframe mental health as "brain health," urging policymakers to establish liability frameworks for AI and social media while leveraging public-private partnerships to scale accessible, preventative care models globally.
- Milken Institute47 min
The Infrastructure Imperative: Mobilizing Capital for a Resilient Economy | GIS São Paulo
Anya Prusa, Tufi Daher, Karen Fang, Laurent Fayollas, Michael Kelly, Tanya, Eliane
Industry leaders and institutional investors gathered to address the $2.1 trillion global clean energy finance landscape, emphasizing the critical need for stable public policies and de-risking instruments to unlock capital for projects ranging from Brazil's TransNordestina railway to Canada's $15 billion Growth Fund. The panel highlighted emerging technologies like advanced geothermal and carbon capture alongside the transformative potential of AI in grid optimization, while noting that demand-side behavior change and Indigenous legal reforms are essential drivers for scaling decarbonization efforts. Ultimately, the discussion concluded that achieving a balance between affordability, security, and sustainability requires overcoming geopolitical supply chain risks and shifting political focus toward concrete project execution in resource-rich but underfunded regions like Africa.
99.9% of the internet is about to be AI?
World and Merge Labs have secured a direct $250 million partnership from OpenAI to simultaneously combat AI dominance by building a 37-million-user "Proof of Human" network and developing a high-bandwidth brain-computer interface through a new research division. Led by Alex Blania and featuring founding members from Caltech and Forrest Neurotech, the initiative aims to integrate biometric verification into major platforms within months while advancing minimally invasive neural technology with a 15-year consumer roadmap. These dual ventures utilize zero-knowledge cryptography and ultrasound-based sensors to create an anonymous, privacy-preserving ecosystem that generates revenue through network integration fees rather than data sales.
- Milken Institute54 min
End of an Era A Conversation With NBA Great Kobe Bryant | Global Conference 2016
In a candid reflection on his 20-year career, Kobe Bryant explains that his retirement was driven by an internal desire to pivot to storytelling and media rather than physical decline, a decision made independent of team performance or his 60-point finale. Throughout the interview, he details an evolved leadership philosophy centered on "brutal honesty" and the "hero-villain" dynamic, while affirming his enduring mentorship bond with Michael Jordan and reconciled relationship with Shaquille O'Neal. Bryant concludes by urging athletes to cultivate passions outside of sports during their prime, highlighting his current focus on creating fantasy-infused narratives through his "Kobe, Inc." ventures to transform how sports stories are told.
- a16z1h 5m
Inside The Life of Silicon Valley's First Athlete Investor | Magic Johnson
Magic Johnson, Chris Lyons, Earvin "Magic" Johnson, Michael Ovitz, Dr. Jerry Buss
Magic Johnson outlines the strategic transformation of sports franchises into billion-dollar assets, highlighting how ownership shifts toward equity over endorsements and leveraging high consumer demand alongside mobile streaming trends. He details a diversified investment philosophy that prioritizes cash-flow-positive sectors like healthcare infrastructure and AI, while emphasizing the critical need for athletes to build capital reserves and secure mentorship to navigate complex deal executions. Ultimately, Johnson advocates for a collaborative approach where established figures share knowledge and networks to democratize business access, enabling the next generation of athlete-entrepreneurs to capitalize on emerging markets such as women's sports and the NIL economy.
- a16z48 min
AI Markets: Deep Dive with a16z's David George
A leading investment firm projects the AI product cycle as a decade-long growth engine that is accelerating revenue across all quartiles while driving hyperscalers toward $5 trillion in cumulative CapEx by 2030. This thesis is supported by operational shifts where AI-native companies achieve superior revenue per employee and faster adoption rates, alongside portfolio successes in sectors ranging from legal tech to healthcare that validate high-utility models. Despite concerns regarding supply constraints and changing valuation metrics, the analysis concludes that current market dynamics are underpinned by genuine earnings growth rather than speculative froth, with profitability and successful change management identified as the primary drivers of future market leadership.
- Milken Institute1h 3m
Looking Back: A Conversation With Five-Time Super Bowl Champion Tom Brady | Global Conference 2018
Tom Brady confirmed his intention to play through the 2018-2019 season and into his mid-40s by attributing his longevity to the TB12 method's focus on pliability and his refusal to accept injury as inevitable. Addressing the Super Bowl LII loss and his relationship with Coach Bill Belichick, he defended the coaching staff's decisions while acknowledging his wife Gisele Bündchen's role in negotiating his retirement timeline based on family well-being. Beyond the field, Brady emphasized a leadership philosophy that prioritizes internal validation and organizational humility, aiming to inspire a broader cultural shift toward proactive health management.
Inside the $4.5B Startup Building Brain-Inspired Chips for AI
Peter Barrett, Naveen Rao, Konstantine Buhler, Molly O'Shea
Founded by deep tech veteran Naveen Rao and backed by Playground principal Konstantin Buehler, Unconventional AI is raising funds to build a full-stack analog computing platform that leverages silicon's non-linear physics to overcome the energy inefficiencies of current digital systems. The company seeks to automate over 99% of cognitive labor by replacing energy-intensive megawatt-scale data centers with 20-watt biologically inspired architectures, aiming to reach product escape velocity with a projected capital requirement of $1.5 billion. This venture differentiates itself by embracing the stochastic nature of intelligence rather than suppressing it, challenging traditional von Neumann limitations through recurrent dynamical systems that promise computational productivity gains of up to 1,000 times.
- All-In Podcast1h 19m
Epstein Files, Is SaaS Dead?, Moltbook Panic, SpaceX xAI Merger, Trump's Fed Pick
Trump, Brad Gerstner, Kevin Warsh, Jerome Powell, Chamath, Jason, Friedberg, David Sacks
On January 30, the Department of Justice released the Epstein Files Transparency Act documents, prompting J Cal to clarify his limited interactions with Jeffrey Epstein while critics highlight alleged media bias regarding prominent tech figures like Reid Hoffman and Elon Musk. Simultaneously, the market experienced a "Claude Crash" wiping $300 billion from software stocks due to AI disruption fears, though President Trump's nomination of inflation hawk Kevin Warsh to lead the Federal Reserve is expected to support rate cuts driven by AI productivity. In the private sector, Elon Musk announced a $1.25 trillion merger of SpaceX and xAI to build space-based data centers, while the "Invest America" Act successfully launched government-backed investment accounts for newborns to democratize capital ownership.
- Y Combinator46 min
We're All Addicted To Claude Code
Industry analysis indicates a decisive shift toward Command Line Interfaces as the primary interaction layer for coding agents, with Anthropic's Cloud Code utilizing subagent models and OpenAI's Codex employing periodic compaction to manage context windows. Senior engineers are increasingly adopting a managerial role to direct autonomous workflows, while top-tier practitioners distinguish themselves by enforcing rigorous testing protocols and minimizing codebase noise to prevent model degradation. This evolution fosters a tension between rapid, bottom-up grassroots adoption driven by speed and enterprise-mandated top-down security controls, fundamentally reshaping software development structures toward smaller teams operating under vast agent armories.
How Anthropic’s $100M Anthology Fund Works | Menlo Ventures
Menlo Ventures emphasizes investing in founders with authentic long-term conviction and "cult leader" charisma rather than those chasing pre-existing venture capital theses. The firm targets specific opportunities in AI infrastructure, mechanistic interpretability for Goodfire, and industries facing labor shortages where AI solves immediate economic gaps. While noting that massive seed checks risk creating an illusion of success, the discussion highlights a strategic shift toward domain-specific data, economically viable applications, and product-led growth models that prioritize user love over buzzword compliance.