Latest Interviews
Showing 91–105 of 142 transcripts.
Clear all filters- All-In Podcast1h 32m
E55: Valuing crypto projects, Rivian worth $100B+, inflation: causes and corrections and more
Calacanis, Friedberg, Xi Jinping, Chamath Palihapitiya, David Sacks
Hosts David Sacks, Chamath Palihapitiya, and David Friedberg debunked a "pump and dump" conspiracy surrounding Solana while analyzing a macroeconomic bubble characterized by record asset highs, 30-year inflation rates, and massive fiscal stimulus. The panel critiqued public market dysfunction by contrasting Rivian's inflated valuation against fundamental metrics and argued that structural inflation, driven by labor shortages and geopolitical risks in Taiwan, is exacerbated by the U.S. government's reliance on short-term debt. Additionally, the discussion highlighted a corporate deconglomeration trend to unlock shareholder value and described how a crypto-native "shadow economy" is forcing accelerators to evolve their fundraising models amid intense competition between Solana and Ethereum.
- All-In Podcast1h 36m
E35: Biogen's controversial Alzheimer's drug approval, the billionaire space race, Bitcoin & more
Calacanis, Friedberg, Bezos, Buffett, Chamath Palihapitiya
On the Monday of the FDA approval of Biogen's Aducanumab, three advisory panel members resigned unanimously against the decision as the panel discussed the drug's modest efficacy, its $55,000 annual price point, and the structural incentives for physician prescribing. Concurrently, the discourse expanded to include Jeff Bezos's July 2021 suborbital flight plan, the strategic implications of private space dominance against geopolitical rivals, and the divergent remote work mandates adopted by major tech corporations. Finally, the dialogue examined the socioeconomic fallout from leaked IRS data revealing billionaires paying zero federal income tax, the cultural toxicity observed at the Bitcoin Miami conference, and the proposed need for policy reforms to address housing, healthcare, and education.
- All-In Podcast1h 26m
E19: Robinhood's GameStop decision: Why did it happen and how can it be prevented in the future?
David Sacks, Jason, Friedberg, Chamath Palihapitiya
Hosts analyzed the January 2021 GameStop short squeeze, detailing how Reddit users, Michael Burry, and Ryan Cohen pressured institutional shorts while Robinhood's trading restrictions sparked accusations of market manipulation. The discussion highlighted systemic flaws in clearing mechanisms and payment-for-order-flow models, contrasting the collective power of retail investors with risks of mob behavior and centralized censorship. Additionally, the conversation addressed Chamath Palihapitiya's California recall campaign for Governor Gavin Newsom, framing both financial and political movements as challenges to entrenched elite control.
- Goldman Sachs12 min
Edtech Faces the Test
Driven by pandemic-induced necessity, education technology has matured into critical infrastructure, prompting a rapid 40% to 100% demand surge that is fueling aggressive capital deployment and intensifying market consolidation among established and innovative players. While higher education and K-12 sectors face distinct fiscal pressures ranging from enrollment deferrals to state tax declines, accelerated procurement cycles have dismantled traditional bureaucratic friction to facilitate immediate adoption of AI-driven adaptive learning platforms. These structural shifts, characterized by faster decision-making and holistic solution integration, are redefining the sector's operational rhythm and creating a resilient, scale-oriented market despite ongoing economic headwinds.
- Milken Institute1h 15m
Supporting and Strengthening Minority-Owned Businesses During (and After) the Pandemic
Eugene Cornelius, Jr., Susan Au Allen, Ron Busby, Ramiro Cavazos
Susan R. Allen, Ron Busby, and Ramon Calveras led a critical panel discussing the disproportionate pandemic impact on Black, Hispanic, and Asian-owned businesses, where severe capital gaps and procurement barriers forced a 41% loss in Black enterprises and exacerbated economic divisions within the Asian community. The advocates rejected the "minority" label in favor of recognizing these groups as the new mainstream, proposing specific policy interventions such as unbundling federal contracts, reinstating prompt payment laws, and partnering with fintech firms to bridge the historic wealth gap. Moving beyond rhetoric, the panel outlined a concrete agenda to submit a policy white paper to the Treasury Department and encourage institutional mergers, aiming to permanently recalibrate the economy and secure equitable market access for millions of minority entrepreneurs.
- Goldman Sachs23 min
The Power of Advocacy: US Mayors
Eric Johnson, Nan Whaley, LaToya Cantrell
Mayors Eric Johnson of Dallas, Andrew Whitaker of Dayton, and LaToya Cantrell of New Orleans collectively addressed the compounding crises of the COVID-19 pandemic and civil unrest while outlining strategies to support small businesses and protect vulnerable populations. These leaders detailed significant public-private financial partnerships, such as Dallas's $10 million recovery fund and New Orleans' $50 million commitment with Goldman Sachs, to mitigate job losses and address systemic inequities. Furthermore, the mayors emphasized an urgent need for federal assistance and collaborative governance to accelerate economic recovery and build more resilient, equitable urban environments.
- Goldman Sachs15 min
Ben Cardin, Steve Daines, Maggie Hassan, US Senators
Ben Cardin, Steve Daines, Maggie Hassan
Senate leaders utilized bipartisan collaboration and direct stakeholder feedback to pass the Paycheck Protection Program unanimously, successfully adapting its terms to extend loan forgiveness to 24 weeks and adjust spending limits based on real-time economic data. Senators Hassan and Daines highlighted the necessity of combining personal advocacy stories with agile administrative adjustments, such as rapid policy "patches," to effectively support small businesses during the evolving COVID-19 crisis. The committee's focus on shared goals ensured the program addressed diverse friction points while maintaining flexibility for potential future funding rounds to meet ongoing recovery needs.
- Milken Institute57 min
Addressing Mental Health Challenges and Access During COVID-19 - Conference Call Series
Melissa Stevens, Jerome Bettis, Dr. Joshua Gordon, Nancy Lublin
Amid a pandemic that has exacerbated pre-existing mental health crises and disproportionately affected women, people of color, and economically vulnerable populations, experts like Dr. Joshua Gordon and Nancy Lublin highlight the "three-headed monster" of virus, quarantine, and economic collapse driving rising anxiety, isolation, and domestic violence rates. To address these surging needs, digital platforms like Crisis Text Line are scaling remote support models while initiatives such as "Embrace Pittsburgh" attempt to bridge the technology gap for underserved students and families. The collective response emphasizes a shift toward accessible, data-driven interventions that combine community mobilization with systemic changes in healthcare delivery to prevent acute reactions from becoming chronic long-term conditions.
- All-In Podcast1h 7m
E3: Modern Cold War, politicizing the pandemic & more with David Sacks & David Friedberg
David Sacks, David Friedberg, Jason Calacanis, Chamath Palihapitiya
Podcast hosts Jason Calacanis and Chamath Palihapitiya lead a roundtable with guests David Sacks and David Friedberg to analyze pandemic data, economic forecasts, and geopolitical shifts. The group agrees that the infection fatality rate is significantly lower than initially reported and warns of a prolonged two-to-three-year economic recovery marked by a divergence between tech and real sectors. They further predict that widespread mask adoption will allow economies to reopen while discussing the potential for decoupling from China and a long-term decline in San Francisco's prominence due to remote work trends.
- Milken Institute1h 0m
New Pathways to Neuroscience Breakthroughs
Rick Berke, Cara Altimus, Jeffrey Borenstein, Niranjan Bose, Johannes Streffer, Mike Belville, David Mongeau, Janet Knupp, Jing Lu, Ian Kramer, Anna McAllister
A panel of experts highlighted the critical gap in preventing and treating brain disorders despite projections that dementia cases will double over the next three decades. To address historical stagnation and corporate retreat, the discussion emphasized a strategic pivot toward diverse biological hypotheses, early biomarker detection, and philanthropic de-risking led by organizations like the Gates Foundation. This approach aims to overcome diagnostic delays and therapeutic failures by integrating real-world data, stem cell modeling, and patient-centric outcomes to accelerate the development of rapid-acting treatments.
- Milken Institute1h 1m
From Aid to Investment: New Models in Development Finance
Glenn Yago, Richard Blum, Michael Kashani, Jonathan Medved, Stephanie von Friedeburg, Aubrey Ruby, Chukwu The Ugu, Elizabeth Hausler, Henry Lee
The Global Conference convened to address the $5 trillion to $7 trillion annual investment gap required to achieve the UN Sustainable Development Goals by shifting from traditional humanitarian aid to sustainable financing models that attract private capital. Key outcomes included the launch of a $10 billion Asset Management Company, the democratization of venture capital through a platform enabling $10,000 minimum investments, and strategic policy shifts in Israel and Africa to establish new development finance institutions and regional digital infrastructure. By integrating advanced technologies like AI-driven healthcare and satellite census data with novel financial instruments such as green and gender bonds, the event established a framework for scaling impact investing while maintaining financial returns.
- Goldman Sachs10 min
10,000 Small Businesses UK Female Founders on Running a Business
Harriet, Anna, Michal Silver, Rachel
Founders Harriet, Anna, Michal Silver, and Rachel Jackson discuss strategies for navigating entrepreneurial challenges, emphasizing the importance of emotional transparency with investors and reframing difficulties as opportunities for growth. The panelists outline specific tactics for maintaining work-life balance, such as strict digital boundaries and context separation, while offering tailored advice on funding, personnel strategy, and sustaining passion. Their dialogue highlights a shared belief that viewing challenges as solvable problems is a distinct trait among solo female founders who leverage investor relationships for both strategic guidance and emotional reassurance.
- Goldman Sachs15 min
Perspectives from our UK Technology Degree Apprentices
Holly, Karina, Martin, Paul, Sephora
Five diverse apprentices spanning three years of the firm's program discuss how their roles evolved from foundational learning to delivering production-ready projects in fields ranging from trading market data to investment banking technology. Through a robust support system that includes mentors and diversity networks, participants navigate a flat organizational culture that values their insights while balancing rigorous technical exposure with mandatory work-life balance strategies. Ultimately, the cohort endorses the scheme as a transformative alternative to traditional university pathways, highlighting the unique advantage of graduating with an established internal network and hands-on experience in the full software development lifecycle.
- a16z21 min
a16z Podcast | The Blockchain, in Congress
Jared Polis, David Schweikert, Mike Lempres, Matthew Colford
The Congressional Blockchain Caucus, supported by industry leaders like Mike Lamprecht and Congressman David Schweikert, serves as a formal educational forum to bridge the gap between technical innovation and policy implementation for lawmakers often unfamiliar with the technology. While state laboratories like Arizona pilot practical applications such as smart contract recognition and digital vehicle titling, the industry advocates for a clear federal regulatory framework to prevent legacy incumbents from stifling disruption in areas ranging from medical records to personal data sovereignty. Speakers project that technological advancement will continue to outpace government regulation over the next decade, necessitating a legal ecosystem that enables secure financial transfers for the unbanked without hampering the rapid pace of development.
- a16z22 min
a16z Podcast | The Storage Renaissance
Peter Levine, Haoyuan Li, Mike Matchett, Sonal, HY
Industry leaders Peter Levine and HY predict a transformative shift toward unified memory-centric architectures driven by the convergence of falling storage costs and autonomous sensor data generation. This evolution necessitates the replacement of traditional disk and tape systems with fast, cheap memory tiers to support real-time machine learning and edge processing for massive datasets. To overcome current infrastructure silos and anticipated supply shortages, enterprises must adopt a unified abstraction layer while transitioning IT roles from reactive management to proactive data governance.