All-In
Showing 46–60 of 380 transcripts.
- 1h 31m
OpenAI's Identity Crisis, Datacenter Wars, Market Up on Iran News, Mamdani's First Tax, Swalwell Out
Mamdani, Swalwell, Travis Kalanick, Jason, Friedberg, David Sacks, Chamath Palihapitiya
Speakers analyze the economic risks of New York City's proposed 3.9% luxury pied-à-terre tax and the intensifying rivalry between OpenAI and Anthropic as the latter surges to a $30B run rate. The discussion further details how populist backlash and regulatory hurdles are threatening data center expansion, forcing AI firms to pursue independent energy solutions like nuclear and solar power to overcome grid constraints. Finally, the hosts critique market overvaluation amidst geopolitical tensions, debating the scalability of AI enterprise revenue while noting urgent calls for major private companies like SpaceX to pursue initial public offerings.
- 1h 29m
Anthropic’s $30B Ramp, Mythos Doomsday, OpenClaw Ankled, Iran War Ceasefire, Israel's Influence
Brad Gerstner, Chamath, Jason, Friedberg, TheZachEffect, Zach
Anthropic halted the public release of its "Mythos" model after it autonomously identified thousands of critical vulnerabilities, prompting the launch of Project Glasswing, a coalition of forty major firms tasked with patching software flaws. This security breach triggered a heated debate among industry leaders regarding the genuine threat of AI-driven cyber warfare, the necessary government coordination to manage such risks, and the strategic pivot of Anthropic toward dominating the enterprise agent market. Amidst discussions of a temporary AI defense advantage and soaring revenue projections, experts also addressed broader geopolitical tensions and the evolving competitive landscape between frontier AI models.
- 1h 2m
Josh Shapiro on Trump, Iran War Chaos, Israel's Failure, the Economy, and 2028 Race
Josh Shapiro, Trump, Jason, Chamath, Friedberg
Pennsylvania Governor Josh Shapiro combines a record of aggressive economic deregulation and tax cuts with a "zero tolerance" stance on fraud, resulting in the state's only growing Northeast economy and the lowest unemployment in thirty-two months. Facing a divided legislature, he has forged bipartisan wins on business reforms while simultaneously criticizing federal policies, including tariffs and Middle East interventions, for harming local workers and exacerbating national security risks. His broader strategy emphasizes workforce development through expanded vocational funding and the removal of degree requirements for state jobs to address housing costs and economic disparity.
- 1h 9m
The State of Modern War: Palantir & Anduril Execs on Drones, AI, and the End of Traditional Warfare
Shyam Sankar, Trae Stephens, Chamath, Jason, Friedberg, Sean Sankar
Sean Sankar of Palantir and Trey Stephens of Anduril discuss the critical erosion of the U.S. defense industrial base and the urgent need to re-industrialize manufacturing capacity to counter China's dominance in drone and shipbuilding. The dialogue outlines how startups like Anduril are challenging traditional defense monopsonies through private R&D models and modular software platforms, while emphasizing that ethical AI and efficient data aggregation are essential for modern national security. Ultimately, the speakers argue that failing to address these structural gaps and domestic social fractures risks a loss of American global power by 2040, necessitating a shift from rigid government procurement to flexible, consumable defense strategies.
- 1h 21m
SpaceX IPO, Iran War Fallout, Quantum Bitcoin Hack, The Space Opportunity
SpaceX targets a historic $75 billion IPO to achieve a $1.75 trillion valuation while anticipating a future merger with Tesla that would create a $3.1 trillion global entity. The discussion frames this financial milestone against broader risks, including geopolitical instability in the Middle East that threatens global fertilizer supplies and quantum computing advances that could soon compromise current encryption standards. Additionally, the event explores accelerating AI adoption in corporate governance and logistics, alongside a crowded 2026 IPO pipeline featuring potential valuations for OpenAI and Anthropic.
- 1h 20m
Anthropic's Generational Run, OpenAI Panics, AI Moats, Meta Loses Major Lawsuits
Chamath, Jason, Friedberg, Sacks
President Trump has appointed David Sacks and Michael Kratios to co-chair the President's Council of Advisors on Science and Technology, directing a 15-member body to accelerate industrial policy in semiconductors, biotech, and AI while countering China's scientific surge. This appointment coincides with significant market shifts where Anthropic's aggressive enterprise growth challenges OpenAI's declining consumer dominance, prompting Sacks to critique regulatory capture strategies and advocate for parental responsibility over product liability in social media harms. Together, these developments signal a strategic pivot toward aligning government advisory structures with private sector "builders" to manage the transition from scientific discovery to industrial deployment.
- 38 min
Bryan Johnson: I Just Took the Most Powerful Dose of DMT in the World... Here's What It Was Like
Bryan Johnson, David Friedberg
Brian Johnson reports that ingesting a high dose of 5-MeO-DMT induced a 48-hour session of total ego dissolution, effectively annihilating the brain's Default Mode Network to produce a profound metabolic reset and restored youthful neural connectivity. He interprets these neurological changes as a critical mechanism for anti-aging and psychological rejuvenation, complementing his broader longevity protocols that include mitochondrial transplantation, FoxO3 gene therapy, and personalized stem cell organoids. By framing psychedelics as essential tools for "psycho-flexibility" against rapid AI-driven change, Johnson aims to normalize these interventions while acknowledging the risks of unregulated use and the philosophical implications for personal identity.
- 1h 38m
Four CEOs on the Future of AI: CoreWeave, Perplexity, Mistral, and IREN
Michael Intrator, Aravind Srinivas, Arthur Mensch, Daniel Roberts
Michael Moritz, Arvind Srinivasan, Arthur Mensch, and Daniel Roberts discussed the structural evolution of the AI industry, where CoreWeave's securitized financing model, Perplexity's neutral agent-based OS, Mistral's open-source enterprise specialization, and Iron Mountain's energy-first infrastructure strategy are redefining market access. The participants emphasized that while hardware supply remains critical, the primary bottlenecks have shifted to power availability, skilled labor, and the need for sovereign data handling in vertical-specific applications. These strategic pivots collectively aim to accelerate the transition from experimental research to large-scale commercial inference and autonomous agent deployment across diverse sectors.
- 1h 17m
How Matt Mahan Thinks He Can Save California
Matt Mahan, Chamath, Jason, Friedberg, David
San Jose Mayor Matt Mahan entered the California gubernatorial race to challenge the state's fiscal dysfunction by contrasting his record of managing local budgets with the revenue-focused strategies of opponents like Eric Swalwell and Tom Steyer. His platform centers on shifting from process-driven spending to outcomes-based governance, proposing zero-based budgeting to address a $35 billion deficit, reforming pension liabilities to curb long-term costs, and implementing supply-side solutions to resolve the housing affordability crisis. Mahan argues that California's high taxes and regulatory environment have failed to improve key metrics in safety and housing, positioning his administration as a pragmatic alternative that utilizes data dashboards and specific operational reforms to restore economic competitiveness.
- 45 min
John Fetterman: 'I'm the Only Democrat in Congress Saying This'
John Fetterman, David Friedberg
Senator John Fetterman positions himself as a fiscally conservative Democrat who rejects the party's progressive label and current leadership while maintaining full support for recent military strikes against Iran and strict voter ID measures. He argues for prioritizing national security over partisan loyalty, citing concerns over non-citizen voting and the need to counter China's technological rise, though he simultaneously criticizes his party's base for adopting policies that alienate working-class voters. Despite acknowledging internal party dysfunction, Fetterman remains open to a future presidential run as he seeks to bridge ideological divides on issues ranging from immigration enforcement to AI development.
- 1h 16m
Two Legendary Founders: Travis Kalanick & Michael Dell Live from Austin, Texas
Travis Kalanick, Michael Dell, Friedberg, Brad Gerstner
At the All-In Summit, Travis Kalanick officially ended the seven-year stealth phase of his new physical AI venture, Adams, by unveiling a platform that treats atoms like bits to revolutionize food production and mining automation. Concurrently, Michael Dell detailed the explosive growth of his AI infrastructure business and championed the bipartisan Invest America Act, a capital account initiative designed to seed $1,000 for every U.S. child to foster broad-based ownership. Both leaders emphasized a strategic pivot toward Texas as a pro-growth hub for industrial scaling while advocating for aggressive AI integration and open-source collaboration to drive future economic abundance.
- 1h 20m
Iran War, Oil Shock, Off Ramps, AI's Revenue Explosion and PR Nightmare
Brad Gerstner, Howard Schultz, Jason Calacanis, David Sacks
The discussion centers on a dual strategy of domestic wealth redistribution through direct child equity accounts and geopolitical risk management during a volatile conflict in the Middle East that spiked oil prices and inflation. Industry leaders debate the scalability of AI revenue, contrasting production-ready utility against experimental testing, while simultaneously analyzing how "doomerism" narratives and restrictive regulations threaten data center development and profitability. Finally, the program examines the economic consequences of state-level wealth taxes on migration patterns, warning of capital flight and budget shortfalls while advocating for deregulation as a superior alternative to asset seizure.
- 1h 0m
They're Opening the Stock Market to Everyone. Here's What That Actually Means
Jason, Paul Atkins, Michael Selig, Chamath Palihapitiya
SEC Chair Paul Atkins and CFTC regulators outlined a comprehensive agenda to reverse the decline of public capital markets by slashing compliance burdens, redefining accredited investor status, and reducing quarterly reporting requirements. The agencies are simultaneously drafting a harmonized framework for digital assets and AI trading agents to foster innovation while establishing strict guardrails against systemic risk and predatory speculation. These reforms aim to preserve U.S. global competitiveness by balancing reduced regulatory friction for companies with enhanced protections for retail investors against emerging market hazards.
- 1h 3m
“This is Bibi’s War” - Harvard’s Graham Allison on the Influences and Endgame of the Iran War
Graham Allison, Chamath, Jason, Friedberg, Scott Besant
Graham Allison analyzes the current geopolitical landscape by characterizing the escalating Iran conflict as a high-risk campaign driven by Prime Minister Netanyahu's ambitions rather than imminent U.S. threats, while warning that premature regime change could trigger a chaotic power vacuum. Parallel to these Middle East dynamics, Allison assesses a low probability of immediate Chinese aggression on Taiwan due to strategic ambiguity and internal PRC vulnerabilities, even as he identifies extreme domestic wealth inequality in the United States as a primary driver of rising populist instability. The discussion further highlights the critical fragility of the non-proliferation regime and suggests that long-term security for the U.S. and its allies depends on maintaining this status quo rather than pursuing aggressive expansionist maneuvers in the Arctic or elsewhere.
- 48 min
Exiled Iranian Prince Reza Pahlavi: Transition Plan and the Fight for Iran's Freedom
Reza Pahlavi, Jason, Prince Reza Pahlavi, Shervin Pishevar
Prince Reza Pahlavi outlines the "Iran Prosperity Project," a 24-month transition framework that rejects personal political ambition in favor of a secular democracy managed by a neutral arbiter to draft a new constitution and hold democratic elections. This strategy leverages reports of the Supreme Leader's elimination and mass military defections to dismantle the regime through unconditional surrender, while promising economic rehabilitation that could generate $1 trillion in US revenue within a decade. The initiative aims to transform Iran into a global innovation hub by restoring historical ties with the West, ensuring territorial integrity, and establishing a clear separation between religion and state.