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Fireside Chat, Panel

A Conversation with Scott Gottlieb, Commissioner, U.S. Food and Drug Administration

  • The FDA will release a platform within a couple of weeks to guide the integration of digital health tools for patient compliance, symptom measurement, and outcome tracking.
  • Digital health tools used with drugs are expected to be incorporated into product labeling for promotion, bypassing separate pre-market medical device review.
  • Regulatory frameworks aim to facilitate tool development by validating underlying software architecture rather than reviewing specific product iterations.
  • Hundreds of new disease-specific guidances are planned as part of a long-term vision to free clinical staff for patient engagement.
  • Reforms to the Office of New Drugs are projected to improve productivity by approximately 20%.
  • Information regarding the reasoning behind drug approval decisions will likely become available within 48 hours of process conclusion.
  • The first phase of a structured, one-digital-template review memo approach will be implemented around the safety portion of the review process.
  • A knowledge management system is being developed to allow real-time querying of FDA precedents and public access to consolidated intellectual capital.
  • Therapeutic opportunities in novel areas like cell and gene therapy may be foreclosed if reimbursement approaches do not adapt to match innovative drug development paradigms.
  • The FDA expects to break records this year for approvals of novel medical devices, novel drugs, and generic drugs.
  • Data will soon be released indicating that time to second- and third-to-market innovation in novel orphan categories has significantly increased.
  • If policies are executed correctly over a short period, smoking rates are expected to decline dramatically faster than previous trends.
  • Detailed regulations regarding tobacco and e-cigarettes will be provided in approximately four weeks.