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a16z Podcast | Scaling Healthcare

  • Preventable chronic disease is projected to surpass infectious disease as the leading global cause of death, with diabetes-specific costs expected to inflate at a rate of approximately 5% year-over-year.
  • A demographic trajectory where 40% of adults develop type two diabetes poses a risk to the U.S. economy's ability to sustain current disease trajectories.
  • The threshold for employers to transition to self-insurance is expected to decline annually, driving a strategic shift from cost reduction alone to achieving better clinical outcomes.
  • Digital therapeutics and personalized interventions are forecast to generate initial cost savings of 5% to 7% in the first year, with savings projected to increase in subsequent years as long-term consumer relationships are established.
  • Omada Health intends to publish research proving the clinical efficacy of early metabolic disease intervention and will file claims through self-insured plans to facilitate discussions with benefits leaders.
  • Self-insured employers are expected to utilize one-year claims data to demonstrate savings, while Omada Health plans to leverage 24 million structured weight readings to continuously personalize programs based on input, behavior, demographics, and clinical status.
  • Accolade plans to measure performance via consumer engagement levels and ecosystem activation, assuming risk on specific population segments selected by clients to drive savings.
  • Clinical trial outcomes for safety net Medicaid programs are expected to remain comparable to business-as-usual benchmarks.