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Conference Presentation, Product Demonstration, Keynote

Open Evidence Captures Doctors’ Collective Wisdom with AI ft. Zachary Ziegler

  • OpenEvidence Platform Metrics & Adoption
    • The platform is a medical search tool designed specifically for physicians.
    • In the past 12 months, monthly active users reached over 25% of all US practicing physicians.
    • The average user engages with the platform on a daily basis.
  • Case Study: In-Flight Emergency Response
    • Internal medicine physician Dr. Susan Wilber utilized the platform during an in-flight medical emergency involving a 63-year-old male with a severe rash.
    • Initial symptoms suggested chickenpox; the platform confirmed an incubation period of 15 days based on CDC Yellow Book data.
    • The patient's context included prostate cancer and treatment with Xtandi, a drug that induces immunosuppression.
    • OpenEvidence identified the patient's immunosuppression level as "moderate," negating the immediate need to divert the aircraft.
    • The platform provided a treatment protocol based on recent literature from journals like the Journal of Immunotherapy of Cancer.
    • Clinical guidance indicated urgency for medication but not immediate administration (i.e., treatment could wait rather than occur within 30 minutes).
  • Operational Outcome
    • The flight continued without diversion; the patient received treatment upon landing with a positive outcome.
  • Strategic Vision & Future Roadmap
    • The company is currently expanding integration directly into physician workflows.
    • New development focuses on advanced modalities for medical reasoning and medical research.
    • Aggregate Clinical Wisdom Initiative:
      • OpenEvidence is developing capabilities to encode, fetch, and aggregate distributed clinical knowledge currently held by physicians ("wet brains").
      • This system aims to synthesize expert consensus to augment AI-driven answers.
      • A pilot instance was demonstrated within the current week, integrating aggregate wisdom from top gastroenterology specialists to improve specific diagnostic answers.
  • Market Context
    • The system is reported to handle approximately 10 distinct patient interactions per second globally.
Open Evidence Captures Doctors’ Collective Wisdom with AI ft. Zachary Ziegler — Summary