Latest Interviews
Showing 376–390 of 1,549 transcripts.
Clear all filters- Goldman Sachs43 min
Searching for Signals: BlackRock’s Raffaele Savi on the Future of Systematic Investing
Raffaele Savi, Global Head of BlackRock Systematic, leads the firm's 40-year legacy quantitative team overseeing over $317 billion in assets while driving the strategic shift from traditional factor investing to AI-powered models that integrate big data and generative technologies. Addressing recent market volatility with a "dynamism over dogmatism" philosophy, Savi highlights how these advanced tools are expanding systematic capabilities into illiquid private markets and enhancing portfolio resilience against unpredictable shocks. This evolution reflects a decade of growth where hybrid teams blend financial and hard science expertise to navigate complex environments, prioritizing long-term risk management and client outcomes over short-term alpha chasing.
- Sequoia Capital39 min
How AI Digital Minds Can Scale Human Connection ft Delphi’s Dara Ladjevardian
Dara Ladjevardian, Sonya Huang, Jess Lee
Delphi is developing an adaptive platform that constructs personalized "digital minds" using temporal knowledge graphs to capture the specific reasoning, heuristics, and voice patterns of individual users. Following a strategic pivot from licensing public figures to empowering authentic self-created twins, the technology enables high-value applications in enterprise knowledge scaling, personalized education, and automated lead qualification while strictly adhering to identity verification and safety guardrails. Founder Dara predicts that by 2026, these digital representations will normalize as a consumer standard, transforming human energy and authentic connection into a premium economic resource as the market shifts from passive information feeds to active conversational media.
- Y Combinator41 min
Dylan Field: Scaling Figma and the Future of Design
Dylan Field, Evan, Charlie Fearborn, Michael
Figma, led by co-founders Dylan Field and Evan Mock, recently doubled its product ecosystem at its Config event by launching four new tools including Figma Make, which enables prompt-to-app generation to accelerate prototyping. Field emphasizes that as AI commoditizes software development, high-quality design will become the primary competitive differentiator, a shift reflected in Figma's strategy to integrate designers directly into AI research and development teams. The company continues to pivot from its origins as a browser-based design tool to a broader platform supporting seamless design-to-code workflows through acquisitions like Payload CMS and integrations with developer environments.
- a16z43 min
GPT-5 and Agents Breakdown – w/ OpenAI Researchers Isa Fulford & Christina Kim
Isa Fulford, Christina Kim, Erik Torenberg, Sarah Wang
OpenAI leadership and key architects Christina and Issa unveil GPT-5 as a significantly more useful frontier model that prioritizes cross-domain utility, massive coding improvements, and reduced hallucinations over isolated benchmark scores. The update integrates advanced reasoning capabilities and autonomous agent functions to lower barriers for non-technical users while shifting evaluation metrics toward real-world usage data and specialized synthetic datasets. By optimizing pricing and balancing helpfulness against sycophancy, the release aims to establish a new baseline for general intelligence that transforms complex, multi-step workflows into accessible daily tools.
- a16z45 min
From the Dot-Com Crash to the AI Era: How Builders Survive Waves of Disruption
Martin Casado, Raghu Raghuram, Jeetu Patel
The presentation analyzes how VMware was disrupted by cloud computing and containers before examining Cisco's strategic reset to regain innovation velocity by operating as a large startup while targeting tenfold performance gains. Leaders outline a specific execution framework that protects early-stage innovation teams through narrow ideal customer profiles and a product-led culture to navigate the shift from IT buyers to direct end-user adoption. Furthermore, the discussion positions Cisco as essential AI infrastructure, arguing that surging autonomous agent demand will require a 100x expansion in network capacity driven by a hybrid strategy of vertical integration and open ecosystem partnerships.
- a16z37 min
Marc Andreessen: The US is in a AI Arms Race & It Decides The World's Future
A strategic proposal argues that the United States must pivot from a service-based economy to industrial dominance by leveraging embodied AI and robotics to compete with China, citing the historical success of the American System as a model for bootstrapping new manufacturing ecosystems. This transformation aims to resolve deep geographic and economic divides by replacing stagnation-driven populism with rapid productivity growth that lowers costs in essential services like healthcare and housing through deregulation and private-sector innovation. Ultimately, the initiative seeks to form a broad coalition of tech leaders and policymakers to build high-tech "alien dreadnought factories" that restore national security and revive the economic middle class in rural areas.
- Milken Institute27 min
A Conversation with Former Prime Minister of the United Kingdom Tony Blair | Global Conference 2025
Former UK Prime Minister Tony Blair assesses the current global order as a destabilizing "shaking out" rather than a total collapse, highlighting geopolitical stress tests in trade, Ukraine, and the Middle East that demand immediate action. He argues that Europe must overcome its defense dependence on the U.S. while progressive parties regain relevance by adopting artificial intelligence to address economic stagnation and managing immigration through strict, lawful frameworks to counter populist appeal. Ultimately, Blair warns against prioritizing ideology over objective policy solutions, citing his record on child poverty and expressing optimism that long-term trends of rising prosperity and stability will guide the world through these complex crises.
- a16z38 min
The Future of AI Video: How Fal.ai is Making AI Video Faster & Easier
Burkay Gur, Batuhan Taskaya, Jennifer Li
This event details the strategic evolution of a company that pivoted from cloud infrastructure to a multi-cloud generative media marketplace in response to the 2021 GPU crunch and stable diffusion surge. The organization addresses volatile video model dynamics by deploying a proprietary orchestration architecture that manages tens of thousands of GPUs, enabling sub-second inference for fine-tuning and complex chained workflows. Looking ahead, the discussion projects 2025 as a critical tipping point where generative video shifts from single-step generation to enterprise-ready applications in advertising, gaming, and interactive product demonstrations.
- a16z28 min
Health Tech Founders: The Future of Care Is Personalized, Proactive—and AI-Powered
Bryan Kim, Jonathan Swerdlin, Daniel Cahn
Jonathan Sorlin of Function Health and Daniel of Slingshot AI are launching AI-driven platforms that address critical gaps in physical and mental healthcare by transforming reactive medical models into proactive, data-centric prevention systems. Their products prioritize human experience over traditional metrics, utilizing autonomous tools to interpret complex biomarkers and foster therapeutic alliances without replacing human providers. This approach aims to scale access for millions by reducing systemic friction and burnout, ultimately lowering costs while empowering users to maintain autonomy and deepen genuine human connections.
- RAISE Summit26 min
Groq's CEO: A conversation with Jonathan Ross
Grok is establishing a strategic foothold in Europe with a newly operational Helsinki data center that leverages proprietary SRAM-based LPUs to solve critical compute shortages through air cooling and reduced energy consumption. By combining this hardware with a fully automated compiler and sovereign AI partnerships in Saudi Arabia and Canada, the company differentiates itself with a high-volume, low-margin revenue model optimized for sequential token generation. This approach positions Grok as a complementary force to NVIDIA, targeting the lucrative inference market where its architecture achieves superior latency and efficiency while navigating a regulatory landscape it defines as akin to utility infrastructure.
Peter Thiel’s $50M Bet on U.S. Uranium Enrichment, General Matter
Peter Thiel, Scott Nolan, Molly O'Shea
Founded in 2023 by Scott Nolan to address U.S. uranium enrichment deficits, General Matter was selected for two historic Department of Energy programs to secure domestic supply of High-Assay Low-Enriched Uranium (HALEU) and reduce reliance on Russian imports. The company leverages recent executive orders that streamline nuclear regulation and mandate military reactor deployment to tackle the imminent energy gap created by AI demand and flat grid capacity growth. With groundbreaking expected within 12 to 18 months, General Matter aims to establish a large-scale enrichment facility by 2028 to fill the capacity void left by the full ban on Russian uranium.
- Sequoia Capital30 min
OpenAI’s IMO Team on Why Models Are Finally Solving Elite-Level Math
Alex Wei, Sheryl Hsu, Noam Brown, Sonya Huang
Alex Wei, Cheryl Hsu, and Noam Brown led a focused sprint that enabled AI models to achieve gold medal performance at the International Math Olympiad, marking the first instance of a system reaching this elite human benchmark. This breakthrough relied on scaling test-time compute to over 100 minutes of reasoning and deploying self-verification protocols that allowed the model to correctly identify unsolvable problems rather than hallucinating solutions. While the team utilized general-purpose techniques to advance broader reasoning capabilities for future scientific research, they explicitly noted that current constraints prevent solving complex combinatorics or Millennium Prize problems within the required timeframe.
- Y Combinator41 min
Scaling and the Road to Human-Level AI | Anthropic Co-founder Jared Kaplan
This event details how precise scaling laws governing pre-training and reinforcement learning enable predictable AI progress, with task horizons doubling every seven months to support long-term autonomous work. It highlights the launch of Claude 4, which introduces persistent memory and refined coding agents to facilitate complex, multi-day tasks while advocating for a strategic focus on "70% right" applications and greenfield domains like law and finance. The discussion concludes with a roadmap for shifting human-AI collaboration from supervisory oversight to full automation, driven by the expectation that incremental self-correction and hybrid training data will exponentially extend AI capabilities.
Winning the AI Race & Reindustrialization | Christian Garrett, 137 Ventures
Christian Garrett, Molly O'Shea
137 Capital is leveraging government policy shifts in the mining sector and broad economic initiatives to unlock competitive advantages, while simultaneously co-hosting an AI expo with "All In" to pivot public discourse toward tangible industrial benefits. The upcoming event features high-profile speakers including President Trump and various cabinet secretaries who will showcase automation use cases and sign executive orders aimed at accelerating middle-class wealth creation. By bridging Silicon Valley innovation with Capitol Hill strategy, the expo seeks to demonstrate how regulatory changes and vertical integration can secure national security and drive bipartisan technological leadership.
- RAISE Summit23 min
Manus AI Founder, Tao Zhang: Turning Intent into Intelligent Action
Butterfly Effect's co-founder Tao launched Manus AI, an autonomous agent platform designed for non-technical users, following a strategic pivot from the consumer chatbot "Monica." After securing critical infrastructure partnerships with major cloud providers to overcome severe token capacity constraints, the company achieved viral traction with 3.5 million waitlist signups by prioritizing goal-oriented automation over iterative prompting. The product team, led by a fluid executive structure, intentionally simplifies complex model selection to deliver a consumer-grade experience that benchmarks performance against real-world utility rather than public leaderboards.