Latest Interviews
Showing 1456–1470 of 5,628 transcripts.
Clear all filters- a16z46 min
Hey Tech, Come to Healthcare
In a 2022 analysis, analysts BJ and Daisy predict that consumer health technology will produce the world's first trillion-dollar company by leveraging a $4 trillion U.S. market where 88% of the population faces metabolic challenges. The event details how artificial intelligence and post-pandemic cultural shifts are enabling a transition from reactive sick care to predictive, home-centric prevention while bypassing traditional incumbent barriers through new "payvider," marketplace, and financial infrastructure models. These strategies aim to unify fragmented health data and engineer behavioral change, ultimately positioning tech founders with hybrid clinical expertise to replace legacy systems with AI-driven, high-UX solutions.
- Goldman Sachs9 min
Why emerging markets could keep rallying
Stratford Dennis, Mike Washington
Goldman Sachs projects a 10% rally in MSCI Emerging Markets equities through year-end, driven by positive growth differentials, a weaker US dollar, and widespread institutional underweight positioning. Analysts favor "EM ex-China" strategies over Chinese assets while specifically highlighting Brazil as a high-conviction opportunity supported by attractive valuations and expected rate cuts. The firm recommends purchasing upside calls on dollar-denominated Brazilian indices to capitalize on this convergence, framing the broader shift toward emerging markets as a multi-year structural trade dependent on US bond market stability.
- Goldman Sachs30 min
Alnylam’s Yvonne Greenstreet on RNAi and a ‘golden era’ in biotech
Alnylam Pharmaceuticals leverages a decade of RNA interference research to achieve a 55% clinical success rate and recently secured approval for Amvutra to treat hereditary transthyretin-mediated amyloidosis. Under CEO Yvonne Greenstreet, the company aims to become a top-five biotech leader by 2026 through a five-year strategy to deliver 25 clinical programs and expand into common diseases like hypertension. To reach this goal, Alnylam integrates AI-driven drug design with a culture of diversity and patient advocacy to de-risk development and target tissues beyond the liver, including the central nervous system.
- Milken Institute57 min
From Experience to Excellence: Women Redefining Business and Financial Wellness | Global Conference
Sheryl WuDunn, Sheila Marcelo, Lauren Miller Rogen, Penny Pennington, Michele Trogni, Michelle Choney
This panel convened financial leaders, health innovators, and care advocates to address systemic failures in institutions designed around male lifespans, highlighting that women over 45 now launch businesses at twice the rate of men despite facing significantly higher chronic illness rates and lower retirement savings. Through initiatives by Zinnia, Edward Jones, Hilarity for Charity, and Ojai.ai, the discussion proposed a holistic framework integrating financial longevity, AI-driven household management, and brain health education to transition from "work-life balance" to comprehensive power. The resulting strategy advocates for redesigned risk profiles, early protective insurance planning, and intergenerational conversations to secure the $10 trillion in assets currently held by women against the projected demographic shifts in caregiving and wealth transfer.
- All-In Podcast25 min
Nico Rosberg on the Booming Business of F1 | All-In Live from Miami
Nico Rosberg, Chamath, Jason, Friedberg
Former 2016 Formula 1 World Champion Nico Rosberg detailed his strategic pivot from racing to venture capital, highlighting significant portfolio investments in AI and software while cautioning against the complexities of the European hardware market. The discussion further analyzed the sport's evolution, noting how rigorous safety innovations and a $130 million budget cap have transformed F1 into a highly profitable enterprise with valuations reaching $6 billion per team. Rosberg emphasized that the sport's recent success stems from a blend of advanced driver training, a Netflix-driven demographic expansion, and the unique convergence of traditional sports with the digital finance ecosystem.
- a16z1h 45m
Beyond Leaderboards: LMArena’s Mission to Make AI Reliable
Anjney Midha, Anastasios N. Angelopoulos, Wei-Lin Chiang, Ion Stoica
LM Arena has transformed from a static benchmark into a dynamic "humanity's exam" that evaluates over 280 AI models through real-time feedback from one million monthly users, effectively eliminating data contamination through fresh prompt generation. By treating evaluation as Reinforcement Learning rather than Supervised Learning, the platform utilizes techniques like "style control" and the open-sourced "Prompt-to-Leaderboard" router to achieve twice the performance-per-cost while maintaining academic neutrality. Looking forward, the organization plans to expand into private industry-specific Arenas and multi-modal agent testing while remaining committed to open-sourcing all data and research to preserve ecosystem trust.
- The Diary Of A CEO1h 31m
The Foot Expert: Your Toes Can Predict If You’ll Die Early! This Will Fix Plantar Fasciitis!
Dr. Courtney Conley and host Stephen Bartlett examine the critical link between foot health, longevity, and mental well-being, highlighting how modern footwear compromises natural mechanics to cause widespread mobility issues. The discussion details how narrow, cushioned shoes exacerbate conditions like plantar fasciitis and depression, while prescribing a transition to zero-drop footwear and specific strength exercises to restore intrinsic muscle function. By addressing root causes such as overstriding and weak musculature, the speakers advocate for a functional approach that reduces cardiovascular and mortality risks while empowering individuals to maintain movement as a fundamental mode of survival.
- Milken Institute21 min
A Conversation with Eric Schmidt | Global Conference 2025
Eric Schmidt analyzes the evolving Ukraine conflict as a volatile stalemate driven by massive drone production, automated sensor-to-shooter loops, and the obsolescence of traditional armored platforms like tanks and aircraft carriers. He contrasts Ukraine's rapid, two-week innovation cycles against the Pentagon's sluggish 16-year procurement process, arguing that rigid bureaucratic structures prevent the U.S. from adopting necessary autonomous systems. Schmidt concludes that to counter modern hypersonic threats and future high-intensity warfare, the U.S. must pivot from expensive stationary assets to affordable, internet-prosecuted robotic forces integrated with its domestic startup ecosystem.
- Jane Street1h 20m
Building Tools for Traders with Ian Henry
Ian Henry, Ron Minsky, Mark Mandelbaum, Mark Mirchandani, David Eastman, Brian Dorsey
Ian Henry, a Jane Street engineer who transitioned from general web development to options trading tools, leverages the firm's custom OCaml ecosystem to build high-density interfaces that eliminate mouse usage and manage complex volatility surfaces. His recent work includes creating Bauble, a live 3D graphics environment in the Janet language that demonstrates how side projects using image-based state serialization and novel macro systems can rapidly inform internal production tooling. Through this process, Henry illustrates how Jane Street bridges the gap between low-latency exchange architecture and expert user needs by prioritizing type safety, extreme information density, and a parallel software universe free from standard web protocols.
- Y Combinator1 min
In the AI era, the playbook is changing.
As the saturated pre-AI startup landscape shifts, the prevailing advice urges founders to abandon the risk-averse "lean startup" methodology in favor of a new "hard set" mental model driven by curiosity and emerging technology. By positioning themselves at the edge of the future, entrepreneurs can organically discover viable opportunities through active exploration rather than forcing premature validation. This approach reframes idea generation as a discovery process where technical feasibility is determined by engaging with cutting-edge innovations rather than strict pre-build market analysis.
How Wander Raised Over $100M+ to Reinvent Luxury Travel
Wander, a verticalized vacation rental marketplace led by founder John Andrew, recently secured a Series B term sheet with QED to scale its curated inventory of top-tier properties beyond 1,000 locations. The company differentiates itself through a proprietary AI-driven operating system that automates 60% of management tasks and maintains strict brand safety standards while transitioning from an asset-heavy balance sheet to a REIT-based model. With a $40 million GMV run rate and a $100 million annual revenue target, Wander is restructuring into business units to support efficient growth toward Series C while prioritizing operational frugality and ethical cultural fit.
- Milken Institute1h 13m
The Milken-Motsepe Prize in FinTech Pitches and Grand Prize Ceremony | Global Conference 2025
Milken, Motsepe, Emily Musil, Meghan McCormick, Precious Moloi-Motsepe, Sam Njuguna, Ola Oyetayo, Jonathan Wilson
The 2025 Milken-Motsepe Prize awarded $2 million to ten semi-finalists to support African-led FinTech innovations targeting underbanked populations, with Virto securing the $1 million grand prize for its cross-border payment infrastructure. Key figures including Mike Milken and Patrice Motsepe emphasized the program's role in leveraging Africa's demographic growth and entrepreneurship to catalyze follow-on investment and impact over one million lives since its inception. Building on this momentum, the initiative launched a new accelerator and announced an upcoming challenge cycle in AI and Manufacturing to further address financial inclusion and infrastructure gaps across the continent.
- a16z1h 18m
Rick Rubin: Vibe Coding is the Punk Rock of Software
Rick Rubin, Marc Andreessen, Ben Horowitz, Anjney Midha, Erik Torenberg
Rick Rubin introduces "vibe coding" as a methodology merging the ancient spiritual principles of the Tao Te Ching with modern AI to democratize creation for non-technical users. The discussion outlines how this approach treats AI as a tool for human expression rather than an autonomous creator, aiming to counteract the homogenization of global culture and narrow demographic biases in current tech development. Ultimately, the event advocates for a future of education focused on cultivating taste and self-knowledge, allowing artists to leverage AI to raise creative ceilings while maintaining authentic individual agency.
- a16z21 min
7 More Healthy Years: What We Can Learn from Super Agers
The proposed healthcare strategy shifts focus from unproven aging reversal to preventing the "big three" age-related diseases through modifiable lifestyle factors and emerging medical technologies. By integrating personalized omics data, AI-driven risk profiling, and novel treatments like GLP-1 drugs and cellular therapies, this approach aims to extend healthspan by seven years for populations globally. This evidence-based framework prioritizes immediate disease mitigation over theoretical longevity, leveraging a 20-year incubation window to fundamentally redefine the standard of care.
- Goldman Sachs24 min
How AI, tariffs, and the energy transition are reshaping infrastructure investing
Large institutional investors have allocated 6% to 7% of assets to infrastructure, a sector that generated nine percent returns since 2022 while evolving from traditional transport dominance to focus on energy transition and digital assets like AI-driven data centers. Goldman Sachs identifies key opportunities across four segments, noting that solar plus storage is now cost-competitive and that European markets are gaining traction due to Germany's massive infrastructure plan, despite geopolitical and liquidity risks in specialized areas. To capitalize on these secular trends in decarbonization and digitalization, investors utilize closed-ended funds targeting mid-teens returns or evergreen vehicles for long-term capital appreciation.