Latest Interviews
Showing 376–390 of 1,333 transcripts.
Clear all filters- All-In Podcast1h 45m
Inauguration Interviews: Trump's Talent, Dem Rebrand & more w/ Whip Emmer, Reps Swalwell & Khanna
Trump, Whip Emmer, Reps Swalwell, Khanna, Tom Emmer, Eric Swalwell, Shamath Palihapitiya, David Friedberg
Republican Representative Tom Emmer and Democrats Eric Swalwell and Rohit Khanna critique the Democratic Party's 2024 nomination process and ideological drift while debating Republican fiscal priorities, immigration strategies, and regulatory approaches to technology. Emmer advocates for rapid deficit reduction and a two-tiered immigration plan, whereas Swalwell and Khanna emphasize preserving social safety nets, implementing points-based labor immigration, and opposing mass deportations. The panel further contrasts views on national security measures like a TikTok ban and potential cabinet confirmations, ultimately highlighting the need for pragmatic governance over ideological purity to address critical issues from wildfires to economic revitalization.
- Lex Fridman3h 54m
Jennifer Burns: Milton Friedman, Ayn Rand, Economics, Capitalism, Freedom | Lex Fridman Podcast #457
Jennifer Burns, Milton Friedman, Ayn Rand, Lex Fridman
This analysis contrasts Milton Friedman's data-driven, pragmatic approach to monetarism with Ayn Rand's axiomatic, mythic defense of Objectivism to explain their divergent impacts on the conservative movement. By examining Friedman's influence on central bank policy and Rand's creation of a cultural "cult," the discussion elucidates how their competing methods shaped modern economic thought and the recent backlash against neoliberal globalization. The overview further extends these themes to contemporary geopolitical strategy, illustrating how the evolution of these ideas informs current debates on peace negotiations and market regulation.
- 80,000 Hours2h 38m
'Future bias' and a possible solution to moral fanaticism | Christian Tarsney (2021)
Christian Tarsney, a philosopher at Oxford's Global Priorities Institute, addresses core epistemic and decision-theoretic challenges in long-termism by introducing a framework where stochastic dominance with background uncertainty justifies prioritizing existential risk reduction while rejecting irrational "fanatical" choices. His research demonstrates that despite the exponential decay of influence over centuries, long-termist interventions remain robust under plausible assumptions, and he resolves the tension between moral externalism and internalism through moderate externalist decision rules that incorporate agent-specific beliefs. The event concludes with practical career insights for the expanding field of global priorities research, emphasizing the hiring of philosophy and economics PhDs to tackle existential threats and institutional improvement.
- 80,000 Hours1h 53m
Misinformation during disease outbreaks | Tara Kirk Sell (2020)
Tara Kirkell of the Johns Hopkins Center for Health Security critiques the U.S. federal government's inconsistent pandemic response and eroded public trust while advocating for evidence-based strategies like mass contact tracing and risk-matrix reopenings. Drawing on data from the Center's Disease Prediction Project and new funding from the Open Philanthropy Project, she highlights the critical need for improved surveillance, early testing capacity, and technological innovations to prevent future biological catastrophes. The analysis contrasts U.S. failures with successful international models and emphasizes that long-term biosecurity requires shifting from reactive panic cycles to sustained investment in generic countermeasures and disease forecasting infrastructure.
- All-In Podcast1h 43m
Red-pilled Billionaires, LA Fire Update, Newsom's Price Caps, TikTok Ban, Jobless MBAs
Mark Pincus, Jason, Friedberg, Chamath Palihapitiya
Venture capitalist Mark Pinkus discusses his political realignment from the Democratic establishment to endorsing Donald Trump following a catalyst of media skepticism and the removal of internal gatekeepers, a shift that paradoxically strengthened his relationship with friend and co-investor Reid Hoffman. The conversation expands to California's record-breaking wildfire crisis, where experts debate the efficacy of Governor Newsom's price gouging bans and real estate moratoriums against historical precedents for rapid infrastructure recovery. Additionally, the speakers analyze the impending TikTok ban driven by national security concerns, the disruptive impact of generative AI on traditional MBA career paths, and Pinkus's ongoing investigation into the Fermi Paradox and potential UAP phenomena.
- 80,000 Hours2h 22m
Building the world’s first great source of COVID-19 data at Our World in Data | Max Roser (2021)
Founded by Max Rosa at Oxford University, the non-profit Our World in Data evolved from a small academic team into a global pandemic resource that outperformed major health institutions through its accessible visualizations of fragmented data. The organization operates with a hybrid staff of researchers and developers funded by unrestricted donations, creating vital databases for vaccination rates and energy statistics that serve as the primary reference for media outlets and policymakers worldwide. Despite facing challenges regarding funding for infrastructure and accusations of bias, the project continues to expand its scope into mental health and conflict studies while advocating for reforms that value public data tools within the traditional academic system.
- Dwarkesh Patel2h 14m
Sarah Paine — The war for India (Lecture & interview)
This analysis examines how strategic miscalculations by the U.S. and China over the past seven decades reshaped the Himalayan geopolitical landscape, from the 1950 annexation of Tibet to the 1962 Sino-Indian War. Key outcomes include the permanent U.S. estrangement from India due to Cold War alliances with Pakistan, the strategic realignment triggered by the 1969 Sino-Soviet border conflict, and the long-term nuclear proliferation driven by limited, non-regime change warfare. The presentation concludes that future stability relies on recognizing immutable regional adversarial coalitions rather than attempting to maintain contradictory alliances or intervene in protracted conflicts that resist resolution.
- The Diary Of A CEO1h 47m
The Keto Psychiatrist: What Keto Is Really Doing To Your Body! Can It Cure 43% Of Mental Illness?
Dr. Ede advocates for metabolic psychiatry, a field asserting that inflammation and insulin resistance are primary drivers of mental illness, presenting data where ketogenic interventions induced remission in 43% of patients with chronic, treatment-resistant conditions. Clinical evidence from inpatient studies and pilot trials demonstrates that sustained ketosis significantly reduces psychiatric medication loads and anxiety within weeks by stabilizing brain metabolism and cortisol levels. This approach necessitates a multidisciplinary strategy combining low-carb nutrition, precise metabolic monitoring, and therapeutic support to address root causes rather than merely managing symptoms.
- The Diary Of A CEO2h 28m
Jordan B Peterson: You Need To Listen To Your Wife! We've Built A Lonely & Sexless Society!
Psychologist Jordan Peterson argues that modern society faces a crisis of meaning and alienation driven by individualism, pornography, and a rejection of traditional religious structures that historically fostered social cohesion. He contends that individuals must confront their own suffering and voluntarily sacrifice comfort to build competence and desirable lives, thereby finding purpose through hierarchical social roles rather than hedonistic consumption. Ultimately, Peterson asserts that sustainable happiness and meaningful relationships require embracing difficult truths, engaging in voluntary self-sacrifice, and replacing the pursuit of pleasure with the active quest for virtue and responsibility.
- 80,000 Hours2h 58m
"Put up or shut up": working in AI and improving the news | Max Tegmark (2022)
Physicist Max Tegmark has pivoted his MIT research to address existential risks by founding the Future of Life Institute, which has secured millions in grants from figures like Elon Musk and Vitalik Buterin to advance AI safety, biosecurity, and nuclear non-proliferation. His work focuses on developing "intelligible intelligence" to prevent catastrophic black box scenarios, alongside the "Improve the News" project designed to mitigate societal fragmentation through machine learning. By applying effective altruism principles, Tegmark coordinates a multi-faceted strategy to align corporate incentives, regulate general-purpose AI, and steer humanity toward flourishing rather than self-destruction.
- All-In Podcast1h 47m
LA's Wildfire Disaster, Zuck Flips on Free Speech, Why Trump Wants Greenland
Zuck, Trump, Cyan Banister, Chamath, Jason, Mark-Zuckerberg
Panelists dissected the catastrophic Palisades Fire as a product of extreme climate conditions and systemic policy failures involving environmental regulations and insurance market collapse. The discussion expanded to critique current California leadership, with calls for business executives to replace career politicians, while simultaneously analyzing Meta's strategic shift away from third-party fact-checking. Further topics included NVIDIA's new edge computing hardware for AI and robotics, the geopolitical imperative of securing Arctic shipping lanes, and predictions regarding future market shifts in the S&P 500 and US national debt.
- 80,000 Hours1h 37m
Whether we're winning or losing against COVID-19 | Marc Lipsitch (2020)
Mark Lipsitch and other epidemiological experts analyze the US pandemic response, critiquing strategic failures like delayed testing and flawed modeling while highlighting the importance of sustainable field infrastructure and faster grant cycles. The discussion outlines evidence-based recommendations for future preparedness, including massive testing scale-ups, ethical human challenge trials, and the need for a peacetime ecosystem of researchers capable of pivoting to new threats. Additionally, the event provides career guidance for quantitative specialists and announces the rescheduling of the Effective Altruism Global conference to a virtual format featuring consensus-based policy guidelines.
- The Diary Of A CEO1h 38m
Get Your Sex Life Back! What Everyone Gets Wrong About Sex, Libido & Erectile Dysfunction - Dr Khera
Dr Khera, Dr Mohit Khera, Steven
Dr. Mohit Khera introduces "sexspan" as the goal of aligning satisfying sexual activity duration with overall lifespan, highlighting that current statistics reveal significant gaps for both men and women due to conditions like erectile dysfunction and female sexual dysfunction. The presentation details how these sexual health issues often serve as early predictors for cardiovascular disease and depression while outlining evidence-based interventions ranging from lifestyle modifications like weight loss and exercise to advanced medical treatments such as daily Cialis and testosterone replacement therapy. Ultimately, Dr. Khera argues that addressing these physiological and psychological barriers through open communication and emerging regenerative therapies is essential for optimizing long-term relationship health and longevity.
- 80,000 Hours2h 38m
Epistemic systems & layers of defence against global catastrophes | Owen Cotton-Barratt (2020)
Owen Cotton-Barratt, Rob Wiblin, Arden Kaler
The Oxford Future of Humanity Institute is launching a fully funded, two-year Research Scholars Program designed to help early-career researchers explore existential risk topics without the pressure of immediate thesis production. This initiative coincides with the development of the "Defense in Depth" framework, which analyzes extinction risks across origin, scaling, and termination stages to justify investment in resilient, later-stage interventions. To support the broader community, the program also promotes a "Web of Virtues" strategy that prioritizes clarity, scope sensitivity, and cooperation as robust methods for navigating uncertainty and guiding future decision-making.
- The Diary Of A CEO2h 4m
Exercise & Nutrition Scientist: The Truth About Exercise On Your Period! Take These 4 Supplements!
Dr. Stacey Sims highlights the critical gap in sports science where protocols based on male data disadvantage women, leading to unique risks in injury, metabolic function, and recovery. Her research details how physiological differences in muscle morphology, hormonal cycles, and nutritional needs require sex-specific training, nutrition, and supplementation strategies. Addressing these biological distinctions is essential for developing effective health guidelines that support female performance across all life stages, from puberty to menopause.