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  1. Milken Institute55 min

    The Promise of Public Health

    Mike Klowden, Richard Besser, Nancy Brown, Thomas Farley, Joseph Jimenez, Fred Upton

    The Milken Institute's inaugural Public Health Summit convened key industry and government leaders, including Novartis CEO Joe Jimenez, CDC Director Tom Frieden, and Congressman Fred Upton, to advocate for elevating disease prevention alongside medical cures. Participants analyzed critical strategies such as conditional reimbursement models, real-time data utilization, and the "21st Century Cures Act" to address looming challenges posed by an aging global population and stagnant biotech venture capital. The consensus emphasized that sustainable health outcomes require shifting from volume-based treatment to outcome-based policies that integrate genomics, behavioral interventions, and bipartisan legislative support to bridge significant disparities in US public health metrics.

  2. Milken Institute21 min

    Atul Butte | Driving Public Health: A Trillion Points of Data

    Atul Butte

    Addressing the exponential growth of biomedical data, the presentation details UCSF's initiative to consolidate electronic records from 14.1 million patients into a unified warehouse that shifts disease tracking from code-based to molecular-based systems. This infrastructure enables low-cost computational predictions, such as the rapid repurposing of imipramine for lung cancer, which accelerated a clinical trial from concept to authorization within fifteen months. By creating dynamic maps of patient disease progression, the project aims to redefine accountable care through continuous, population-level monitoring rather than isolated clinical encounters.

  3. Milken Institute51 min

    Infectious Diseases: Staying One Step Ahead

    Michael Gerson, Michael Kurilla, Vanina Laurent-Ledru, Pranav Shetty, Moncef Slaoui

    Experts including Vanina Laurent Ledru of Sanofi Pasteur and Monsef Slaoui of GSK advocate shifting global health strategy from reactive outbreak response to proactive prevention to counter drivers like climate change and increased mobility. Leveraging platform technologies and industrial-scale manufacturing, the industry aims to bypass the traditional decade-long vaccine development cycle for threats such as Ebola, Zika, and pandemic flu while addressing critical gaps in local infrastructure and surveillance. Despite improvements in specific regions, the panel concludes that long-term consistency in funding and international cooperation is essential to prevent future crises from overwhelming fragile health systems.

  4. Milken Institute46 min

    A Future of Healthy Aging

    Paul Irving, Pinchas Cohen, Linda Fried, Freda Lewis-Hall, Robin Mockenhaupt

    A global panel convened to address the critical misalignment between rising life expectancy and stagnant healthspan, framing older adults as an underutilized human capital asset essential for the 21st-century economy. The discussion highlighted that delaying Alzheimer's onset by five years could halve annual caregiving costs and proposed a "Frieden's Triangle" strategy combining genomic risk assessment, social engagement programs, and targeted public health policies to transform prevention. To realize this vision, the group advocated for a "third demographic dividend" through a tenfold increase in federal funding, clinical trial reforms for geriatric populations, and the creation of new social institutions designed specifically for the emerging thirty-year life stage.

  5. Milken Institute54 min

    The Health of Nations: Meeting the Sustainable Development Goals

    Matthew Bishop, David Barash, Stefano Bertozzi, Deborah Birx, Jacqueline Shea

    A panel of global health experts and industry leaders convened to evaluate the gap between current Social Progress Index trajectories and the ambitious targets set by the UN Sustainable Development Goals. The discussion highlighted critical failures in data granularity, vaccine development funding, and the unique health crises facing high-income nations like the United States. Experts concluded that achieving these goals requires a strategic pivot from charity-based models to shared-value ecosystems driven by granular data, impact investing, and cross-sector innovation.

  6. Milken Institute16 min

    Barbara Bush | Resilience in Global Health Leadership

    Barbara Bush

    Founded in 2009 by Barbara Bush and five peers, Global Health Corps addresses global health leadership gaps by competitively selecting and training diverse millennial fellows through a specialized curriculum developed with Yale and Harvard. The organization has placed 600 young leaders into 70 partner organizations across Africa and the United States, resulting in a 97% sector retention rate and measurable policy impacts among alumni. By focusing on systems change and resilience, Global Health Corps aims to cultivate a new generation of executives who will fundamentally restructure healthcare delivery to ensure universal access within two decades.

  7. Milken Institute1h 2m

    Lunch Program │ An Update on Zika Virus With CDC Director Tom Frieden

    Tom Frieden, Mike Klowden, Michael Gerson, Lynn Goldman

    CDC Director Thomas Frieden and other health experts highlight that public health interventions have driven a disproportionate share of modern economic growth by dramatically extending life expectancy through vaccines, global partnerships, and improved chronic disease management. Addressing current threats like Zika, the speakers emphasize accelerated testing capabilities and the Global Health Security Agenda's accountability framework while contrasting rapid biological changes in life spans with slower genetic evolution. The presentation further illustrates how environmental factors, epigenetics, and escalating portion sizes significantly influence health disparities and disease rates independent of genetics.

  8. Milken Institute50 min

    Superbugs: Slowing the Spread of Antibiotic-Resistant Bacteria

    Maryn McKenna, Beth Bell, Barry Eisenstein, Lance Price, Zachary Rubin

    Unchecked antimicrobial resistance threatens to cause 10 million global deaths and $100 trillion in economic losses by 2050, driven by stalled pharmaceutical innovation, agricultural misuse, and rapid pathogen spread. Critical failures in current stewardship and reimbursement models have allowed superbugs like CRE and MCR-1 to emerge, undermining essential medical procedures from cancer treatment to organ transplantation. Urgent interventions including international data sharing, regulatory incentives for novel antibiotics, and a shift in clinical and agricultural practices are now essential to prevent a post-antibiotic era.

  9. Milken Institute47 min

    Big Data, Small Devices: How Technology Is Advancing Public Health

    Anna Barker, Helen Burstin, Atul Butte, Eric Friedman, Kyu Rhee

    This panel discussion highlighted the explosive growth of global data, noting that internet-connected devices now number 50 billion while genomic sequencing efforts aim to process the health records of 25% of the world's population by 2025. Experts outlined strategic shifts toward predictive, personalized, and preventative care models utilizing IBM Watson and wearable technology to bridge the decade-long gap between research discovery and clinical application. The dialogue concluded by addressing critical challenges regarding data interoperability, digital equity, and the transition from episodic treatment to continuous population-level monitoring through distributed data ecosystems.

  10. Milken Institute56 min

    Mental Health: A Global Challenge We Can't Ignore

    Margaret Anderson, Olga Acosta Price, Pamela Collins, Paolo del Vecchio, Charles Ingoglia

    This panel convened experts to address the global crisis where mental disorders cause over 8 million annual deaths and severely limit life expectancy due to systemic resource scarcity and stigma. Researchers and policymakers highlighted the shift toward neurodevelopmental and immunological models while stressing that 75% of children with needs remain untreated because of misaligned funding and fragmented care delivery. The discussion concluded with urgent calls for legislative action, including the proposed "Excellence in Mental Health Act," to mandate evidence-based standards and transition payment models toward value-driven outcomes.

  11. Milken Institute52 min

    Waistlines of the World: An Update from the War on Obesity

    Cristina Alesci, Patrick Carroll, William Dietz, Debra Eschmeyer, Jonathan Fielding, David Heber, Bill Dietz

    A comprehensive panel analysis reveals that while childhood obesity rates have plateaued, adult prevalence continues to rise driven by socioeconomic disparities and addictive food environments. Experts advocate for multi-layered interventions ranging from sugar taxation and corporate incentive programs to person-first language policies to combat social stigma. Ultimately, the discussion emphasizes that preventing obesity through early childhood education and sustainable dietary shifts is more economically viable than treating the condition later in life.

  12. Milken Institute51 min

    The Avoidable $4 Trillion Toll of Global Hypertension

    Lynn Goldman, Kenneth Connell, Nieca Goldberg, Stephen Kopecky, Paul Whelton, Gil Oman

    Experts convened to address the global epidemic of untreated hypertension, which imposes a $4 trillion annual economic burden and drives rising rates of stroke and heart attacks, particularly among aging and African-American women. Through clinical reviews of the SPRINT trial and lifestyle interventions like the DASH diet, the discussion highlighted that aggressive targets below 120 mmHg and sodium reduction can significantly lower mortality, yet current adherence remains critically low. Case studies such as Barbados' Standardized Hypertension Treatment Project demonstrated that protocol-based, team-driven care combined with home monitoring can transform control rates, offering a scalable model for health systems seeking to close the gap between diagnosis and effective treatment.

  13. Milken Institute50 min

    Inner-City and Rural Health Care: Bridging the Gap in Access to Services

    Dan Diamond, Jehan El-Bayoumi, Jewel Mullen, Raul Pino, Laquandra Nesbitt

    A multi-disciplinary panel of health officials and academic leaders graded current efforts to address health disparities as mixed, noting that while national perception has shifted to view these gaps as systemic societal failures, tangible progress remains slow due to a continued reliance on individual behavior change rather than structural interventions. The discussion identified economic inequality, provider homogeneity, and profit-driven resource consolidation as primary drivers of the disparity gap, particularly in Washington D.C. where high medical density fails to bridge the massive income divide between wards. To rectify these issues, experts proposed establishing dedicated health equity offices, adopting community-led prioritization frameworks to prevent research extraction, and redirecting public resources like the Housing Trust Fund to avoid spatially concentrating poverty.

  14. Milken Institute51 min

    Toward a Healthier Workplace: The Business Case for Public Health

    Ryan Shadrick Wilson, John Agwunobi, Steve Burd, Jeffrey Levi, Mark Wagar

    A panel of industry leaders including Steve Bird, representing Safeway and Herbalife, advocates for a strategic shift from participation-based wellness to outcome-driven healthcare models to address the trillion-dollar burden of chronic diseases. These organizations demonstrate that linking premium incentives directly to health results can significantly lower obesity rates and improve chronic disease management while simultaneously reducing turnover and fostering community-wide health culture. The consensus emphasizes that sustainable reform requires decoupling care from fee-for-service payment structures, investing in early prevention, and creating a supportive ecosystem that extends from the workplace into the broader community.

  15. Milken Institute47 min

    The Economic Impact of Chronic Disease

    Ross DeVol, Nancy Brown, Neal Kaufman, Kristen Miranda, Hugh Waters, Otis Webb Brawley

    The Milken Institute convened health leaders and researchers to address the escalating economic and human toll of chronic diseases, emphasizing that 80% of cardiovascular conditions and rising cancer rates are preventable through lifestyle changes and systemic reform. Speakers highlighted stark disparities linked to education and income while detailing how policy interventions, such as Medicaid expansion and Accountable Care Organizations, can reduce waste and improve early detection. The session concluded with a unified call to shift from fee-for-service models to patient-centric strategies that leverage digital tools and early education to extend healthy life years rather than merely treating illness.