Latest Interviews
Showing 16–30 of 33 transcripts.
Clear all filters- All-In Podcast1h 37m
Trump's Big Week: Middle East Trip, China Deal, Pharma EO, "Big, Beautiful Bill" with Ben Shapiro
Trump, Ben Shapiro, Phil Hellmuth, Jason Calacanis, Chamath Palihapitiya, David Friedberg, David Sacks
Hosts Jason Calacanis, Chamath Palihapitiya, and Ben Shapiro issued a formal apology to poker legend Phil Hellmuth for previously making false claims about his relationship with Timothée Chalamet and his status among Hollywood elites. Concurrently, the discussion detailed President Trump's Middle East trip, which secured approximately $2 trillion in investment deals while signaling a foreign policy shift toward commerce over interventionism. The panel also examined domestic issues including a proposed tax bill projected to add $4.1 trillion to the deficit, state bans on cellular meat, and an executive order aiming to slash pharmaceutical prices by 30 to 80 percent through a "Most Favored Nation" mechanism.
- All-In Podcast2h 2m
The Great Tariff Debate with David Sacks, Larry Summers, and Ezra Klein
David Sacks, Larry Summers, Ezra Klein, Friedberg, Jason Calacanis, Chamath Palihapitiya
On the eighty-day mark of President Trump's second term, the administration paused reciprocal tariffs to force global negotiations while enforcing a 125% hike on China, triggering historic market volatility and a cumulative $6 trillion loss since "Liberation Day." Critics like Larry Summers and Ezra Klein warn that this erratic "Peron-style" governance and the DOGE initiative's aggressive austerity measures risk destroying essential state capacity and triggering a deep recession, while proponents such as David Sacks and Chamath Palihapitiya defend the chaotic strategy as necessary game theory to secure onshoring of critical technologies and reset trade frameworks.
- All-In Podcast1h 39m
Fixing the American Dream with Andrew Schulz
Andrew Schulz, Friedberg, Gavin Newsom, Trump, Jason Calacanis
In a May 3 Miami event featuring comedian Andrew Schulz, hosts Jason Calacanis and David Sack discussed advanced IVF technologies, the strategic implications of Governor Gavin Newsom's new podcast, and critiques of President Trump's tariff policies. The dialogue extended to economic solutions such as investing the Social Security Trust Fund in equities to prevent 2032 insolvency, while analyzing housing market distortions and the psychological drivers behind modern conspiracy theories. Panelists also shared personal investment origins, evaluated the Department of Government Efficiency's potential under Elon Musk, and highlighted JD Vance's political trajectory as a key figure in future American leadership.
- All-In Podcast1h 15m
Epstein Files Flop, State of the Market, Autonomous Robots, Trump's Gold Card, Friedberg on Jeopardy
Trump, Friedberg, Chamath, Bezos, Jason Calacanis, David Sacks
In a recent episode, hosts Jason Calacanis, Chamath Palihapitiya, and David Freiberg discussed a wide range of topics including David Freiberg's $1 million *Celebrity Jeopardy!* victory and Brett Atcock's accelerated timeline for home robot beta tests by late 2025. The conversation shifted to macroeconomic concerns, with Freiberg warning of stagflation due to tariffs and immigration policies while analyzing the $91.5 billion valuation of payment giant Stripe against its competitor Adyen. Additionally, the panel debated Donald Trump's proposed $5 million "Golden Visa" program and the strategic implications of dissolving the USPS governing board to improve economic data collection.
- All-In Podcast1h 46m
The Stablecoin Future, Milei's Memecoin, DOGE for the DoD, Grok 3, Why Stripe Stays Private
Milei, Patrick Collison, Jamie Dimon, Trump, Elon, Jason Calacanis, David Friedberg
Stripe leaders Patrick and John Collison, joined by Chamath Palihapitiya and Dave Sacks, discussed the company's $1 trillion annual processing volume, its strategic pivot into stablecoin infrastructure via the Bridge acquisition, and its continued decision to remain private to prioritize long-term compounding. The panel also critiqued recent political missteps, such as Javier Milei's meme coin failure, while highlighting the ARC Institute's release of the Evo 2 biological AI model and Elon Musk's rapid Grok 3 training via the "Colossus" data center initiative. Finally, the conversation addressed shifting geopolitical defense strategies, the ongoing risks of asteroid 2024 YR4, and the broader impact of remote work policies on early-career professional development.
- All-In Podcast1h 10m
DOGE unveils a roadmap, Unlocking GDP Growth, WW3 escalation, Fat cell memory
Chamath, Friedberg, Jason Calacanis, David Sacks
Elon Musk and Vivek Ramaswamy's Department of Government Efficiency plans to eliminate $500 billion in unauthorized federal spending over an 18-month period by leveraging recent Supreme Court rulings to bypass traditional legislative approval processes. The initiative targets regulatory rollbacks through executive audits and temporary payment suspensions while facing anticipated legal challenges from entrenched bureaucratic interests and internal Republican resistance to deficit reduction. Concurrently, the discussion highlights global security risks regarding Western missile capabilities in the Ukraine-Russia conflict and presents scientific breakthroughs in epigenetics that explain persistent obesity mechanisms despite weight loss.
- All-In Podcast1h 23m
Trump's market impact: Bitcoin, M&A, IPOs + transition picks; Polymarket CEO raided by FBI
Trump, Shayne Coplan, Chamath Palihapitiya, David Sacks, Jason Calacanis
Amidst a crypto market surge where Bitcoin neared $92,000, hosts Chamath Palihapitiya and David Sacks analyzed Trump's emerging crypto policies, including potential regulatory shifts and a strategic Bitcoin reserve, while noting the broader market's sensitivity to persistent inflation and Treasury yields. The discussion extended to the incoming administration's cabinet lineup, highlighting appointments like Bobby Kennedy Jr. and Matt Gaetz as catalysts for an "extinction event" within federal agencies, alongside a critical look at tech regulation and the impending IPO landscape for major firms like Stripe and Databricks. Furthermore, the guests examined the convergence of political and financial markets through the lens of the recent Polymarket FBI raid and the changing dynamics of broadcast media, ultimately warning that unintended geopolitical escalation remains the most significant risk for the coming term.
- All-In Podcast2h 12m
In conversation with Reid Hoffman & Robert F. Kennedy Jr.
Reid Hoffman, Robert F. Kennedy Jr., Sacks, Jay Cowell, Jason Calacanis, David Friedberg, Chamath Palihapitiya
Tech leaders including Reid Hoffman, David Sacks, and Chamath Palihapitiya discussed NVIDIA's projected transition from training to inference chips and OpenAI's corporate governance while criticizing FTC antitrust policies for stifling venture capital exits. The panelists also engaged in contentious debates over the 2024 US election, analyzing the Democratic Party's pivot to Kamala Harris and Robert F. Kennedy Jr.'s strategic alliance with Donald Trump on issues like the Ukraine war and censorship. Finally, the group examined systemic health crises attributed to industrial food subsidies and regulatory capture, contrasting conspiracy-driven narratives with market incentive explanations.
- All-In Podcast1h 19m
Kamala surges, Trump at NABJ, recession fears, Middle East escalation, Ackman postpones IPO
Kamala, Trump, Ackman, Chamath, Friedberg, Ismail Haniyeh, Harris, Netanyahu, Grdecter, David Sacks, Jason Calacanis
Nate Silver's latest model projects a narrow electoral path for Kamala Harris despite Donald Trump leading the Electoral College, a race that commentators attribute to a "snapback" of anti-Biden voters while critics argue her strategy lacks authenticity due to an over-reliance on scripted messaging. The panel further debates macroeconomic stability, with David Sacks and Chamath Palihapitiya warning that current GDP growth is artificially inflated by unsustainable government spending and that the AI sector faces a deflationary reset as infrastructure costs fail to yield immediate returns. Geopolitical risks loom large following the Mossad assassination of an Iranian Hamas leader, which has heightened fears of a regional escalation that could destabilize global markets alongside the impending Federal Reserve interest rate decision.
- All-In Podcast1h 25m
DOJ targets Nvidia, Meme stock comeback, Trump fundraiser in SF, Apple/OpenAI, Texas stock market
Trump, Chamath, Keith Gill, Roaring Kitty, Jason Calacanis, David Friedberg
Hosts of the "All In" podcast sparked a debate with Vinod Khosla over accusations of elitism while warning that a hostile regulatory environment regarding antitrust, crypto, and M&A may drive Silicon Valley toward the GOP. The conversation also examined the Democratic Party's declining support among working-class voters, speculating on a potential replacement for President Biden and predicting a surge of tech figures pivoting to Trump. In market developments, the panel analyzed the surge in GameStop trading, proposed competition for the NYSE and Nasdaq through a new Texas Stock Exchange, and discussed a strategic Apple-OpenAI partnership to revitalize the iPhone upgrade cycle.
- All-In Podcast1h 41m
GPT-4o launches, Glue demo, Ohalo breakthrough, Druck's Argentina bet, did Google kill Perplexity?
Phil Hellmuth, Friedberg, Stanley Druckenmiller, Javier Milei, Chamath Palihapitiya, David Sacks, Jason Calacanis
Hosts Chamath Palihapitiya, Jason Calacanis, David Sacks, and Freddie Friedberg discuss the launch of OpenAI's GPT-4o, Google's AI Overviews, and Sacks' agricultural breakthrough Ohalo Genetics, which uses boosted breeding to double crop yields. The episode further details significant investment updates, including $2 million raised for Ohalo, Calacanis's stake in AI training service Athena Wow, and Stanley Druckenmiller's pivot to the Argentine market following Javier Milei's election. Throughout the conversation, the group analyzes macroeconomic trends in the US and Argentina while predicting that basic AI capabilities will become standard infrastructure, fundamentally reshaping enterprise software and agricultural productivity within two years.
- All-In Podcast1h 43m
Sam Altman: Getting Fired (and Re-Hired) by OpenAI, Agents, AI Copyright issues
Sam Altman, Chamath, Friedberg, Jason Calacanis, David Sacks
Sam Altman outlined OpenAI's strategy to prioritize widespread accessibility of advanced AI and international safety governance while navigating hardware constraints and evolving intellectual property frameworks. The discussion detailed a shift toward specialized model architectures for scientific discovery, the complexities of the November 2023 leadership transition, and speculation on new hardware partnerships with Apple. Ultimately, the event emphasized a vision where artificial general intelligence transforms healthcare and scientific research through rapid, low-cost computation and rigorous global oversight.
- All-In Podcast1h 15m
Sheryl Sandberg, plus open-source AI gene editing explained
Sheryl Sandberg, Dave Goldberg, Chamath, Friedberg, TheZachEffect, Jason Calacanis, David Sacks
Hosts Chamath Palihapitiya, Jason Calacanis, and David Sacks interview Sheryl Sandberg about her documentary *Screams Before Silence*, which utilizes survivor testimony to combat denialism regarding sexual violence committed by Hamas on October 7th while critiquing the silence of feminist organizations and university policies. The conversation also pivots to Profluent Bio's open-sourced AI-designed gene editing tool, Open CRISPR-1, which the hosts argue could democratize biotechnology by bypassing restrictive intellectual property landscapes and accelerating innovation in life sciences. Throughout the episode, the hosts balance a tribute to the late Dave Goldberg with substantive debates on war crimes documentation and the economic potential of open-source biological models.
- All-In Podcast1h 4m
#AIS: Palmer Luckey on Anduril
Palmer Luckey, Jason Calacanis, Zach, Kara Swisher, Austin Peter Smith, Ian Thompson
Anduril founder Palmer Luckey defends his career and critiques the U.S. defense industry's reliance on legacy contractors and Silicon Valley's ideological resistance to modernizing military technology. The speech details Luckey's personal grievances against Jason Calacanis regarding past accusations of moral failings while outlining Anduril's strategy to deploy autonomous systems in response to geopolitical threats from China and Russia. Despite the tense confrontation, both parties conclude the dialogue by affirming their shared commitment to American national security and the strategic necessity of integrating commercial innovation into defense capabilities.
- Lex Fridman2h 11m
Jason Calacanis: Startups, Angel Investing, Capitalism, and Friendship | Lex Fridman Podcast #161
Jason Calacanis recounts his pivotal angel investment in Robinhood and the subsequent GameStop saga to illustrate a generation of retail traders challenging institutional power while exposing systemic market opacity. He expands the discussion to a global analysis of capitalism versus authoritarianism, emphasizing that entrepreneurial risk and the ability to "learn how to learn" are critical for survival against China's state-capitalist model. Ultimately, Calacanis advocates for a return to fierce loyalty, human connection, and radical responsibility in leadership as the antidote to societal "softness" and the inevitable volatility of high-growth ventures.