Latest Interviews
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Clear all filters- Milken Institute48 min
Building Mental Health Resilience at Each Stage of Life
Melissa Stevens, Cynthia Germanotta, Joshua Gordon, Howard Spivak, Nora Super, Jennifer Velez
A comprehensive panel of researchers, clinicians, and patients addressed the U.S. mental health crisis as a "wicked problem," highlighting that social determinants account for 70% of health outcomes while genetic and early-life stress factors significantly influence biological aging and resilience. The discussion underscored the urgent need to bridge the massive care gap for youth through digital therapeutics, collaborative care models, and policy reforms that integrate non-clinical support with traditional treatment to mitigate a $400 billion annual economic drag. Experts called for a systemic shift toward preventative strategies and stigma reduction, arguing that treating mental illness with the same biological equivalence as chronic physical conditions is essential for improving functional wellness across all life stages.
- Milken Institute29 min
A Conversation with Francis Collins, Director, National Institutes of Health
Francis Collins, Meg Tirrell, Richard Ditizio, Synim Rivers
The event highlights a critical gender and racial leadership gap in healthcare, where women comprise half the workforce but hold only 3% of CEO roles, prompting organizations like Horizon Pharma to sign diversity pledges and adopt business resource groups to drive financial and clinical innovation. Parallel to these corporate initiatives, the NIH's "All of Us" research program and the Brain Initiative are launching large-scale, data-driven efforts to individualize medicine and accelerate cures for Alzheimer's and other neurological conditions by mapping billions of neurons and enrolling a diverse cohort of one million participants. These combined strategies aim to transform healthcare from a one-size-fits-all model into a precision-based system supported by robust funding, emerging gene therapies for sickle cell disease, and immunotherapy breakthroughs for metastatic cancers.
- Milken Institute1h 1m
System Thinking to Drive Patient Engagement: Walking the Talk
Susan Schaeffer, Julie Gerberding, Ivor Horn, Kathy Hudson, Bray Patrick-Lake, Janet Woodcock, Arthur Allen, Syra
Regulatory leaders, including FDA Director Janet Woodcock, and biopharmaceutical executives like Merck's Julie Gerberding discussed how the 21st Century Cures Act and PDUFA reauthorizations have institutionalized patient input to reshape drug development protocols. Panelists highlighted that early engagement reduces costly trial amendments while shifting metrics from clinical markers to patient-reported outcomes, as evidenced by approvals for conditions like multiple sclerosis and Duchenne muscular dystrophy. Despite challenges regarding diversity and internal cultural shifts, the consensus emphasizes that integrating lived experience into benefit-risk assessments accelerates innovation and aligns industry practices with patient needs.
- Milken Institute58 min
Women's Health: Addressing Disparities from Health Leadership to Patient Care
Joanne Kenen, Janine Austin Clayton, Isabella Danel, Freda Lewis-Hall, Saralyn Mark, Paula Schneider
A panel of high-level health leaders from Pfizer, NIH, and the Susan G. Komen foundation highlighted the persistent gap between women's 57% share of U.S. healthcare expenses and their underrepresentation as decision-makers in clinical research. Participants argued that moving beyond a narrow reproductive focus to a holistic model addressing social determinants like violence and poverty requires integrating sex and gender data into all phases of biomedical innovation, from drug trials to medical device design. The group concluded that achieving equity demands structural changes, including formal male sponsorship, expanded parental leave, and the adoption of gendered innovations to ensure health systems serve diverse populations effectively.
- Milken Institute57 min
Confronting the Obesity and Diabetes Epidemics
William Dietz, Kelly Close, Sean Duffy, Mark Hyman, Joshua Riff, Hugh Waters
This panel addresses the $3.4 trillion annual economic burden of chronic diseases in the U.S., where obesity drives nearly half the costs and disproportionately affects underserved populations through a broken primary care capacity. Experts from organizations like Cleveland Clinic, Omada, and OnDuo demonstrated that community-based food pharmacy models and digital health platforms can dramatically reverse conditions like diabetes and heart failure while reducing costs by up to 80%. To scale these life-saving interventions, the discussion emphasized an urgent need to shift from episodic "sick care" to value-based reimbursement systems that fund "food as medicine" and community health workers.
- Milken Institute1h 0m
Regulating Medical Innovation in the Digital Age
Lisa Suennen, William Carson, Aneesh Chopra, Sohini Chowdhury, Lucia Savage, Jeffrey Shuren, Lisa Sunin, Jeff Sheeran, Bill Carson
A panel of industry leaders and FDA officials analyzed the surge in digital healthcare investment, which has exceeded $40 billion, while addressing regulatory hurdles that slow the development of Software as a Medical Device. Key discussions highlighted the FDA's "Pre-Cert" pilot program and the critical need for interoperability standards like FHIR to reduce data costs and overcome fragmentation in telemedicine and direct-to-consumer markets. Despite breakthroughs such as the first digital medicine approval, experts emphasized that legacy frameworks struggle to accommodate rapid software iteration, opaque deep learning algorithms, and complex data privacy requirements across 57 state and federal jurisdictions.
- Milken Institute34 min
A Conversation with Scott Gottlieb, Commissioner, U.S. Food and Drug Administration
Scott Gottlieb, Tanisha Carino, Michael Milken
The FDA is implementing a comprehensive strategic shift to accelerate drug approvals through digital health integration, organizational restructuring within the Office of New Drugs, and a transition to risk-based, post-market regulation for digital tools and manufacturing. This initiative aims to increase review productivity by 20%, publish hundreds of new guidances, and release detailed approval memos within 48 hours to enhance transparency while addressing pipeline disparities in rare versus common diseases. Concurrently, the agency prioritizes tobacco control through modified risk products and fosters market competition to lower drug costs, with Commissioner Gottlieb warning that ossified reimbursement models for novel therapies threaten future innovation if not adapted.
- Milken Institute57 min
Race, Gender, and Work: The Economics of Healthy Aging
Patricia (Pat) Milligan, William Dow, Sarita Gupta, Cara James, Lisa Margeson, Debra Whitman
A comprehensive analysis of systemic inequalities reveals that women face significant wealth and health disadvantages driven by caregiving burdens, racial disparities, and labor force interruptions that cost the average female caregiver $300,000 in lost benefits. While structural barriers like age discrimination and a cultural silence on personal finance exacerbate these gaps, progressive policy interventions such as Hawaii's Kāpūna Caregiver Program and Washington's Long-Term Care Trust Act are beginning to revalue unpaid care work. Economic experts and major corporations now advocate for universal family care insurance and expanded paid leave to normalize caregiving across genders and close the persistent wealth gap.
- Milken Institute58 min
Loneliness as a Risk Factor: Making Connections to Improve Health
Lisa Marsh Ryerson, Lynn Goldman, Sachin Jain, Jeremy Nobel, Anand Parekh, Brian Van Buren, Phyllis Foxworth, Satya
Experts, healthcare leaders, and policymakers convened to address the rising epidemic of loneliness and social isolation, which carry mortality risks comparable to smoking and exacerbate syndemics with obesity and addiction. The discussion highlighted disproportionate impacts on marginalized groups, such as LGBTQ elders and rural communities, while showcasing successful business models like CareMore Health's social prescriptions that have driven a 75% increase in patient engagement. Strategic recommendations included adopting national screening metrics, integrating connection into value-based care, and deploying human-centered interventions to mitigate the $7 billion annual Medicare burden and reverse declining life expectancy.
- Milken Institute1h 6m
A Conversation with Dan Gilbert
The provided text lacks coherent facts, specific figures, or actionable outcomes, rendering it impossible to generate a substantive summary of any specific event. While the content vaguely references topics such as a "30-year" work history, the University of Washington, and a "2011 special case study" in San Diego, these elements appear in a fragmented and unverified context. Consequently, no meaningful description of key figures or results can be constructed without fabricating data not present in the source material.
- Milken Institute1h 1m
Creating a Culture of Biomedical Innovation
Mike Rea, Christopher Austin, Amitabh Chandra, Margaret Hamburg, Jennifer Miller, Jason Spangler
A cross-sector panel comprising leaders from NCATS, the FDA, Harvard, and Amgen redefined biomedical innovation as a value-driven process that balances patient outcomes with accessibility and ethical trust. By advocating for a collaborative culture that normalizes failure and breaks down silos between research, regulation, and reimbursement, the group proposed shifting metrics from simple speed to societal acceleration and integrity. The discussion ultimately highlighted critical misalignments in R&D funding, noting that commercial incentives currently neglect major disease burdens like mental health and neglected tropical diseases, necessitating a structural shift toward public-sector leadership.
- Milken Institute1h 4m
Digital Health Technology and Solutions
Steven Krein, Katie Agarwal, Matthew Stoudt, Sara Wajnberg, Joel White, Sarah Weinberg, John Birch, George Masregas, Lucia Savage, Hoyt Morgan, Paul Anthony, Lisa Fitzpatrick, Mike Goodman
The event convened leaders from Oscar Insurance, Maven Clinic, Applied VR, and Horizon Government Affairs to analyze how converging macro trends and $10 trillion in capital are reshaping global digital health. Despite rapid venture investment, the panel highlighted critical barriers including fragmented state licensing, stagnant Medicare reimbursement, and misaligned regulatory frameworks that force startups to pivot from consumer to employer models. Looking ahead, the industry aims to drive individualization and equity through unified data standards, risk-based FDA pre-certification, and cross-sector collaboration to eliminate friction in chronic pain management and women's health care.
- Milken Institute56 min
Mind and Body: Workplace Wellness
Stephen Sokoler, Kelley Vargo, Rachel Goldstein
Kelly Vargo and Steven Sockler presented evidence that integrating simple physical movements and mindfulness practices into the workplace significantly reduces global mortality risks and boosts organizational ROI through reduced absenteeism and increased productivity. Vargo advocated for the "Health 401K" concept using chair-based exercises and standing triggers, while Sockler detailed how meditation expands the prefrontal cortex and generates substantial financial savings, as demonstrated in case studies from Aetna and Humana. The session concluded that successful implementation relies on visible senior leadership modeling these behaviors to drive cultural change and utilizing data to secure executive buy-in for long-term wellness initiatives.
- Milken Institute1h 0m
Brain Health for Longevity: What Works? What Doesn't?
Nora Super, Alvaro Fernandez, Sarah Lock, David Perlmutter, Alfred Sandrock, Brian Van Buren, Jeff Wilkinson, Dr. Mark Hyman, Joe Maroon, Mark Fisher
Amidst a rapidly aging U.S. population where one in five residents will be over 65 by 2030, this event examines the convergence of biological mechanisms like autophagy and clinical breakthroughs to address the $716 trillion economic impact of cognitive decline. Panelists discuss a critical shift from late-stage treatment to early prevention, detailing how multimodal interventions—including sleep optimization, vascular health management, and disease-modifying therapies in the DIAN trial—can delay dementia onset by five to ten years. The discussion further emphasizes the necessity of overcoming diagnostic stigma and equity gaps to integrate neurotechnology and community support systems into a comprehensive public health strategy for brain longevity.
- Milken Institute57 min
Reimagining Medicare for Longer Lives
Joanne Kenen, Efrem Castillo, Nancy-Ann DeParle, Terry Fulmer, Darilyn Moyer, John, Saira, Corinne Purtill
This panel discussion analyzes the structural misalignment between the US healthcare system's acute-care origins and the modern demographic reality of an aging population living longer with chronic conditions. While bipartisan legislation and private sector innovations in Medicare Advantage are successfully shifting incentives toward value-based care and addressing social determinants, implementation is severely hindered by astronomical administrative burdens and fragmented health IT interoperability. Participants conclude that future progress requires integrating social services into medical models and leveraging private sector experimentation to streamline the transition away from volume-based reimbursement.