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  1. Milken Institute1h 0m

    Regulating Medical Innovation in the Digital Age

    Lisa Suennen, William Carson, Aneesh Chopra, Sohini Chowdhury, Lucia Savage, Jeffrey Shuren, Lisa Sunin, Jeff Sheeran, Bill Carson

    A panel of industry leaders and FDA officials analyzed the surge in digital healthcare investment, which has exceeded $40 billion, while addressing regulatory hurdles that slow the development of Software as a Medical Device. Key discussions highlighted the FDA's "Pre-Cert" pilot program and the critical need for interoperability standards like FHIR to reduce data costs and overcome fragmentation in telemedicine and direct-to-consumer markets. Despite breakthroughs such as the first digital medicine approval, experts emphasized that legacy frameworks struggle to accommodate rapid software iteration, opaque deep learning algorithms, and complex data privacy requirements across 57 state and federal jurisdictions.

  2. Milken Institute34 min

    A Conversation with Scott Gottlieb, Commissioner, U.S. Food and Drug Administration

    Scott Gottlieb, Tanisha Carino, Michael Milken

    The FDA is implementing a comprehensive strategic shift to accelerate drug approvals through digital health integration, organizational restructuring within the Office of New Drugs, and a transition to risk-based, post-market regulation for digital tools and manufacturing. This initiative aims to increase review productivity by 20%, publish hundreds of new guidances, and release detailed approval memos within 48 hours to enhance transparency while addressing pipeline disparities in rare versus common diseases. Concurrently, the agency prioritizes tobacco control through modified risk products and fosters market competition to lower drug costs, with Commissioner Gottlieb warning that ossified reimbursement models for novel therapies threaten future innovation if not adapted.

  3. Milken Institute57 min

    Race, Gender, and Work: The Economics of Healthy Aging

    Patricia (Pat) Milligan, William Dow, Sarita Gupta, Cara James, Lisa Margeson, Debra Whitman

    A comprehensive analysis of systemic inequalities reveals that women face significant wealth and health disadvantages driven by caregiving burdens, racial disparities, and labor force interruptions that cost the average female caregiver $300,000 in lost benefits. While structural barriers like age discrimination and a cultural silence on personal finance exacerbate these gaps, progressive policy interventions such as Hawaii's Kāpūna Caregiver Program and Washington's Long-Term Care Trust Act are beginning to revalue unpaid care work. Economic experts and major corporations now advocate for universal family care insurance and expanded paid leave to normalize caregiving across genders and close the persistent wealth gap.

  4. Milken Institute58 min

    Loneliness as a Risk Factor: Making Connections to Improve Health

    Lisa Marsh Ryerson, Lynn Goldman, Sachin Jain, Jeremy Nobel, Anand Parekh, Brian Van Buren, Phyllis Foxworth, Satya

    Experts, healthcare leaders, and policymakers convened to address the rising epidemic of loneliness and social isolation, which carry mortality risks comparable to smoking and exacerbate syndemics with obesity and addiction. The discussion highlighted disproportionate impacts on marginalized groups, such as LGBTQ elders and rural communities, while showcasing successful business models like CareMore Health's social prescriptions that have driven a 75% increase in patient engagement. Strategic recommendations included adopting national screening metrics, integrating connection into value-based care, and deploying human-centered interventions to mitigate the $7 billion annual Medicare burden and reverse declining life expectancy.

  5. Milken Institute1h 6m

    A Conversation with Dan Gilbert

    Dan Gilbert, Michael Milken

    The provided text lacks coherent facts, specific figures, or actionable outcomes, rendering it impossible to generate a substantive summary of any specific event. While the content vaguely references topics such as a "30-year" work history, the University of Washington, and a "2011 special case study" in San Diego, these elements appear in a fragmented and unverified context. Consequently, no meaningful description of key figures or results can be constructed without fabricating data not present in the source material.

  6. Milken Institute1h 1m

    Creating a Culture of Biomedical Innovation

    Mike Rea, Christopher Austin, Amitabh Chandra, Margaret Hamburg, Jennifer Miller, Jason Spangler

    A cross-sector panel comprising leaders from NCATS, the FDA, Harvard, and Amgen redefined biomedical innovation as a value-driven process that balances patient outcomes with accessibility and ethical trust. By advocating for a collaborative culture that normalizes failure and breaks down silos between research, regulation, and reimbursement, the group proposed shifting metrics from simple speed to societal acceleration and integrity. The discussion ultimately highlighted critical misalignments in R&D funding, noting that commercial incentives currently neglect major disease burdens like mental health and neglected tropical diseases, necessitating a structural shift toward public-sector leadership.

  7. Milken Institute1h 4m

    Digital Health Technology and Solutions

    Steven Krein, Katie Agarwal, Matthew Stoudt, Sara Wajnberg, Joel White, Sarah Weinberg, John Birch, George Masregas, Lucia Savage, Hoyt Morgan, Paul Anthony, Lisa Fitzpatrick, Mike Goodman

    The event convened leaders from Oscar Insurance, Maven Clinic, Applied VR, and Horizon Government Affairs to analyze how converging macro trends and $10 trillion in capital are reshaping global digital health. Despite rapid venture investment, the panel highlighted critical barriers including fragmented state licensing, stagnant Medicare reimbursement, and misaligned regulatory frameworks that force startups to pivot from consumer to employer models. Looking ahead, the industry aims to drive individualization and equity through unified data standards, risk-based FDA pre-certification, and cross-sector collaboration to eliminate friction in chronic pain management and women's health care.

  8. Milken Institute56 min

    Mind and Body: Workplace Wellness

    Stephen Sokoler, Kelley Vargo, Rachel Goldstein

    Kelly Vargo and Steven Sockler presented evidence that integrating simple physical movements and mindfulness practices into the workplace significantly reduces global mortality risks and boosts organizational ROI through reduced absenteeism and increased productivity. Vargo advocated for the "Health 401K" concept using chair-based exercises and standing triggers, while Sockler detailed how meditation expands the prefrontal cortex and generates substantial financial savings, as demonstrated in case studies from Aetna and Humana. The session concluded that successful implementation relies on visible senior leadership modeling these behaviors to drive cultural change and utilizing data to secure executive buy-in for long-term wellness initiatives.

  9. Milken Institute1h 0m

    Brain Health for Longevity: What Works? What Doesn't?

    Nora Super, Alvaro Fernandez, Sarah Lock, David Perlmutter, Alfred Sandrock, Brian Van Buren, Jeff Wilkinson, Dr. Mark Hyman, Joe Maroon, Mark Fisher

    Amidst a rapidly aging U.S. population where one in five residents will be over 65 by 2030, this event examines the convergence of biological mechanisms like autophagy and clinical breakthroughs to address the $716 trillion economic impact of cognitive decline. Panelists discuss a critical shift from late-stage treatment to early prevention, detailing how multimodal interventions—including sleep optimization, vascular health management, and disease-modifying therapies in the DIAN trial—can delay dementia onset by five to ten years. The discussion further emphasizes the necessity of overcoming diagnostic stigma and equity gaps to integrate neurotechnology and community support systems into a comprehensive public health strategy for brain longevity.

  10. Milken Institute57 min

    Reimagining Medicare for Longer Lives

    Joanne Kenen, Efrem Castillo, Nancy-Ann DeParle, Terry Fulmer, Darilyn Moyer, John, Saira, Corinne Purtill

    This panel discussion analyzes the structural misalignment between the US healthcare system's acute-care origins and the modern demographic reality of an aging population living longer with chronic conditions. While bipartisan legislation and private sector innovations in Medicare Advantage are successfully shifting incentives toward value-based care and addressing social determinants, implementation is severely hindered by astronomical administrative burdens and fragmented health IT interoperability. Participants conclude that future progress requires integrating social services into medical models and leveraging private sector experimentation to streamline the transition away from volume-based reimbursement.

  11. Milken Institute56 min

    Health-care Disruptors: New Models Changing the Landscape

    Casey Ross, Ray Dorsey, Joel Dudley, Andrea Feinberg, Dan Liljenquist

    A multidisciplinary panel led by Dr. Ray Dorsey, Dan Liljenquist, Dr. Andrea Feinberg, and Dr. Joel Dudley addressed critical healthcare failures, highlighting how telemedicine, generic drug shortages, nutritional interventions, and data fragmentation impact patient outcomes and system efficiency. The speakers detailed successful pilot programs, including University of Rochester's home-based Parkinson's care, CivicaRx's nonprofit generic manufacturing model, Geisinger's Fresh Food Pharmacy, and Mount Sinai's data-driven precision health initiatives, all of which demonstrated significant reductions in costs and mortality. Despite these proven efficacy metrics, the discussion underscored that widespread scalability remains constrained by rigid Medicare reimbursement policies, regulatory limits on social determinants of care, and fragmented data infrastructure that prevents algorithmic integration.

  12. Milken Institute59 min

    Finding a Cure for the Cost of Durable Therapies

    Dan Mendelson, Yvonne Greenstreet, Joe Grogan, Michael Sherman, Mark Skinner, John Birch, Ian Kramer, Jupiter Lazmar

    A panel of industry leaders, payers, and advocates highlighted the systemic friction between transformative gene therapies and traditional commercial models that rely on high-volume patient pools to amortize R&D costs. Participants detailed pricing pressures for one-time cures and chronic durable treatments while showcasing innovative risk-sharing agreements, such as Alnylam's outcomes-based pilot with Harvard Pilgrim Health Care, to manage financial exposure. Addressing these challenges, the group called for federal policy reform to eliminate "best price" disincentives and the adoption of flexible valuation frameworks that integrate patient-reported outcomes to prevent insurance affordability crises.

  13. Milken Institute36 min

    Addressing Social Determinants to Improve Health Outcomes

    Anand Parekh, Karen DeSalvo, Esther Dyson, Sergio Matos, Alan Moses, Lydia, Mark Hyman, Helen

    Former health officials and community leaders convened to argue that social determinants like housing and food security drive 80% of health outcomes, citing Humana and CMS data where interventions yielded significant cost savings and improved well-being. Despite evidence supporting community health workers and local partnerships, the panel identified rigid funding structures, actuarial caution, and an overreliance on randomized trials as primary barriers to mainstreaming these models. Strategic recommendations include integrating social factors into Medicaid reimbursement, shifting from short-term grants to sustainable community ownership, and redefining health as a systemic design issue rather than a purely clinical one.

  14. Milken Institute59 min

    Food is Medicine

    Allison Aubrey, Tom Crohan, Wendy Johnson, Jason Karp, Dariush Mozaffarian, Greg Barrett, Terry

    Addressing the global obesity and diabetes pandemic, a panel of experts from Tufts, Nestlé, John Hancock, and Torbillon discussed the paradox of rising chronic disease rates amidst growing consumer interest in "clean food." Key speakers highlighted transformative strategies such as John Hancock's Vitality program, which incentivizes healthy behaviors through insurance premiums, and the proposed "SNAP Plus" policy designed to save billions by subsidizing nutritious foods for low-income populations. Despite structural barriers like industry lobbying and inconsistent dietary guidelines, the group emphasized that integrating food into national security discourse and leveraging corporate innovation offers a viable path toward systemic health reform.

  15. Milken Institute58 min

    Opioid Crisis: Examining National, State, and Local Responses and Impact

    Dan Diamond, Shereef Elnahal, Thomas Graf, Elinore McCance-Katz, Nora Volkow

    At the Milken Institute Future of Health Summit, federal and state leaders including Dr. Nora Volkow, Dr. Eleanor McCance-Katz, and Dr. Sharif El-Nahal convened with insurer representatives to address the heterogeneous nature of the opioid crisis through a multi-trajectory approach. The panelists detailed concrete strategies such as New Jersey's integration of medication-assisted treatment in correctional facilities, Horizon Blue Cross's shift away from non-evidence-based urine testing, and SAMHSA's efforts to mainstream addiction training in medical schools. Consensus emerged that sustainable outcomes require granular real-time data infrastructure and collaborative partnerships that empower local communities with the flexibility to tailor interventions to specific demographic and geographic needs.