Latest Interviews
Showing 91–105 of 316 transcripts.
Clear all filters- All-In Podcast11 min
Bryan Johnson’s Best Health Hack: Lower Your RHR Before Sleep = Sleep Better and Live Longer
Brian Johnson presents an ambitious framework positioning the indefinite extension of human life as a new global ideology, utilizing biological age testing to illustrate that organs age independently and require targeted management. He identifies resting heart rate as the primary health metric and details a specific protocol involving strict sleep hygiene, diet timing, and screen discipline to lower this rate by approximately 10%. This approach aims to reverse aging trends while simultaneously treating sleep as the fundamental intervention for anxiety and depression, ultimately preparing humanity for a future defined by superintelligence.
- All-In Podcast19 min
Cathie Wood on How AI Can Double GDP, Bull Case for Bitcoin $1M, Elon’s Trillion-Dollar Pay Package
ARK Capital projects a near-future US GDP acceleration to 7% driven by the convergence of five innovation platforms, a trajectory that investor Cathie Wood attributes to both technological deflation and the Trump administration's tax policies. The firm forecasts a significant market broadening away from the "Mag 6" toward disruptive sectors like autonomous mobility and multi-omic healthcare, with a targeted 40–50% compound annual return for innovation equities over the next five years. Supporting this thesis, ARK maintains a bullish $2,600 price target for Tesla and a valuation model suggesting Bitcoin could reach $3.8 million, while advocating for regulatory reforms to expand private market access to retail investors.
- All-In Podcast28 min
Sequoia’s Roelof Botha: Why Venture Capital is Broken & How Great Companies Are Built
Sequoia Capital, led by a third generation of partners, sustains its legacy by prioritizing long-term value creation and consensus decision-making over aggressive fee maximization. The firm counters industry capital overhang by deploying proprietary AI tools and maintaining a selective investment strategy that has historically generated trillions in public market value through companies like Apple and Nvidia. While navigating geopolitical shifts by separating its Chinese operations and adapting to a regulatory landscape that has drastically reduced startup formation there, Sequoia continues to back founders with exceptional curiosity despite unconventional profiles.
- All-In Podcast28 min
YouTube CEO Neal Mohan on AI, Censorship & the Future of Creators
Neal Mohan, Chamath, Jason, Friedberg, Ari
YouTube CEO Neal Mohan outlined the platform's dominance with 2 billion monthly active users and over $70 billion paid to creators, while addressing tensions between its 55/45 revenue model and high-profile creators who opt for direct monetization. Mohan defended YouTube's algorithmic fragmentation as a driver of niche engagement while highlighting new AI initiatives that prioritize creator likeness rights and transparency labels over blanket bans. The discussion further detailed strategies to balance global moderation complexities with evolving regulations and a renewed focus on YouTube Premium and TV to reinvent the viewer experience.
- All-In Podcast27 min
Alibaba's Joe Tsai on US-China Rivalry, AI Future, Owning the Nets/Liberty, Caitlin Clark's Impact
Joe Tsai, Caitlin Clark, Chamath, Jason, Friedberg
Business leader Joe Satt outlines Alibaba's strategic pivot toward AI-driven efficiency, highlighting a 14.5% stock surge following the Qwen 2.5 Max launch and a corporate culture where 30% of engineering code is now AI-generated. He contrasts U.S. and Chinese market dynamics by discussing the WNBA's surge in popularity driven by Caitlin Clark while arguing that U.S.-China relations represent necessary economic competition rather than bitter rivalry, noting China's 50% corporate AI adoption rate. Satt further critiques structural differences in American versus Chinese education and governance, asserting that the future of technological progress relies on cooperation in fields like medicine rather than a zero-sum race for dominance.
- All-In Podcast12 min
The Next Bubble Is Already Here - Chamath Palihapitiya
Chamath Palihapitiya, Jason, Friedberg, Nick
Speakers warn that the private equity sector, having grown to $5 trillion through artificial borrowing, faces a structural collapse driven by mismanagement and stagnant distributions as capital migrates toward a new bubble in private credit. To address the dysfunction of traditional IPOs and flawed SPAC structures, the Raptor 2 initiative has secured backing from 98.7% of blue-chip institutional investors to introduce a transparent, performance-aligned model for high-growth companies. Future iterations, Raptor 3, propose a "pre-baked IPO" using pure common stock to eliminate conversion risk and ensure fair pricing for public shareholders.
- All-In Podcast54 min
Ro Khanna Calls Out Both Parties: Immigration, Tech & Free Speech
U.S. Representative Rohit "Roe" Khanna detailed his vision for immigration reform, border security, and economic patriotism during a fifth podcast appearance, advocating for skilled talent pathways while rejecting blanket visa fees and the zeroing out of asylum claims. The Representative criticized the Democratic Party for alienating the tech industry and emphasized the need for a forward-looking agenda focused on domestic revitalization, AI innovation, and bipartisan crime solutions rather than constant opposition to the Trump administration. Khanna also addressed immediate legislative crises, including the government shutdown caused by constitutional disputes over funding freezes, while reaffirming his commitment to banning congressional stock trading and warning against political violence fueled by an attention-driven media ecosystem.
- All-In Podcast23 min
Rick Caruso on California’s Collapse: Broken Leadership, LA Wildfire Failures & the Fix
Rick Caruso, Karen Bass, Chamath, Jason
In the wake of the Palisades fires, developer Rick Caruso contrasts his private sector emergency preparations against the city's failures, blaming incompetent governance under Mayor Karen Bass for the destruction of 90% of the homes. Caruso argues that ideological politics have paralyzed local authorities, leading him to propose a competency-based administration that enforces zero tolerance for street encampments while simultaneously securing federal aid and infrastructure upgrades for rebuilding. As he evaluates potential political bids, Caruso emphasizes that California must prioritize practical solutions over political maneuvering to reverse systemic decay and restore the state's status as a national leader.
- All-In Podcast25 min
Arm CEO Rene Haas on AI: Nvidia Lessons, Intel’s Decline and the US-China Chip War
Rene Haas, Jensen Huang, David, Jason
Following a landmark September IPO that vaulted its valuation to $150 billion, Arm is leveraging its foundational IP to transition from a smartphone architecture provider into a strategic partner for Nvidia and a supplier for the emerging "Physical AI" robotics market. Chief Executive Officer Rene Haas is aggressively reshaping the company's global culture and engineering focus to accelerate speed-to-market, while explicitly navigating complex geopolitical frictions and supply chain constraints to maintain a unified global ecosystem. With its architecture underpinning critical advances in both data center training chips and energy-efficient endpoint inference, Arm is positioning itself to dominate a diverging semiconductor landscape where specialized hardware will define future AI capabilities.
- All-In Podcast1h 8m
Science Corner Special! David Friedberg, Cleo Abram, Alex Filippenko, and Keller Rinaudo Cliffton
David Friedberg, Cleo Abram, Alex Filippenko, Keller Rinaudo Cliffton
Vox alumna Cleo Abram, astrophysicist Alex Filippenko, and Zipline CEO Keller Renato Clifton converge to discuss the transformative potential of optimistic technology, from Abram's independent media platform that champions solutions over fear-mongering to Filippenko's insights on the James Webb Space Telescope's discovery of early galaxy formation and the critical funding crisis threatening scientific research. Clifton details Zipline's success in delivering over 115 million autonomous miles to save lives in developing nations and its rapid scaling in the U.S., arguing that reliable robotics are essential for future logistics and geopolitical stability. Together, these leaders emphasize that sustained investment in independent innovation and basic science is vital for creating better futures and expanding access to life-saving infrastructure globally.
- All-In Podcast31 min
Inside the GLP-1 Gold Rush: Eli Lilly CEO on New Breakthroughs, Addiction & Mental Health, Pricing
Dave Ricks, Chamath, Jason, Friedberg
Eli Lilly CEO David Ricks has steered the company to an 860% market capitalization increase and record-breaking Mounjaro sales by leveraging a massive research workforce and aggressive manufacturing expansion to secure global dominance in GLP-1 therapies. While the firm faces capital shortages in the broader biotech sector, it is diversifying its pipeline beyond weight loss to address brain disorders and developing oral formulations to improve accessibility without compromising the high R&D reinvestment model Ricks defends. Personalized by Ricks' own successful treatment, the company balances aggressive clinical innovation with strategic supply chain controls to maintain its competitive edge against emerging international rivals.
- All-In Podcast29 min
Eric Schmidt on AI, the Battle with China, and the Future of America
Eric Schmidt, Chamath, Jason, Friedberg
Former Google CEO Eric Schmidt outlines a strategic framework where the immediate AI revolution remains underhyped and distinct from the imminent arrival of autonomous agents, while warning that Western nations must counter China's aggressive pivot toward open-weight models and advanced robotics. Schmidt anticipates a future military doctrine defined by millions of AI-driven drones that create high-deterrence stalemates rather than traditional combat, driven by the obsolescence of fixed military infrastructure. Simultaneously, he emphasizes that US geopolitical resilience depends on leveraging domestic capital markets and releasing smaller open-source models to maintain control over handheld device proliferation amidst global demographic declines.
- All-In Podcast1h 22m
Charlie Kirk Murder, Assassination Culture in America, Jimmy Kimmel Suspended, Ellison Media Empire
Charlie Kirk, Jimmy Kimmel, Ellison, Chamath, Jason, Friedberg, Zach, Sax
Following the murder of conservative activist Charlie Kirk by Tyler Robinson, a discussion emerges attributing the violence to a radicalized generation shaped by algorithmic extremism and social isolation rather than a random act. The event has triggered a broader national debate regarding the rising acceptance of political violence and the specific cancellation of Jimmy Kimmel, which hosts frame as a symptom of media consolidation and the erosion of free speech norms. Participants conclude by calling for a societal pledge against political violence while analyzing how tech giants and media moguls are reshaping the information landscape that fuels such ideological fractures.
- All-In Podcast25 min
Solana’s Anatoly Yakovenko on Crypto's Next Era: Quantum, AI, and the Future of Money
Anatoly Yakovenko, Chamath, Jason, Friedberg
Solana co-founder Anatoly Yakovenko outlines a transformative financial vision where $1.7 billion institutional tokenization and new regulatory frameworks like the "Genius Act" unlock trillions in stablecoins and real-world assets on Solana as the global execution layer. He predicts that within five years, the internet will surpass China and Japan as the top holder of US treasuries, driven by quantum-resistant cryptography and a synchronized, speed-of-light settlement network. This shift aims to displace traditional banking margins and integrate regulated entities like NASDAQ, provided that legal clarity enables the mass adoption of tokenized securities and uncapped economic utility.
- All-In Podcast26 min
Uber CEO Dara Khosrowshahi on self-driving's future, changing business model, job displacement
Dara Khosrowshahi, Elon, Chamath, Jason, Friedberg
Uber CEO Dara Khosrowshahi outlines a strategy to remove safety drivers from its fleet by the end of the current year while maintaining a hybrid human-AV model to maximize asset utilization across partners like Waymo and Chinese robotics firms. Concurrently, the company plans to deploy its substantial free cash flow into a $20 billion stock buyback and direct AV investments, positioning its network as an essential demand layer for future fleet operators. This approach aims to expand autonomous adoption to 20% of global rides within a decade, creating a transition period where drivers are retained through platform growth and pivoted into new roles like AI data labeling.