Leo Marani

Gene genies: CRISPR’s critical moment

Jason Palmer, Rosie Bloor, Emily Steinmark, Leo Marani, Eleanor Whitehead

The 2020 Nobel Prize in Chemistry recognized Emmanuelle Charpentier and Jennifer Doudna for CRISPR, a precision gene-editing tool now enabling curative treatments like Kisjevi for sickle cell disease while facing regulatory hurdles distinct from traditional genetic modification. Simultaneously, Asian markets drove nearly two-thirds of global gold demand to hedge against currency instability and capital controls, with India and China leading consumption despite the trade deficits this high import volume creates. In New Zealand, an accelerated net brain drain of nearly 129,000 emigrants was fueled by economic recession and housing costs, as professionals migrated to Australia seeking higher wages under the Trans-Tasman Agreement.