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Steve Hsu

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  1. Dwarkesh Patel2h 21m

    Steve Hsu - Intelligence, Embryo Selection, & The Future of Humanity

    Steve Hsu, Richard Feynman, Gwern, Bezos

    Genomic Prediction leverages machine learning and a dataset of over half a million genomes to calculate polygenic risk scores for IVF embryos, enabling clinics to select children with improved health spans and reduced disease risk. The company's technology relies on an additive genetic architecture that allows for the optimization of complex traits without inherent trade-offs, while currently addressing limitations in cross-population accuracy by developing algorithms to identify causal variants across diverse ancestries. As the industry shifts from wet lab services to cloud-based analysis, these advancements position the firm to influence future applications in cognitive trait prediction and matchmaking, though they face ongoing challenges regarding regulatory hurdles and ethical debates over non-medical genetic selection.

Steve Hsu: Interviews, Talks and Panel Discussions