Surya Ganguli

AI at the Intersection of Bio | Vijay Pande, Surya Ganguli & Bowen Liu

Vijay Pande, Surya Ganguli, Bowen Liu

This event details the transformative shift in drug design from theoretical potential to operational reality, leveraging deep learning and massive protein sequence datasets to navigate the vast chemical space while addressing historical validation bottlenecks. By integrating single-cell foundation models and latent space theories, the discussion outlines strategies to overcome distributional generalization failures and reduce the 90% clinical trial failure rate through personalized medicine and optimized patient selection. Ultimately, the presentation projects a decade-long roadmap toward "digital human" simulation systems that aim to slash development costs and expand FDA-approved target coverage despite significant regulatory and interpretability hurdles.