New patent granted for: Selective Inhibitors of Alpha2-Containing Isoforms of Na,k-Atpase and Use Thereof for Reduction of Intraocular Pressure

Provided herein are alpha2-selective Na,K-ATPase inhibitors and prodrugs thereof, characterized by having a cyclic moiety attached to a digoxin or digitoxin derivative, as well as uses thereof in lowering intraocular pressure and in treating glaucoma and heart conditions.