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Milken Institute

Showing 136–150 of 2093 transcripts.

  1. 6 min

    LeadersLink Kapila Viges

    Kapila Viges

    Kapila Vygis, CEO of the MPN Research Foundation, leveraged the LeadersLink program to secure mentorship and partnerships necessary for establishing a large-scale real-world evidence registry for myeloproliferative neoplasms. This initiative aims to collect electronic medical records to identify disease progression biomarkers and validate "progression-free survival" as a clinical trial endpoint for the 300,000 U.S. patients affected by these rare blood cancers. By adopting a phased roadmap developed with IQVIA and input from diverse stakeholders, the foundation is addressing data quality and cost sustainability to ultimately create curative-focused treatment strategies.

  2. 6 min

    LeadersLink Eszter Hars

    Eszter Hars, Esther Harst

    Esther Harst, a molecular biologist and CEO of the Schwarzman-Diamond Syndrome Alliance, is deploying a patient-entered data platform to address the critical lack of "patient voice" insights in treating this rare genetic disorder that causes fatal leukemia in many patients. The initiative has secured IRB approval and is preparing to launch a pilot study to mobilize the community, facilitate clinical trial matchmaking, and catalyze global collaborations through an open architecture. Building on over 20 years of biotech experience, Harst aims to expand the program to the entire SDS community early next year after validating data utility and patient trust during the pilot phase.

  3. 21 min

    Conversation with UAE's Minister of State for AI & Digital Economy | Middle East & Africa Summit

    Omar Sultan Al Olama, Dan Murphy

    The UAE leverages an eight-year strategy and over 500 billion dirhams in investment to rank as a global leader in AI talent retention and deployment, recently securing U.S. authorization to export advanced NVIDIA chips for its massive "Stargate" infrastructure project. This initiative aims to eventually build a 5-gigawatt facility capable of producing 60 trillion AI tokens annually, distinguishing the nation's long-term approach from short-term market hype while explicitly prioritizing ethical frameworks to mitigate job displacement through targeted reskilling and retirement programs.

  4. 1h 2m

    Global Overview: Innovation, Partnerships, and Growth | Middle East & Africa Summit 2025

    Hadley Gamble, His Excellency Jasem Al Budaiwi, Her Excellency Mariam bint Mohammed AlMheiri, Yasseen Mansour, Michael Milken, Yassine Mansour, Jasem Al Budaiwi, Mariam bint Mohammed AlMheiri

    The 46th GCC Summit united regional leaders to prioritize collective defense following recent security threats while accelerating economic diversification, evidenced by non-oil GDP reaching 76% and the UAE becoming the global top destination for millionaires. Strategic investments totaling $150 billion target Africa's demographic growth and energy sectors, complemented by a joint AI strategy designed to transform government services and healthcare across the region. Positioned as a neutral mediator in global affairs, the bloc combines regulatory stability with massive infrastructure projects to attract capital flows and challenge traditional economic centers like Europe and the United States.

  5. 42 min

    Vision, Velocity, Victory: The Sports Investment Playbook | Middle East & Africa Summit 2025

    Dhani Jones, Ben Harburg, Jamie Salter, Danny Townsend, Susie Wolff

    Over $60 billion in capital from Middle Eastern sovereign wealth funds is reshaping the global sports landscape by transforming the region into a neutral hub for investment comparable to Silicon Valley. This influx drives a strategic shift from traditional linear broadcasting to digital direct-to-consumer models while supporting economic diversification under Crown Prince vision, alongside landmark investments in the PFL, PGA Tour, and Saudi Pro League. Concurrently, the sector is leveraging high-quality content like "Drive to Survive" to fuel a projected $1 trillion women's sports market by 2030 and identifying Africa and India as the next major growth engines for talent and commerce.

  6. 29 min

    The Story Economy: Hits, Talents, & the Forces that Shape Culture | Middle East & Africa Summit 2025

    Camila Cabello, Jane Millichip, Louise Tabbiner

    Camila Cabello and Jane Tranter discussed the evolving landscape of global storytelling, highlighting how diverse narratives from films like *Roma* and *Sing Sing* can drive tangible social change through the emerging role of the "Impact Producer." The dialogue examined industry trends where Gen Z demonstrates sustained attention for quality content while AI and deepfakes necessitate stricter media literacy and ethical copyright protections. Ultimately, the speakers urged investors and creators to prioritize authentic, human-led storytelling that maximizes cultural bridges and secures measurable real-world outcomes in a sector valued at £125 billion.

  7. 1h 23m

    Leading the Next Era of Health | Future of Health Summit 2025

    Bertha Coombs, Joe Daly, Jeremy David, Shane Jacobson, Sarah London, Baligh Yehia, Esther Krofa

    Hosted by the Milken Institute in Washington, the 2025 Future of Health Summit convened over 200 speakers to address urgent systemic challenges including rising costs, stagnant life expectancy, and a 10-point decline in public trust. The event highlighted critical interventions such as Dr. Jill Biden's new Women's Health Network, Centene's food-as-medicine data initiatives, and Jefferson Health's AI-driven physician support programs, while launching nine strategic publications on biomedical research. Key participants navigated complex tensions regarding AI's role in workflows, the need for new financing models for expensive therapies, and the precarious status of Affordable Care Act tax credits, ultimately urging leaders to leverage micro-level patient-clinician trust for future reform.

  8. 21 min

    US Department of Health & Human Services Deputy Secretary Jim O'Neill | Future of Health Summit 2025

    Jim O'Neill, Esther Krofah

    The "Make America Healthy Again" agenda reorients the HHS from reactive sick care to preventive health by restoring the CDC's 1946 mission, recruiting AI and scientific specialists, and prioritizing radical transparency to rebuild public trust. This strategy integrates internal AI deployment and voluntary drug price negotiations to accelerate innovation while shifting federal cooperation with states toward data-driven surveillance and SNAP-funded nutrition improvements. Although government shutdowns have impacted staff morale, the administration targets a revitalized healthcare infrastructure through updated dietary guidelines and sustainable partnerships with industry and academia to combat chronic disease and pandemic risks.

  9. 56 min

    Innovating Hope: Charting the New Era of Alzheimer's & Other Dementias | Future of Health Summit

    Allison Aubrey, Kris Engskov, Jessie Fahrbach, Howard Fillit, Richard Isaacson, Joanne Pike, Chris Inskov

    Recent FDA approvals of amyloid-targeting drugs and advanced biomarkers have established the foundation for a new era of disease-modifying treatments, prompting a strategic industry shift toward preclinical intervention and combination therapies targeting multiple pathological pathways. Concurrently, integrated care models like the GUIDE initiative are reducing hospitalizations while AI-driven diagnostics and lifestyle-based prevention strategies aim to address the critical shortage of providers for the estimated 47 million Americans with silent Alzheimer's pathology. With significant government funding increases and projected 2030 innovations in low-cost at-home monitoring, the field is rapidly evolving toward a precision prevention framework that combines pharmacological, metabolic, and digital interventions to delay cognitive decline.

  10. 35 min

    What Does Smart Implementation of AI in Health Look Like? | Future of Health Summit 2025

    Michael Milken, Amy Gleason, Eric Lefkofsky

    The Center for Medicare and Medicaid Services is accelerating a $2 trillion annual overhaul by deploying AI-driven interoperability frameworks and consolidating fragmented data to eliminate systemic waste projected to exceed $10 trillion by 2034. Personal case studies illustrating severe diagnostic delays have catalyzed recruitment of top tech talent to build a unified provider directory and a personal AI health companion designed to guide patients through complex care journeys. By setting government infrastructure guardrails while allowing private sector innovation, this strategic vision aims to transform healthcare from a resource-draining liability into a predictive, efficient ecosystem capable of preventing costly medical events.

  11. 31 min

    Forging Asset Owner Alliances for Capital Deployment: Brazil & Beyond | Global Investors' Symposium

    Dan Carol, Régine Clément, Amy Hepburn, Anna Murray, Kirsten Simpson

    Major institutional investors, including the Ontario Teachers' Plan and the Australian Future Fund, are advancing climate strategies by integrating systemic risk analysis and direct engagement into fiduciary duties despite contrary media narratives. This shift is characterized by a pivot from simple net-zero declarations to active decarbonization tactics, such as acquiring fossil assets to transition them and investing in supply chains rather than solely targeting "green" sectors. As these entities collaborate through networks like the Investor Leadership Network, they are establishing new frameworks for blended finance and preparing high-stakes engagements for upcoming COP processes to drive tangible capital deployment.

  12. 38 min

    Building the Future: Strategic Leadership in Critical Minerals | Global Investors' Symposium SP

    Kanika Singh, Luciana Costa, Marcelo Paiva, André Simão, Thiago Toscano

    Panelists from Itamina, Sigma Lithium, and Brasilian Nickel detailed a strategic pivot where environmental compliance, innovative processing technologies like heap leaching, and zero-waste operations are leveraged to secure competitive advantages in the global critical minerals market. This sustainable model attracts sovereign funds and Western governments seeking to diversify supply chains away from Asian dominance, supported by new Brazilian financing initiatives such as BNDES's 1 billion BRL Critical Minerals Fund. Consequently, industry leaders project that Brazil is poised to transform from a raw material exporter into a trusted, low-carbon supplier of battery materials by integrating domestic value chains and utilizing transparency to reduce capital costs.

  13. 16 min

    Conversation with H.E. Majid Al Suwaidi, CEO of ALTÉRRA | Global Investors' Symposium São Paulo

    Majid Al Suwaidi, Fabio Turci

    Founded at COP28 by former Director-General Majid Al Suedi and major financial partners Brookfield, TPG, and BlackRock, Altera is a $30 billion climate investment vehicle designed to mobilize an additional $250 billion from the private sector over the next three to five years. The fund operates a dual mandate splitting capital between a global Transformation Fund and a dedicated Global South Fund, with a strategic focus on clean energy including nuclear power, industrial decarbonization, and emerging climate technologies. As of now, the entity has deployed capacity equivalent to 90 gigawatts across five continents while generating commercial returns that exceed sector expectations, validating its model to attract further institutional co-investment ahead of COP30.

  14. 41 min

    Global Markets: Partnerships for Sustainability & Prosperity | Global Investors' Symposium São Paulo

    Rodrigo Bettini, Roberto Campos Neto, Isabelle Millat, Melanie Nakagawa

    Former Brazil Central Bank President Roberto Campos Neto highlighted how digital financial tools like PIX and Open Finance expanded inclusion to over 90% of the population and lowered interest rates by 2.9%. Microsoft's Melanie Nakagawa and Barclays' Isabel Mila detailed parallel efforts to scale sustainability, with Microsoft committing $1 billion to climate innovation and Barclays aiming for $1 trillion in sustainable financing by 2030. Collectively, these leaders framed Brazil's upcoming COP30 as a pivotal moment where digital infrastructure and nature-based solutions must converge to drive regional economic prosperity.

  15. 48 min

    The AI Surge: Powering Innovation & Global Competitiveness | Global Investors' Symposium São Paulo

    Ana Clara Martins, Carlos Costa, Tallis Gomes, Maren Lau, Mateus Costa Ribeiro

    Panelists from Valor, Meta, G4 Educação, and Enter discussed the rapid maturation of AI adoption in Latin America, highlighting how Brazilian firms are leveraging generative intelligence to drive double-digit margin improvements and democratize competitive advantages for small and mid-sized businesses. The dialogue emphasized that while execution bottlenecks and organizational complexity currently hinder enterprise integration, Brazil's strategic assets—including clean energy, rare earth reserves, and a robust digital payments ecosystem—position the region as a global export hub for AI-native financial and legal services. Ultimately, the group called for pro-innovation regulations to replace restrictive frameworks, arguing that fostering talent acquisition and infrastructure investment is essential to unlocking trillions in potential value through agent-driven economic transformation.