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Conference Presentation, Keynote

Reshma Shetty Speaks at Y Combinator's Female Founders Conference 2016

  • Core Mission & Vision: Ginkgo Bioworks aims to "make biology easier to engineer" by designing microbes and organisms to spec, treating biology as the most powerful manufacturing platform capable of self-replication, self-repair, and nanometer-precision assembly.
  • Founding Context: The company was founded in 2008 in Boston by Reshma Saujani (CEO) and co-founders Tom Knight, Barry Smith, Jason Kelly, and Austin, originating from an MIT graduate student environment where engineering and computer science perspectives were applied to biological systems.
  • Early Strategy & Bootstrapping: Operating virtually for the first year during the 2008 financial crisis, the team secured equipment for approximately $150,000 by dumpster diving at closing biotech firms, rejecting conventional wisdom that a lab requires millions in startup costs.
  • Product-Market Fit Timeline: The company spent five years iterating on hypotheses and securing government grants before identifying a viable business model; they signed their first customer in 2012 and secured multiple customers by 2013.
  • Business Model: Ginkgo identified a $3.5 billion market for "cultured ingredients" (e.g., rose fragrance, vitamins, flavors), replacing plant-based extraction with five-day yeast fermentation processes to eliminate multi-year growing cycles.
  • Funding Milestones: Ginkgo deliberately delayed venture funding until achieving clear product-market fit and traction; they joined Y Combinator in 2014, raising a $9 million Series A and a subsequent $45 million Series B.
  • Diversity Statistics & Trends: Prior to 2015, female representation stood at roughly 27%; after doubling headcount post-Series B, the percentage of women in new job offers paradoxically decreased, highlighting a critical hiring gap.
  • Diversity Strategy: Co-founder Reshma Saujani is adopting a "Moneyball" approach to diversity, viewing underrepresented women and minorities as "undervalued assets" in the marketplace to gain a competitive edge in hiring.
  • Forward-Looking Statements: The company aims to become the "Intel of biology," with a strategic focus on reconciling the immediate need for business sustainability with long-term goals of building a diverse workforce before scaling further.
  • Leadership Philosophy: Saujani emphasizes that starting a company is justified only by a passionate mission to solve a specific problem, serving as the necessary compass to endure the hardships of the startup lifecycle.