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  1. Milken Institute37 min

    MIc'd Up | Part 2: A Conversation with Ernest Moniz

    Ernest Moniz, Alan Schwartz, Alan M., David Sanger, Alan Magnuson

    Former Energy Secretary Ernest Moniz outlines the strategic logic behind the 2015 Iran Nuclear Deal, emphasizing its unprecedented verification mechanisms and the administration's successful monofocus on nuclear containment despite broader regional tensions. Simultaneously, he details the Nuclear Threat Initiative's urgent efforts to secure high-enriched uranium and research reactors across the former Soviet bloc and Africa to prevent terrorist acquisition. These security measures are paired with a proposal to leverage the global energy transition, utilizing carbon capture and advanced storage technologies to create economic opportunities while reducing reliance on fossil fuels.

  2. Milken Institute26 min

    MIc'd Up | Part 1: A Conversation with John S. Watson

    John S. Watson, Brian Sullivan

    Chevron CEO John Watson warns that California's aggressive regulatory framework has driven up energy costs, decimated manufacturing, and eroded the middle class, urging a return to free-market mechanisms to stabilize the industry. Despite these domestic headwinds, Watson outlines Chevron's aggressive global expansion strategy, which includes quadrupling Permian Basin output through capital generated by massive LNG investments in Australia and a joint venture with Exxon in Kazakhstan. While noting that OPEC's influence has waned in favor of shale producers and resilient Russian exports, the executive emphasizes that technological advancements are offsetting high exploration risks and driving wage growth in key U.S. energy hubs.

  3. Milken Institute21 min

    Lunch Program | Part 1: A Conversation with Wilbur L. Ross, Jr., Secretary, U.S. Dept. of Commerce

    Wilbur L. Ross, Jr., Gregory

    Commerce Secretary Wilbur Ross, who originally opposed Donald Trump during the Taj Mahal bankruptcy proceedings before offering his support, now leads the Department of Commerce with a mandate to prioritize bilateral trade agreements over multilateral ones. Under Ross's direction, the administration secured a 100-day window with China for specific deliverables while imposing tariffs on Canadian lumber, positioning these actions alongside expectations for 2% to 2.5% GDP growth once tax reforms and regulatory rollbacks are enacted. Despite facing a fragmented Republican Party and united Democratic opposition that slow legislative progress, Ross maintains that high-quality personnel and strong market sentiment will drive the administration's economic agenda.

  4. Milken Institute31 min

    MIc'd Up | Part 2: A Conversation with Elizabeth Blackburn

    Elizabeth Blackburn, Joon Yun

    Salk Institute President Dr. Elizabeth Blackburn discusses the biological mechanisms of aging and telomere maintenance with host Jun Yun, framing the extended human lifespan as an opportunity to maximize health span rather than a inevitable decline. The dialogue details how specific lifestyle interventions—including brisk daily exercise, seven hours of sleep, and cognitive reframing of stress—directly influence telomere length to mitigate risks of chronic diseases like Alzheimer's and diabetes. By integrating molecular biology with health psychology, Blackburn argues that dynamic gene expression allows individuals to actively shape their cellular health and extend their years of vitality.

  5. Milken Institute31 min

    MIc'd Up | Part 1: Jeb Bush in Conversation with Terry Duffy

    Jeb Bush, Terry Duffy

    Jeb Bush and Derek Jeter announced their joint acquisition of the Miami Marlins, a venture designed to leverage data analytics and market growth while avoiding the financial pitfalls of high-salary player acquisition. The former Florida governor simultaneously urged for comprehensive federal reforms to resolve bureaucratic gridlock, advocating for tax code simplification, term limits, and a shift toward an economy-driven immigration system. While expressing cautious support for the current administration's foreign policy coherence, Bush emphasized the urgent need to address workforce displacement caused by automation through 21st-century educational overhauls.

  6. Milken Institute30 min

    MIc'd Up | Part 2: Pedro Domingos in Conversation with Eric Schmidt

    Pedro Domingos, Eric Schmidt

    Led by industry leaders like Bill Gates and Pedro Domingos, the event examines how converging advances in algorithms, data, and computing are shifting machine learning from rule-based programming to generalized intelligence. The presentation details critical hurdles in generalization and the urgent global talent shortage, while outlining transformative economic shifts where traditional hardware models face commoditization and new crowdsourced learning ecosystems emerge. Looking five to ten years ahead, the discussion predicts a workforce evolution where humans act as strategic captains alongside AI systems, enabling universal programming capabilities that could unlock a $5 trillion new world economy.

  7. Milken Institute29 min

    MIc'd Up | Part 1: A Conversation with John Chambers and Ken Griffin

    John Chambers, Ken Griffin, Gillian Tett

    Ken Griffin and John Chambers evaluate the early regulatory shifts of the new administration while advocating for a three-to-five-year strategic horizon to assess tax reform, healthcare restructuring, and a "fair trade" agenda. The leaders emphasize that prioritizing digital infrastructure, retaining high-skilled immigrant talent, and reforming K-12 education are critical for sparking innovation and overcoming stagnation in the U.S. IPO market. Despite these opportunities, both figures warn that a lack of a unified national strategy, combined with limited fiscal tools and potential geopolitical trade conflicts, could derail the economy's path toward sustained 4% growth.

  8. Milken Institute28 min

    MIc'd Up | Part 1: A Conversation with Angela Ahrendts

    Angela Ahrendts, Lucy Parker

    Angela Ahrens is redefining Apple Retail as a global community hub by transforming physical locations into "hardware" designed for social connection rather than mere sales transactions. This strategic shift introduces the "Today at Apple" curriculum and "Creative Pros" roles across 500 stores to teach public classes in coding and arts, aiming to combat social isolation while leveraging the fact that half of recent Genius Bar visits were for education. By prioritizing human connection and meaningful work, the initiative has driven employee retention to 82% and positions the company to set new standards for corporate social responsibility through free lifelong learning opportunities.

  9. Y Combinator34 min

    How Should Business Schools Prepare Students for Startups? – Jeff Bussgang and Michael Seibel

    Jeff Bussgang, Michael Seibel, Craig Cannon

    YC CEO Michael Seibel and HBS lecturer Jeff Busgang debate the persistent gaps between MBA education and startup execution, identifying technical deficits, lack of commitment, and excessive research as primary reasons for high rejection rates. While Business Schools like Harvard are adapting through physical integration with engineering departments and new joint degrees, the traditional curriculum often fails to instill the immediate traction and hands-on coding skills required by venture capitalists. Ultimately, Seibel advises non-technical founders outside top hubs to prioritize working at early-stage startups over pursuing an MBA, citing real-world experience as superior preparation for building transformational ventures.

  10. Y Combinator40 min

    At the Intersection of AI, Governments, and Google - Tim Hwang

    Tim Hwang, Craig Cannon

    Tim Wong, Google's Global Public Policy Lead for AI and Machine Learning, navigates the intersection of technical security challenges, privacy constraints, and societal impacts like job displacement. He highlights critical tensions between de-biasing data and protecting minority privacy while emphasizing that current adversarial vulnerabilities limit high-stakes automation adoption. To address these issues, Google promotes global policy experimentation and educational reforms that shift computer science toward example-based learning and domain-specific expertise.

  11. Y Combinator31 min

    Scaling Product | Fireside with Joe Gebbia and Reid Hoffman

    Joe Gebbia, Reid Hoffman

    Airbnb achieved product-market fit by abandoning scalable code solutions in favor of manual, non-scalable actions, such as founders personally photographing listings to overcome trust barriers and reduce user friction. To sustain hyper-growth while maintaining culture and empathy, the company institutionalized practices like hiring for future needs, training core values interviewers, and mandating that employees regularly experience the platform as travelers and hosts. This strategic focus on deep user connection and operational realism eventually enabled the expansion from a simple room-rental service to a comprehensive travel ecosystem featuring Experiences and a global network of professional photographers.

  12. Y Combinator33 min

    The Technical Advisor for Silicon Valley on HBO: Ed McManus

    Ed McManus, Craig Cannon

    Former Yardsale founder Ed McManus served as a technical advisor for *Silicon Valley* Season 3, where he guided writers to ensure code accuracy and advocated for realistic infrastructure choices like AWS adoption. His consultancy enabled the production to craft a plausible "Middle Out" algorithm and navigate the "Anti-Entourage" narrative constraint of engineered failures while integrating viral audience interactions through active fictional GitHub profiles. Ultimately, McManus departed after the season to return to entrepreneurship, citing the show's bleak conclusion as a resonant parallel to his own post-exit experiences.

  13. Y Combinator42 min

    Hiring Engineers with Ammon Bartram

    Ammon Bartram, Craig Cannon

    Amon Bartram, co-founder of the engineering recruitment startup TripleByte, details a methodology that replaces generic interview formats with four distinct, data-driven assessments designed to eliminate noise and accurately match specific company needs with candidate skills. By analyzing over 2,000 interviews, his approach identifies how traditional whiteboarding and credential-focused screenings often fail to predict job success compared to practical coding, debugging, and system design tasks. The presentation concludes with actionable recommendations for reducing interviewer bias, such as standardizing evaluation criteria and avoiding hazing, while advising candidates to focus on breadth-first search fundamentals and high-volume practice to improve their hiring outcomes.

  14. Goldman Sachs24 min

    Talks at GS – Dr. John J. DeGioia and Dr. Ruth Simmons: Confronting the Legacy of Slavery

    Dr. John J. DeGioia, Dr. Ruth Simmons, Jack DeGioia

    Georgetown University and Brown University have undertaken rigorous historical investigations that revealed their founding and financial stability were directly tied to the transatlantic slave trade and the sale of enslaved people. In response to these findings, Georgetown has initiated a renaming project to honor specific individuals from the 1838 sale, while Brown's leadership emphasizes that the legacy of slavery remains an active, unresolved force in contemporary society. Both institutions reject silence as a moral failure, positioning their transparency and ethical reckoning as essential models for addressing historical atrocities and their enduring social consequences.

  15. Y Combinator31 min

    Drew Houston : How to Build the Future

    Drew Houston, Sam Altman, Drew Haust

    Drew Houston co-founded Dropbox in 2007 after Y Combinator rejected his initial venture, forming a partnership with Arash Todd to build a file-syncing service that validated market demand through a viral referral program. The company evolved from a storage tool into a collaboration platform by strategically pruning unsuccessful products like Carousel and Mailbox to focus on its core value proposition. Houston subsequently shifted his leadership style from technical coding to strategic management, utilizing insights from literature and advisors to navigate scaling challenges while maintaining a private status to avoid public market volatility.