Latest Interviews
Showing 2341–2355 of 2,633 transcripts.
Clear all filters- Milken Institute34 min
A Conversation with Scott Gottlieb, Commissioner, U.S. Food and Drug Administration
Scott Gottlieb, Tanisha Carino, Michael Milken
The FDA is implementing a comprehensive strategic shift to accelerate drug approvals through digital health integration, organizational restructuring within the Office of New Drugs, and a transition to risk-based, post-market regulation for digital tools and manufacturing. This initiative aims to increase review productivity by 20%, publish hundreds of new guidances, and release detailed approval memos within 48 hours to enhance transparency while addressing pipeline disparities in rare versus common diseases. Concurrently, the agency prioritizes tobacco control through modified risk products and fosters market competition to lower drug costs, with Commissioner Gottlieb warning that ossified reimbursement models for novel therapies threaten future innovation if not adapted.
- Milken Institute36 min
Addressing Social Determinants to Improve Health Outcomes
Anand Parekh, Karen DeSalvo, Esther Dyson, Sergio Matos, Alan Moses, Lydia, Mark Hyman, Helen
Former health officials and community leaders convened to argue that social determinants like housing and food security drive 80% of health outcomes, citing Humana and CMS data where interventions yielded significant cost savings and improved well-being. Despite evidence supporting community health workers and local partnerships, the panel identified rigid funding structures, actuarial caution, and an overreliance on randomized trials as primary barriers to mainstreaming these models. Strategic recommendations include integrating social factors into Medicaid reimbursement, shifting from short-term grants to sustainable community ownership, and redefining health as a systemic design issue rather than a purely clinical one.
- Milken Institute24 min
A Conversation with Ben Carson, Secretary, U.S. Department of Housing and Urban Development
HUD Secretary Dr. Ben Carson applies a data-driven, surgical approach to dismantling bureaucratic hurdles and redefining the American Dream through integrated housing and workforce initiatives. Under his leadership, the agency has halved veteran homelessness via the HUD-VASH program and launched Envision Centers to consolidate resources for single parents, while prioritizing preventive health measures to mitigate lead exposure, mold-related asthma, and fall risks in aging communities. Looking toward 2025, the Secretary forecasts a strategic shift toward private-sector capital in Opportunity Zones and holistic community redevelopment models to ensure long-term fiscal sustainability amid a shifting demographic landscape.
- Goldman Sachs27 min
Dale Earnhardt Jr. - "Racing to the Finish"
Dale Earnhardt Jr., Dave D'Assi
After a nearly twenty-year NASCAR career, Dale Earnhardt Jr. retired and published his memoir *Racing to the Finish* to detail his trajectory from a modest weekly wage to a double Xfinity Series champion, highlighting the emotional weight of his 2004 Daytona 500 victory following his father's fatal crash. His career was ultimately defined by a series of undiagnosed concussions starting with a 2012 crash at Kansas, which led to cumulative brain injuries, a 2016 medical diagnosis by neurologist Mickey Collins, and a rigorous four-month rehabilitation protocol supported by his wife Amy. Earnhardt Jr. used his platform to advocate for updated concussion treatments that evolved from passive isolation to active brain rehabilitation, aiming to assist others in identifying symptoms and accessing modern care that was unavailable during the height of his suffering.
- Milken Institute27 min
CDC Director Robert Redfield: 'Opioid Epidemic is the public health crisis of our time'
This event details a strategic review of an organization facing significant funding uncertainties and access barriers while pivoting toward social justice, independent scientific research, and multi-year capital market transitions. Key figures addressed the contradiction between current resource limitations and plans to expand operations through federal partnerships over a projected three-year timeline to better manage global crises. Despite ambiguous historical anchors and disjointed narrative segments, the discussion concluded with a commitment to advancing systemic reforms and developing spiritual leadership capabilities among students.
- Lex Fridman42 min
Yoshua Bengio: Deep Learning | Lex Fridman Podcast #4
This event synthesizes current limitations in artificial neural networks, highlighting the need to shift from passive observation to active agent learning and the development of disentangled representations for better causal reasoning. It proposes that future progress depends on integrating unsupervised semantic understanding with supervised labels and leveraging machine teaching strategies to mimic human attention mechanisms. Furthermore, the discussion reframes AI safety priorities away from fictional existential threats toward immediate societal challenges like algorithmic bias, autonomous weapons, and the ethical alignment of systems through robust world models.
- The Economist28 min
Reverend Curry on Meghan, Harry and America
Curry, Meghan, Harry, Anne McElvoy
Presiding Bishop Michael Curry leveraged his historic role as the first African-American bishop of the Episcopal Church to deliver a sermon at the royal wedding of Prince Harry and Meghan Markle, framing romantic love as a spiritual discipline of sacrificial living that transcends cultural divides. He extends this theology to address contemporary social fractures, urging the church to model pluralism amid internal disagreements on LGBTQ+ inclusion while publicly challenging the Trump administration's immigration policies as theological heresies. Ultimately, Curry projects a global vision where the church actively pursues the abolition of poverty and war, asserting that Christian love must drive both personal reconciliation and political justice.
- Goldman Sachs34 min
Walter Isaacson: The Making of a Genius
Historian Walter Isaacson explores the intersection of creativity, entrepreneurship, and scientific curiosity, drawing parallels between New Orleans' modern diversity and historical innovation hubs while contrasting the foundational American influence of Benjamin Franklin with Leonardo da Vinci's interdisciplinary genius. Isaacson details da Vinci's meticulous anatomical research and engineering mindset, arguing that his scientific inquiries were essential to the realism in masterpieces like the *Mona Lisa* and *The Last Supper* rather than distractions from his art. Ultimately, the discussion advocates for a daily practice of "pure curiosity" to bridge the gap between statecraft and science, echoing the wisdom of Isaacson's uncle to prioritize storytelling over preaching in the pursuit of knowledge.
- Lex Fridman38 min
Steven Pinker: AI in the Age of Reason | Lex Fridman Podcast #3
Steven Pinker argues that human life is defined by the pursuit of fulfillment and well-being rather than mere survival or knowledge, positioning rationality as the key tool to achieve these goals. He challenges prevalent fears of artificial intelligence by asserting that current "existential risk" scenarios are incoherent, citing engineering safety cultures and the lack of inherent will to power in intelligent systems as evidence that AI will not enslave humanity. Instead of fixating on doomsday narratives driven by cognitive bias, Pinker advocates for leveraging AI to eliminate dangerous labor and redirect resources toward tangible threats like pandemics and climate change.
- Goldman Sachs21 min
Ellen Ochoa: Making History in Space
Former astronaut and NASA administrator Ellen Ochoa, the first Hispanic woman in space, reflects on her 28-year career spanning five missions that addressed ozone depletion and solar wind research while advocating for reframing engineering as a collaborative team sport. She details NASA's strategic pivot from internal manufacturing to commercial service partnerships with entities like SpaceX and the agency's continued reliance on 25-year international collaborations to sustain the International Space Station. Looking toward future exploration, Ochoa emphasizes the technical feasibility of lunar and Mars missions contingent on long-term political will and current ISS research, while underscoring leadership principles such as "seek first to understand" that guided post-Columbia safety protocols.
- Milken Institute38 min
The Stories We Tell Panel Discussion
Tracey Woon, Drue Kataoka, Frank Luntz, Jay Shetty, Drew
UBS-hosted panelists Frank Vassiliadis, Drew Shindler, and Jay explored the intersection of storytelling, technology, and mindfulness to address modern societal challenges ranging from cross-cultural values to the rise of "fake news." The speakers argued that true influence requires deep introspection and honest self-awareness, contrasting passive digital consumption with the critical engagement fostered by arts-integrated education and genuine social impact. Concluding with a guided meditation, the session emphasized that internal peace and parental modeling are essential foundations for navigating a media landscape increasingly dominated by superficial metrics.
- Goldman Sachs45 min
Stephen Pagliuca: Leadership in Business and Basketball
Steve Pelyuka leverages his background as a Duke basketball scholarship athlete turned accounting professional to co-found Bain Capital and drive its evolution from a mid-market buyout firm into a global leader emphasizing digital transformation and the "Double Impact Fund." As co-owner of the Boston Celtics since 2002, he orchestrated a championship turnaround by pioneering data analytics in player acquisition and establishing the Shamrock Foundation to generate over $1 million annually for local charities. Pelyuka also warns of impending fiscal crises driven by state-level healthcare costs while advocating for diversified investment strategies to navigate potential market instability.
- The Economist24 min
The data revolution: privacy, politics and predictive policing
Dr Tom Devlin, Trump, Nick Bowers, Carol Reed, Hal Hodson, David Carroll, Mark Zuckerberg, Jamie Garcia, Hamid Khan, Sergeant David Rich, Anthony, Leo Hu
The event examines how the exponential growth of data generation is transforming healthcare through AI tools like Viz.ai while simultaneously enabling invasive surveillance in consumer marketing, law enforcement, and state control systems. Key case studies include the medical success of stroke detection algorithms, the electoral manipulation via Cambridge Analytica's unauthorized data harvesting, and the controversial implementation of China's Social Credit System. Furthermore, the discussion highlights significant ethical conflicts surrounding predictive policing biases in Los Angeles and the ongoing legal battles to ensure transparency in how personal data is collected and utilized by governments and corporations.
- Goldman Sachs23 min
Muffet McGraw: Winning in Women’s Sports
Notre Dame head coach Muffet McGraw reflects on her eight Final Four appearances and two national championships while advocating for women in coaching and challenging media double standards. Drawing on her background as a seven-on-seven pioneer, she details a recruiting philosophy prioritizing character over talent and the strategic implementation of an all-female coaching staff to foster role modeling. Her insights further explore the resilience required to overcome severe team injuries and adversity, exemplified by the 2018 championship run, alongside her observations on the persistent scrutiny female leaders face regarding emotional expression and professional behavior.
- Y Combinator40 min
How to Apply and Succeed at Y Combinator by Dalton Caldwell
The event details how applying to Y Combinator serves as a critical strategic exercise that forces founders to clarify business fundamentals while systematically dismantling common misconceptions regarding timing, industry fit, and team requirements. It outlines a rigorous application protocol where completeness, concise storytelling, and demonstrable execution capability outweigh prior experience or networks, emphasizing that the process itself builds skills transferable to scaling the venture. Furthermore, the discussion highlights that the partnership interview functions as a collaborative verification of these metrics rather than a trivia quiz, providing specific feedback loops that encourage strategic re-application based on tangible progress.