Latest Interviews
Showing 271–285 of 1,099 interview transcripts.
Clear all filters- a16z40 min
Can AI Fix Housing and Healthcare Affordability?
Erik Torenberg, Alex Immerman, Minna Song, Tony Stoyanov
The firm has invested in Elyse AI, a 2017-founded startup led by Minna and Tony, to deploy autonomous building technology across the housing and healthcare sectors. This solution addresses a 5-million-unit US housing deficit and soaring administrative costs by doubling employee productivity, reducing lease cycles to under two weeks, and expanding into medical intake and patient engagement. By targeting a future where these two sectors consume only 20% of household income, the initiative aims to replace manual inefficiencies with AI-driven operations that unlock latent supply and lower long-term living expenses.
- Y Combinator36 min
Anthropic Co-founder: Building Claude Code, Lessons From GPT-3 & LLM System Design
Tom Brown, Melanie Warrick, Mark Mandelbaum, Mark Mirchandani, Brian Dorsey, Priyanka Vergadia, Priyan Kavanagh, Leslie Kendrick, Francesc Campoy
Vivek Mirchandani, a founding engineer at OpenAI and Anthropic, pioneered the scaling laws strategy that established the link between compute investment and model intelligence before co-founding Anthropic to prioritize AI safety and alignment. Under his leadership, Anthropic shifted focus from early consumer prototypes to building robust training infrastructure, ultimately delivering the coding-dominant Claude 3.5 Sonnet model while navigating global bottlenecks in electricity and multi-vendor hardware supply chains. The organization's approach combines internal qualitative benchmarking with a multi-vendor hardware strategy to drive the largest infrastructure buildout in history, positioning the company at the center of the coming wave of AGI development.
- Sequoia Capital30 min
Scaling the 'Cursor for Slides' to $50M ARR ft Gamma founder Jon Noronha
Founded in 2020 by John Nerona and Grant, Gamma is a visual storytelling platform that has grown to over 50 million users and $50 million in ARR by combining Notion-style writing with Canva-like design. The company survived an existential threat in 2023 by pivoting to a multi-model AI strategy that leverages handcrafted prompts across models like Claude and Gemini to optimize creative output and cost efficiency. With a lean team of 30, Gamma is now expanding its block-based editor into documents and websites while preparing to launch an API in September for automated workflow generation.
- a16z42 min
Google DeepMind Lead Researchers on Genie 3 & the Future of World-Building
Jack Parker-Holder, Shlomi Fruchter, Anjney Midha, Marco Mascorro, Justine Moore, Erik Torenberg
Google DeepMind has released Genie 3, a research preview that generates interactive, photorealistic 3D worlds in real-time from text prompts to support navigation and control. Built by integrating insights from three internal projects, the model introduces spatial memory for one-minute object persistence and emergent physical reasoning to distinguish it from previous video generation systems. While currently limited to visual simulation without audio, Genie 3 aims to bridge the sim-to-real gap for robotics and agent training by providing diverse, high-fidelity environments free from physical data collection risks.
- a16z42 min
The Current Reality of American AI Policy: From ‘Pause AI’ to ‘Build’
Martin Casado, Anjney Midha, Erik Torenberg
Driven by the rapid rise of open-source models from competitors like DeepSeek, US policy has pivoted from existential risk narratives to a 2024 Innovation Action Plan co-authored by technologists to prioritize scientific discovery over restrictive liability frameworks. This new strategy replaces theoretical safety concerns with an empirical evaluation ecosystem and predicts a market split where open weights serve sovereign entities while closed-source models power frontier applications. By rejecting historical precedents of technology lock-downs, the plan aims to maintain global leadership through open collaboration and rapid iteration despite acknowledging a lack of direct academic funding.
- Goldman Sachs28 min
Markets Brace for Rate Cuts
Economic analysts Josh Schifrin and Dominic Wilson project that the U.S. economy will endure tariff shocks through non-recessionary growth while anticipating a 25 basis point Federal Reserve rate cut in September driven by a weakening labor market. Their strategy favors a continued bullish stance on U.S. equities despite valuation froth, offset by risks in the dollar's structural downtrend and global allocation shifts toward Japan and away from Europe. The hosts emphasize that upcoming payroll reports and AI capital efficiency scrutiny will remain the primary catalysts for market direction and central bank policy pacing throughout the remainder of the year.
- a16z28 min
This Week in AI: GPT-5 Ships, 4o Pulled Back, Grok Imagine Goes Social
Olivia, Justine Moore, Jensen Huang, Anish
xAI integrated its Grok Imagine tool directly into the X platform to enable rapid, uncensored image and video creation, while OpenAI deprecated GPT-4o in favor of GPT-5 despite facing user backlash over its sterile tone and subsequent regulatory scrutiny in Illinois. Concurrently, Google introduced Genie 3 for generating interactive 3D worlds and 11 Labs launched a commercially licensed music model to solve copyright barriers, signaling a shift toward deeper native AI integration in social and creative ecosystems. These developments highlight a growing market divergence where rapid "vibe coding" prototypes for consumers struggle with security risks, prompting a strategic split between simplified user tools and complex enterprise environments.
- Goldman Sachs43 min
Searching for Signals: BlackRock’s Raffaele Savi on the Future of Systematic Investing
Raffaele Savi, Global Head of BlackRock Systematic, leads the firm's 40-year legacy quantitative team overseeing over $317 billion in assets while driving the strategic shift from traditional factor investing to AI-powered models that integrate big data and generative technologies. Addressing recent market volatility with a "dynamism over dogmatism" philosophy, Savi highlights how these advanced tools are expanding systematic capabilities into illiquid private markets and enhancing portfolio resilience against unpredictable shocks. This evolution reflects a decade of growth where hybrid teams blend financial and hard science expertise to navigate complex environments, prioritizing long-term risk management and client outcomes over short-term alpha chasing.
- Sequoia Capital39 min
How AI Digital Minds Can Scale Human Connection ft Delphi’s Dara Ladjevardian
Dara Ladjevardian, Sonya Huang, Jess Lee
Delphi is developing an adaptive platform that constructs personalized "digital minds" using temporal knowledge graphs to capture the specific reasoning, heuristics, and voice patterns of individual users. Following a strategic pivot from licensing public figures to empowering authentic self-created twins, the technology enables high-value applications in enterprise knowledge scaling, personalized education, and automated lead qualification while strictly adhering to identity verification and safety guardrails. Founder Dara predicts that by 2026, these digital representations will normalize as a consumer standard, transforming human energy and authentic connection into a premium economic resource as the market shifts from passive information feeds to active conversational media.
How The Rarest Company On Earth Raised $75M from Altimeter
John Maslin, Brad Gerstner, Erik Kriessmann, Rajeev Misra, Molly O'Shea
Vulcan Elements has secured a $65 million Series A round to accelerate its mission of decoupling U.S. rare earth magnet supply chains from China by developing sovereign refining and manufacturing capabilities. The company, led by CEO John Maslin and supported by an advisory board including former Deputy National Security Advisor Nadia Shadlow, is already operating at over 95% capacity while fulfilling Defense Department contracts for critical military and emerging physical AI technologies. With new funding, Vulcan plans to announce a second facility and triple its engineering workforce to meet a projected 10x surge in global demand by 2027 as mandated by recent federal legislation requiring verified domestic provenance for defense hardware.
- a16z43 min
GPT-5 and Agents Breakdown – w/ OpenAI Researchers Isa Fulford & Christina Kim
Isa Fulford, Christina Kim, Erik Torenberg, Sarah Wang
OpenAI leadership and key architects Christina and Issa unveil GPT-5 as a significantly more useful frontier model that prioritizes cross-domain utility, massive coding improvements, and reduced hallucinations over isolated benchmark scores. The update integrates advanced reasoning capabilities and autonomous agent functions to lower barriers for non-technical users while shifting evaluation metrics toward real-world usage data and specialized synthetic datasets. By optimizing pricing and balancing helpfulness against sycophancy, the release aims to establish a new baseline for general intelligence that transforms complex, multi-step workflows into accessible daily tools.
Carta CEO Henry Ward on Raising $1B, Path to ~$500M ARR, & the Move into PE
Carta, a platform currently approaching $500 million in annual recurring revenue, is scaling its software infrastructure from the venture capital sector into the vastly larger private equity and credit markets by displacing manual spreadsheet workflows. Under CEO Henry Ward's dual strategy of product innovation and internal AI transformation, the company focuses on "execution startups" that out-manage incumbents while utilizing algorithmic tools to enhance operational efficiency and debuggability. With a board comprising major investors like Andreessen Horowitz and Silver Lake, Carta aims to become the definitive institutional standard for fund accounting and capital management within the next five years.
- a16z45 min
From the Dot-Com Crash to the AI Era: How Builders Survive Waves of Disruption
Martin Casado, Raghu Raghuram, Jeetu Patel
The presentation analyzes how VMware was disrupted by cloud computing and containers before examining Cisco's strategic reset to regain innovation velocity by operating as a large startup while targeting tenfold performance gains. Leaders outline a specific execution framework that protects early-stage innovation teams through narrow ideal customer profiles and a product-led culture to navigate the shift from IT buyers to direct end-user adoption. Furthermore, the discussion positions Cisco as essential AI infrastructure, arguing that surging autonomous agent demand will require a 100x expansion in network capacity driven by a hybrid strategy of vertical integration and open ecosystem partnerships.
- a16z38 min
The Future of AI Video: How Fal.ai is Making AI Video Faster & Easier
Burkay Gur, Batuhan Taskaya, Jennifer Li
This event details the strategic evolution of a company that pivoted from cloud infrastructure to a multi-cloud generative media marketplace in response to the 2021 GPU crunch and stable diffusion surge. The organization addresses volatile video model dynamics by deploying a proprietary orchestration architecture that manages tens of thousands of GPUs, enabling sub-second inference for fine-tuning and complex chained workflows. Looking ahead, the discussion projects 2025 as a critical tipping point where generative video shifts from single-step generation to enterprise-ready applications in advertising, gaming, and interactive product demonstrations.
- a16z28 min
Health Tech Founders: The Future of Care Is Personalized, Proactive—and AI-Powered
Bryan Kim, Jonathan Swerdlin, Daniel Cahn
Jonathan Sorlin of Function Health and Daniel of Slingshot AI are launching AI-driven platforms that address critical gaps in physical and mental healthcare by transforming reactive medical models into proactive, data-centric prevention systems. Their products prioritize human experience over traditional metrics, utilizing autonomous tools to interpret complex biomarkers and foster therapeutic alliances without replacing human providers. This approach aims to scale access for millions by reducing systemic friction and burnout, ultimately lowering costs while empowering users to maintain autonomy and deepen genuine human connections.