Latest Interviews
Showing 316–330 of 1,573 transcripts.
Clear all filters- Goldman Sachs44 min
Memorial Sloan Kettering Cancer Center’s CEO on the Future of Cancer Treatment
Selwyn M. Vickers, Brian Robinson, Dr. Selwyn Vickers
Memorial Sloan Kettering leverages its vast biobank and dual expertise in computational oncology to drive a "golden era" of cancer treatment, where AI-driven predictive models and breakthroughs in immunotherapy have transformed survival rates for aggressive malignancies. Concurrently, the institution confronts rising youth cancer incidence and systemic health inequities by developing accessible genetic screening tools and deploying low-infrastructure immunotherapy protocols globally. These clinical and technological advances are grounded in a leadership philosophy that prioritizes professional excellence to dismantle socioeconomic barriers and improve care access for underserved populations.
- Y Combinator41 min
Ask These Questions Before Starting An AI Startup
Founder and alignment researcher Sam Altman warns that the imminent arrival of AGI within two to three years forces startups to radically rethink hiring, product design, and long-term strategy beyond traditional focus models. He argues that enterprises will soon bypass external SaaS providers by building internal software with AI, while consumer markets may shift from static apps to on-demand, AI-generated solutions that require new trust mechanisms like automated auditing. Ultimately, Altman urges founders to prioritize solving hard infrastructure problems and societal impact over immediate monetization, as the window to build defensible moats against commoditization and centralized control narrows rapidly.
- Milken Institute42 min
Who Will Win the Scramble for Global Talent? | Asia Summit 2025
Tiffany Ang, David Ha, Ichiro Miyoshi, Manjit Singh, Anupam Trehan
Industry leaders from Sun Life, Cisco, Sakana AI, and Manunouchi Innovation Partners convened to address the convergence of multi-generational workforces and AI-driven disruption in the global talent landscape. Panelists detailed strategic responses to U.S. visa fee hikes and the "war for talent," ranging from Cisco's rotational career pathways to Sakana AI's equity-based compensation for international AI researchers targeting Japan. The discussion highlighted that success in this evolving environment requires balancing deep technical skills with human-centric values, such as organizational purpose and collaborative workflows, to retain Gen Z talent and navigate shifting economic ecosystems.
- a16z27 min
Software is Eating Labor
The speaker outlines a fundamental shift in the global software economy where autonomous AI agents replace human labor to capture the $13 trillion U.S. wage market, effectively transitioning SaaS from digitizing records to executing end-to-end workflows. This transformation necessitates a move away from seat-based pricing toward outcome-based models, exemplified by pilots at companies like Zendesk and startups that deploy AI to perform tasks ranging from freight negotiation to debt collection. Consequently, venture capital efforts are pivoting to identify enterprises that can fully leverage this automation to monetize vast labor markets previously inaccessible to traditional software solutions.
- Milken Institute30 min
A Conversation with Saweetie: Harnessing Philanthropy to Build Financial Futures | Asia Summit 2025
Saweetie, Diamonté "Saweetie" Harper, Richard Lui
Multi-platinum rapper and entrepreneur Sweetie discusses her trajectory from baking cookies as a child to securing high-profile partnerships with brands like McDonald's and Calvin Klein while maintaining an authentic leadership style. She details the founding of the I See Baby Foundation, which aims to instill financial literacy in underrepresented youth by leveraging her personal financial lessons and her grandmother's advice. The conversation concludes with her strategic vision to build a decade-long infrastructure that teaches communities how to live educated, self-determined lives through a diverse, women-led team.
- a16z43 min
The Person Who Runs HR For 2 Million Federal Workers
Katherine Boyle, Scott Kupor, Greg Barbaccia
The administration is executing a sweeping overhaul of the federal workforce to secure national leadership in the AI race, projecting a reduction of 300,000 civilian employees while dismantling 43 years of hiring barriers to mandate technical skill testing. This strategy shifts performance evaluations toward a forced distribution model and replaces risk-averse culture with outcome-based efficiency, targeting a critical talent gap by recruiting early-career professionals and private sector executives for short-term secondments. Key initiatives include centralizing citizen data through a "One Government" portal, deploying generative AI tools like ChatGPT on government desktops, and restructuring contractor oversight to prevent cost sprawls driven by non-technical management.
- Milken Institute29 min
Singapore Defence Minister & Coordinating Minister for Public Services, Chan Chun Sing | Asia Summit
Chan Chun Sing, Laura Deal Lacey
Amidst global economic stagnation and rising political fragmentation mirroring the pre-World War II era, this event examines strategies to counteract protectionism through deliberate cooperation between governments and the private sector. Singapore's leaders outline four enduring competitive advantages—long-term policy consistency, progressive rule of law, strategic partnerships, and the SkillsFuture initiative—to demonstrate how investment in human capital can maintain social cohesion. The presentation concludes with a call for industry leaders to advocate for integrated global rules and prioritize workforce upskilling, ensuring that technological progress translates into shared prosperity rather than nativist backlash.
- All-In Podcast23 min
Rick Caruso on California’s Collapse: Broken Leadership, LA Wildfire Failures & the Fix
Rick Caruso, Karen Bass, Chamath, Jason
In the wake of the Palisades fires, developer Rick Caruso contrasts his private sector emergency preparations against the city's failures, blaming incompetent governance under Mayor Karen Bass for the destruction of 90% of the homes. Caruso argues that ideological politics have paralyzed local authorities, leading him to propose a competency-based administration that enforces zero tolerance for street encampments while simultaneously securing federal aid and infrastructure upgrades for rebuilding. As he evaluates potential political bids, Caruso emphasizes that California must prioritize practical solutions over political maneuvering to reverse systemic decay and restore the state's status as a national leader.
- All-In Podcast25 min
Arm CEO Rene Haas on AI: Nvidia Lessons, Intel’s Decline and the US-China Chip War
Rene Haas, Jensen Huang, David, Jason
Following a landmark September IPO that vaulted its valuation to $150 billion, Arm is leveraging its foundational IP to transition from a smartphone architecture provider into a strategic partner for Nvidia and a supplier for the emerging "Physical AI" robotics market. Chief Executive Officer Rene Haas is aggressively reshaping the company's global culture and engineering focus to accelerate speed-to-market, while explicitly navigating complex geopolitical frictions and supply chain constraints to maintain a unified global ecosystem. With its architecture underpinning critical advances in both data center training chips and energy-efficient endpoint inference, Arm is positioning itself to dominate a diverging semiconductor landscape where specialized hardware will define future AI capabilities.
- RAISE Summit20 min
Dr. Uri Yerushalmi, Co-Founder&CAIO, Fetcherr: How AI Driven Decision Maximizes Business Performance
Dr. Uri Yerushalmi, Uri Arushalmi
Uri Arushalmi, Chief AI Officer of Fetcher, presents Large Market Models as a quantitative evolution beyond current generative AI, utilizing deep learning on complex market data to simulate probabilistic dynamics rather than just processing text. These systems integrate internal and external data to run computational simulations that select policies maximizing revenue, successfully generating statistically significant revenue uplifts exceeding 10% in A/B testing. By enabling proactive anticipation of market shifts instead of reactive responses, this approach allows organizations to define competitive outcomes through structural market access rather than traditional operational metrics.
- RAISE Summit21 min
Alexis Ohanian, Founder, 776, Reddit & Victorien Tixier, CEO, ScorePlay: The Future of AI in Sports
Alexis Ohanian, Victorien Tixier, Vic
At an industry conference, Reddit co-founder Alexis Ohanian interviewed Scoreplay CEO Vic LaRosa to discuss how artificial intelligence will commoditize content production while elevating live sports as the premier vehicle for authentic, real-time human connection. Their dialogue highlighted Scoreplay's mission to replace legacy infrastructure with centralized AI automation for media asset management, a strategy designed to unlock global market reach through instant localization and data-driven camera placement. The conversation further emphasized a strategic pivot toward women's sports, where Ohanian argues that re-underwriting assets from first principles and leveraging digital-first storytelling will drive exponential valuation growth and reshape traditional league dynamics.
- RAISE Summit23 min
Atindriyo Sanyal, CEO of Galileo: Making Enterprise Gen AI “Reliable”
Galileo, an AI evaluation platform founded by a former Siri architect, addresses the critical "measurement problem" plaguing generative AI by introducing a specialized observability framework designed to productionize complex RAG and multi-step agents. The company's proprietary Luna models provide sub-200ms real-time inference for dynamic guardrails and qualitative-to-quantitative error analysis, effectively solving the latency and accuracy trade-offs that typically hinder enterprise deployment. This approach enables Fortune 500 organizations to move beyond basic statistics and systematically identify nuanced failure patterns in data quality, tool execution, and security across high-stakes workflows.
- All-In Podcast31 min
Inside the GLP-1 Gold Rush: Eli Lilly CEO on New Breakthroughs, Addiction & Mental Health, Pricing
Dave Ricks, Chamath, Jason, Friedberg
Eli Lilly CEO David Ricks has steered the company to an 860% market capitalization increase and record-breaking Mounjaro sales by leveraging a massive research workforce and aggressive manufacturing expansion to secure global dominance in GLP-1 therapies. While the firm faces capital shortages in the broader biotech sector, it is diversifying its pipeline beyond weight loss to address brain disorders and developing oral formulations to improve accessibility without compromising the high R&D reinvestment model Ricks defends. Personalized by Ricks' own successful treatment, the company balances aggressive clinical innovation with strategic supply chain controls to maintain its competitive edge against emerging international rivals.
- Goldman Sachs23 min
Will macro fuel more stock gains?
Analysts project the Federal Reserve will implement two additional rate cuts by year-end to address labor market risks, targeting a terminal rate near 3% as the economy navigates mixed employment signals and structural uncertainties. This easing cycle, expected to conclude by December 2026, aims to support risk assets and sustain growth while keeping inflation pressures contained amid a bearish outlook for oil and tariff impacts. Despite valuation concerns and skepticism regarding AI capital expenditure sustainability, the prevailing view suggests that resilient fundamentals and policy shifts will maintain upside momentum for the broader market through 2026.
- Goldman Sachs26 min
How Reliable is Economic Data?
Erica Groshen, Arthur Laffer, Alberto Cavallo, Joseph Briggs, Allison Nathan
Recent concerns regarding the reliability of U.S. economic data stem from funding cuts, a 15–20% staffing reduction at the Bureau of Labor Statistics, and the dismissal of its Commissioner by President Trump. Goldman Sachs research indicates that these operational constraints and declining survey responsiveness are increasing standard errors in key indicators like the CPI and JOLTS, creating a risk of data divergence. While current safeguards and institutional checks may prevent a total collapse of credibility, analysts warn that prolonged political interference and resource depletion could eventually erode market trust to the extent seen in Argentina.