Latest Interviews
Showing 1081–1095 of 1,549 transcripts.
Clear all filters- Goldman Sachs25 min
Richard A. Clarke, National Security Expert and Author
Richard A. Clarke, Andy Osment, Dick Clark
Former President's Counterterrorist Coordinator Dick Clark and co-authors analyze the realized threat landscape in their 2023 sequel *The Fifth Domain*, highlighting how the global NotPetya attack demonstrated that cyber operations intended for Ukraine can devastate U.S. infrastructure and the economy. Despite significant spending, the Defense Science Board and Government Accountability Office have identified critical vulnerabilities in the F-35 fighter jet and supply chains, while Russian information operations continue to exploit fragmented voting systems to suppress turnout ahead of the 2020 elections. Clark argues that stabilizing this critical instability requires sustained investment in defensive technologies like network segmentation and deception to outpace offensive capabilities and prevent accidental escalation into kinetic warfare.
- Goldman Sachs33 min
Kewsong Lee, Co-CEO of The Carlyle Group
In late 2018, Kyu-Song Lee assumed the co-CEO role at The Carlyle Group to lead the firm's transition from a partnership to a corporate structure, addressing a portfolio of 300 companies employing nearly one million people globally. Under Lee's strategic direction, Carlyle is integrating diverse leadership teams, where women now lead half of the firm's $250 billion in assets, while adopting a "every deal is a tech deal" mantra to navigate digital disruption. Looking ahead, Lee anticipates a low-growth macroeconomic environment and shifting U.S.-China trade dynamics, prompting the firm to expand private credit investments and prioritize operational improvements over financial engineering to ensure long-term resilience.
- Lex Fridman24 min
David Ferrucci: What is Intelligence? | AI Podcast Clips
The speaker defines intelligence as the capacity to predict outcomes in uncertain environments, arguing that true intelligence requires the ability to articulate reasoning and convince a community of its logical validity. While current algorithms excel at pattern recognition, they lack the shared cultural context and moral frameworks necessary to derive meaning or make value judgments, creating a gap between superficial prediction and deep understanding. Consequently, the event highlights the challenge of bridging this divide, as society demands AI that not only performs high-accuracy pattern matching but also facilitates the reasoned, moral decision-making inherent to human social constructs.
- Lex Fridman33 min
David Ferrucci: The Story of IBM Watson Winning in Jeopardy | AI Podcast Clips
Initiated in 2006 to commemorate Deep Blue's tenth anniversary, IBM's Watson Jeopardy! project successfully delivered a high-speed, self-contained question-answering system that integrated millions of data points across 3,000 CPU cores to defeat human champions. The system achieved this victory by employing a parallel processing architecture that generated up to 200,000 scores per query and utilized machine learning fusion to prioritize end-to-end performance over general natural language understanding. This strategic decision to solve specific benchmarks rather than pursue broad NLU proved critical, establishing a new standard for AI capabilities and demonstrating the viability of engineering integration for complex cognitive tasks.
- Goldman Sachs39 min
Dr. Denis Mukwege, Nobel Laureate and Founder of Panzi Hospital
Denis Mukwege, Dr. Dennis Mukwege
Nobel Peace Prize laureate Dr. Denis Mukwege operates Panzi Hospital in the Democratic Republic of Congo, where a comprehensive four-pillar model has treated over 50,000 sexual violence victims through integrated surgical, psychological, economic, and legal interventions. Facing systematic warfare tactics designed to dismantle community structures and the complicity of local authorities in mineral-fueling militia crimes, Mukwege has pivoted from exclusive clinical care to prominent global advocacy following a 2012 assassination attempt. By empowering survivors to transition from victims to activists through economic reintegration and the pursuit of non-retributive justice, the hospital challenges impunity while Dr. Mukwege continues to demand international action against the silence perpetuating these atrocities.
- a16z27 min
CRISPR 2.0 and the Future of Gene Therapies
The gene therapy sector is undergoing a paradigm shift from simple transgene addition to precise CRISPR-based editing, driven by recent FDA approvals and a pipeline projecting dozens of Phase 3 trials this year. Despite significant progress in developing base editors and expanding delivery vectors, the industry faces critical bottlenecks in manufacturing scalability and achieving organ-specific targeting without immunogenicity. Successful organizations are distinguishing themselves by combining rigorous engineering mindsets with interdisciplinary teams to optimize modalities and automate production for a future of millions of patients.
- The Economist36 min
Chimamanda Ngozi Adichie: identity, feminism and honest conversations
Chimamanda Ngozi Adichie, Sacha Nauta
Chimamanda Ngozi Adichie explores the fluid nature of identity and critiques the "own voices" movement for potentially flattening literature, arguing that storytelling requires inhabiting experiences beyond one's own. She explicitly rejects sensitivity screening and demands that authors write with honesty rather than being constrained by a fear of offense, while advocating for a feminism that actively includes men to dismantle harmful socialization. Ultimately, Adichie calls for a world where individual merit supersedes identity-based judgments, urging creators to humanize marginalized groups without sacrificing the complexity of their characters.
- Goldman Sachs23 min
Evan Spiegel, Co-Founder and CEO of Snap Inc.
Snap Inc. is capitalizing on accelerated revenue and user growth driven by Android product improvements, verticalized sales teams, and a premium content strategy that has boosted engagement among its core 13-to-34 demographic. The company differentiates its platform through high user retention rates, proprietary Distributed Device Machine Learning for on-device privacy, and a curated media model that contrasts with open social networks while expanding into gaming and augmented reality. Looking forward, leadership emphasizes sustainable business iteration and deliberate regulatory frameworks to position the platform as a hub for future visual communication and mass distribution.
- Goldman Sachs29 min
Brian Grazer – Academy Award-winning Producer
Legendary producer Brian Grazer built his career through "curiosity conversations" with industry titans, a strategy that led to his partnership with Ron Howard and the creation of Oscar-winning hits like *A Beautiful Mind* and the blockbuster *Apollo 13*. Leveraging personal trauma to destigmatize mental illness and reframing technical stories as human survival narratives, Grazer achieved record-breaking box office success while navigating high-stakes professional setbacks, such as his Oscar loss for *A Beautiful Mind*. Currently, Grazer channels his extensive industry experience into "Imagine Impact," a global incubator that mentors diverse storytellers from 90 countries to navigate the complexities of the modern streaming landscape.
- The Economist33 min
Climate Change: The Economist live Q&A
Oliver Morton, Sarah Collinson
*The Economist* launches its inaugural issue dedicated entirely to climate change, integrating analysis from all fourteen sections to cover diverse impacts ranging from Panama Canal droughts to Arctic permafrost thaw. Senior writer Oliver Morton and contributors argue that while individual lifestyle changes are insufficient, systemic solutions like decarbonized grids, targeted solar deployment, and liberal democratic reform offer the most viable path to mitigating long-term economic and ecological damage. Ultimately, the publication urges a strategic balance of intellectual pessimism regarding rapid reversals of the crisis with practical optimism focused on adaptation and gradual emission reductions to prevent the worst global outcomes.
- Goldman Sachs29 min
Episode 136: What’s It Really Like to Be a Goldman Sachs Intern?
Jake Seward, Catherine Dorvitz, Rebecca Shiner, Dane Holmes
Dane Holmes, Head of Human Capital Management, guided a Summer 2019 panel of interns, including upcoming analysts Catherine Dorvitz and Rebecca Shiner, to discuss the firm's strategic evolution toward holistic diversity and intentional living. Participants highlighted a critical shift in recruitment where 92% of interns value brand loyalty and a 17% priority on mental disconnection to prevent burnout, alongside an optimistic outlook on AI as a tool for enhancement rather than displacement. The session concluded by outlining the firm's investment in manager education and internal mobility to align with these evolving expectations for meaningful work-life integration.
- Lex Fridman38 min
Colin Angle: iRobot CEO | Lex Fridman Podcast #39
Over 29 years, iRobot has transitioned from lab experiments to selling 25 million consumer units like Roomba and Braava by leveraging Moore's Law and injection molding to overcome cost barriers. CEO Colin Engel argues that future robotics success depends on targeting frequent household burdens rather than creating artificial social companions, emphasizing that semantic understanding and local data processing are critical for scaling from cleaning to comprehensive home maintenance. This strategy aligns with the company's goal of placing a robot in every home to support an aging global population while maintaining strict privacy standards through on-device processing.
- Goldman Sachs28 min
US Sen. Tom Cotton – Author, "Sacred Duty"
U.S. Representative J.D. Cotton, a former Infantry platoon leader and Tomb of the Unknown Soldier guard, outlines his adversarial approach toward China, Iran, and Brexit while advocating for a merit-based green card system to replace chain migration. He critiques the 2015 Iran nuclear deal as a failure that enabled regional aggression and warns that undermining the 2016 UK referendum result would erode democratic trust. Looking ahead, Cotton calls for a Republican Party that bridges the gap between Washington insiders and grassroots voters through a focus on national security, worker protection, and robust civic education.
- Y Combinator29 min
Kirsty Nathoo - Managing Startup Finances
Founders are advised to track core financial metrics like burn rate and runway weekly to maintain a "default alive" trajectory toward profitability, using tools like Trevor Blackwell's calculator to model realistic scenarios. The presentation warns against underestimating expenses, misclassifying labor costs, or hiring prematurely, emphasizing that scaling before product-market fit significantly increases failure risk. To secure optimal fundraising leverage, founders should aim for sustained revenue growth on existing capital while reserving Series A financing for when detailed forecasts and proven traction are available.
- Goldman Sachs20 min
Tyra Banks – CEO of The Tyra Banks Company
Tyra Banks leverages her mother's strategic oversight to transform early modeling rejections into a pioneering career as the first black Sports Illustrated Swimsuit cover model and Victoria's Secret Angel. Building on this foundation, she evolved from a runway subject into a media mogul by conceiving *America's Next Top Model* and applying Harvard and Stanford business principles to define modern personal branding. Banks now focuses on leadership and sustainable business scaling by emphasizing real-time feedback and the intentional celebration of diverse beauty traits.