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  1. All-In Podcast48 min

    Ted Cruz: Trump's First Week, Texas vs. California, Immigration, DOGE, Greenland

    Ted Cruz, Trump, Senator Ted Cruz, Chamath, Jason, Friedberg

    Senator Ted Cruz joined the All In Podcast live from President Donald Trump's inauguration to detail the incoming administration's aggressive strategy of approximately 100 executive orders focused on border security, energy deregulation, and tax extensions. Cruz contrasted Texas's population growth and economic model driven by low regulation with California's fiscal struggles, while advocating for specific reforms such as the Department of Government Efficiency, term limits, and expedited FDA approvals. The discussion also highlighted the administration's national security objectives, including renegotiating the Panama Canal and potentially acquiring Greenland, alongside a critique of welfare incentives and socialized healthcare systems.

  2. Milken Institute1h 1m

    The Emerging World of Opportunities: Insights from MI's Global Opportunity Index | Global Conference

    Carole Biau, Jarred Glansbeek, Richard Jadulan, Leticia Jáuregui Casanueva, Toyin Sanni, Carol Beo, Jared Glanzbeck

    The Milken Institute Global Opportunity Index panel evaluated investment landscapes across Sub-Saharan Africa, Latin America, and Asia, highlighting specific regional drivers such as Nigeria's administrative reforms, Mexico's nearshoring potential, and the Philippines' regulatory liberalization. Key speakers Jared Glanzbeck, Dr. Toyin Sani, and Leticia Haureyi-Casanueva emphasized that undervalued emerging markets offer significant equity entry points when investors overcome perception gaps through local partnerships and targeted focus on gender diversity and climate resilience. The discussion concluded that strategic capital allocation into human capital and sustainable infrastructure remains critical for capturing the substantial foreign direct investment inflows correlated with improved institutional frameworks.

  3. Milken Institute56 min

    Inclusive Capitalism: Unleashing Growth in the Global Economy | Global Conference 2024

    Troy Duffie, Nisha Biswal, Roger Ferguson, Carla Harris, Martin Nesbitt

    This event convened economic and financial leaders to analyze the U.S. job market, evolving inflation dynamics, and the strategic expansion of private credit and development finance in response to global supply chain shifts. Panelists redefined investment frameworks through "Capitalism 3.0," integrating ESG metrics and diversity initiatives into core risk management while addressing the Series A funding gap for entrepreneurs of color. Key outcomes included the U.S. Development Finance Corporation's doubled mandate to $60 billion and the launch of Morgan Stanley's Next Level Fund, which pairs capital with operational expertise to support inclusive growth and stable returns.

  4. Milken Institute51 min

    Credit Investors Taking the Reins | Middle East and Africa Summit 2024

    Michael Piwowar, Sandeep Chandak, Michael Gross, Zia Uddin, Orla Walsh, Mike Pivovar

    A panel of industry leaders outlined the divergent trajectories of global private credit markets, noting Asia's rapid expansion into a mature source of alpha while the U.S. market faces yield compression and systemic stress from high leverage in the upper-middle sector. Speakers detailed strategic shifts toward labor-intensive origination, specialized financing for infrastructure gaps, and the regulatory necessity of robust legal frameworks to protect investor interests. The discussion concluded that future success depends on diversified, multi-strategy approaches capable of navigating retailization risks and generating equity-like returns as the industry transitions from a double-digit return era to a more normalized competitive landscape.

  5. Dwarkesh Patel1h 1m

    Tyler Cowen — The #1 bottleneck to AI progress is humans

    Tyler Cowen, Jason Crawford, Heike Larson

    Economist Tyler Cowen argues that AI-driven economic growth will be constrained by non-intelligence bottlenecks such as labor shortages and regulatory inertia, resulting in a modest 0.5% annual boost rather than explosive takeoff. He posits that future success depends on scarce bundles of talent and organizational culture rather than raw intelligence, while noting a divergence where peak human capability is rising even as the middle of the distribution deteriorates. Furthermore, Cowen anticipates the fragmentation of organized social movements like Effective Altruism and advocates for writing primarily for AI training data to secure knowledge accumulation in a shifting geopolitical landscape.

  6. 20VC with Harry Stebbings1h 6m

    Dan Gill, CPO @Carvana: The Most Wild Story in Public Markets | E1243

    Dan Gill, Harry Stebbings

    Carvana CEO Dan Erwin outlines the company's recovery from a 99% market cap valuation drop to a $50 billion resurgence, driven by a leadership team that retained 90% of its senior members since 2019 and prioritized radical internal transparency. This stability supports a rigorous hiring philosophy focused on technical horsepower and intrinsic drive, which enabled the organization to restructure into eight cross-functional units while implementing vertical integration strategies that capture profit pools in financing and logistics. Leveraging deterministic AI systems for real-time personalized offers, the firm maintains a product strategy that rejects industry hype in favor of unit economics, aiming to automate routine customer service tasks while keeping high-complexity transactions under human specialist oversight.

  7. Milken Institute48 min

    The Evolving Landscape of Private Markets | Middle East and Africa Summit 2024

    Laura Merlini, Lauren Goodwin, Klaus Hommels, Scott Spielvogel, David Steinbach, Andrew Weinberg

    The event examines how shifting macroeconomic trends, including lower interest rates and the $90 trillion generational wealth transfer, are driving capital into private markets while redefining exit strategies and liquidity structures. Speakers detailed critical convergence points where defense tech, AI implementation, and infrastructure real estate intersect with evolving regulatory frameworks in Europe and the US. These discussions project a resilient 2025 outlook where public and private market mechanisms merge to support middle-market growth and operational innovation.

  8. Milken Institute53 min

    Asset Management: Vying for the Competitive Edge | Middle East and Africa Summit 2024

    Michael Piwowar, Todd Boehly, Lawrence Golub, Martin Horne, Camilla Languille, Stephanie Rader, Mike Pivovar

    Leading global investors, including Mubadala, Eldridge, Golub Capital, and Goldman Sachs Asset Management, discussed strategies for navigating a shifting landscape characterized by the convergence of artificial intelligence and energy infrastructure needs. The panel highlighted specific tactical shifts such as Mubadala's launch of the MGX AI fund, Eldridge's opportunistic crisis lending, and the region's urgent demand for private credit to support Saudi Vision 2030. Additionally, participants analyzed geopolitical diversification away from China toward India and emphasized the Middle East's role as a critical hub for attracting global AI talent and scaling sustainable technology investments.

  9. All-In Podcast1h 16m

    The All-In Holiday Spectacular

    Chamath, Jason, Aaron Levie, Alex Botez, J. Cal, David Sacks, David Friedberg

    In this 2024 year-in-review summary, hosts David Sacks, Chamath Palihapitiya, and David Friedberg analyze the political triumph of Donald Trump alongside the technological dominance of NVIDIA, Elon Musk, and GLP-1 drugs. The discussion details the decade's defining winners, including SpaceX and Palantir, while critiquing failures ranging from Boeing's Starliner to the perceived elder abuse of President Biden. Looking ahead, the panel forecasts a 2025 marked by fiscal reform through the Department of Government Efficiency and the transformative impact of artificial intelligence on global prosperity.

  10. Milken Institute54 min

    Global Cities in a New Light | Middle East and Africa Summit 2024

    Natasha Turak, Eric Garcetti, Goodwin Gaw, Nikhil Goel, Yasseen Mansour

    Speakers from Archer Aviation, global city leaders, and real estate investors discussed strategies to overcome urban congestion through electric air taxis, high-density housing reforms, and sustainable infrastructure projects like Badia in Egypt. Key figures highlighted the critical need to balance ambitious greenfield experiments such as NEOM with practical financial viability, while advocating for regulatory pathways that bypass entrenched NIMBYism. The dialogue concluded with a consensus that successful future cities require integrated planning combining vertical mixed-income development, autonomous transport corridors, and organic growth models to ensure long-term livability and economic sustainability.

  11. Jane Street1h 3m

    Horace He: Building Machine Learning Systems for a Trillion Trillion Floating Point Operations

    Horace He

    Meta compiler engineer Horace He analyzes the dramatic consolidation of AI infrastructure, noting that modern model training now requires massive power resources and billions in capital to achieve state-of-the-art performance. He details how the industry has transitioned from simple imperative execution to complex compiler strategies like FlexAttention and `torch.compile`, which are essential for managing the critical balance between GPU compute and memory movement. Ultimately, He argues that the primary challenge in this field is shifting focus from pure optimization to designing robust programming models that allow developers to reliably express complex performance trade-offs in large-scale distributed systems.

  12. Milken Institute1h 14m

    Navigating a Changing Global Economy | Middle East and Africa Summit 2024

    Laura Deal Lacey, Michael Milken, His Royal Highness Prince Turki Al Faisal Al Saud, Makhtar Diop, Mohamed Mansour, Alan Schwartz, Prince Turki Al Faisal Al Saud

    Held in Abu Dhabi in December 2024, the 6th Annual Middle East and Africa Summit convened global leaders from the Milken Institute, the International Finance Corporation, and the Mansour Group to mobilize capital toward healthcare, economic development, and environmental sustainability. The event highlighted a strategic pivot where emerging markets are transforming from passive capital providers into technology hubs capable of bridging the gap between the aging Global North and Africa's young, growing workforce. Participants addressed critical investment barriers such as regulatory uncertainty and currency mismatches by proposing blended finance models and de-risking strategies to unlock trillions of dollars in private and philanthropic resources.

  13. Milken Institute1h 1m

    Decoding Disease: Can Genetics Unlock New Interventions? | Future of Health Summit 2024

    Conor Hale, Colleen Campbell, Lon Cardon, Bernard Kwabi-Addo, Benjamin Neale

    Experts highlight that while genomic knowledge has expanded to 12,000 identified variants, translating these discoveries into clinical care remains hindered by insurance barriers, provider literacy gaps, and biased data representation. To overcome these bottlenecks, the field is increasingly leveraging artificial intelligence for tumor heterogeneity analysis and shifting toward deconstructing common diseases into rare, monogenic subsets for targeted therapies. With sequencing costs dropping to roughly $200, stakeholders anticipate widespread population screening programs and systematic variant analysis across human diseases becoming feasible within the next decade.

  14. Milken Institute53 min

    Health Care of the Future | Future of Health Summit 2024

    Michael Milken, Alex Azar, Buddy Carter, Diana DeGette, Renee Wegrzyn

    The event detailed how ARPA-H and legislative initiatives like "Cures 2.0" are addressing systemic healthcare challenges by funding high-risk biomedical innovations and ensuring pharmaceutical independence. Key figures including Rep. Diana DeGette and Rep. Chris Carter highlighted strategies to reform Medicare Advantage payment models and repatriate drug manufacturing to counter supply chain vulnerabilities. The panel concluded with a call for increased federal investment in translational science and a broader call for business leaders to enter government to sustain the pace of medical breakthroughs.

  15. Milken Institute1h 11m

    Global Collaboration to Eradicate Women’s Cancers | Future of Health Summit 2024

    Alice Park, Usman Malami Aliyu, Danielle Carnival, Dave Fredrickson, Roberta Lipson, Gemma Peters

    Global cancer leaders convened to address the projected doubling of incidence in low- and middle-income countries by implementing diverse strategies ranging from Nigeria's mobile screening vans and mobile PCR labs in China to the UK's data-driven risk assessment partnerships. These initiatives prioritize overcoming structural inequities in treatment access, financial barriers, and clinical trial participation through innovations like AI-driven imaging, drug repurposing, and targeted care navigation programs. Ultimately, the consensus emphasizes that sustainable national cancer control plans must integrate geopolitical cooperation and equity-first designs to prevent the fragmentation of global research and ensure effective prevention for the most vulnerable populations.