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  1. All-In Podcast1h 19m

    E171: DOJ sues Apple, AI arms race, Reddit IPO, Realtor settlement & more

    Chamath Palihapitiya, David Sacks, David Friedberg, Jason Calacanis

    The U.S. Department of Justice filed a Sherman Act lawsuit alleging Apple's App Store and ecosystem strategies constitute anti-competitive monopolies, a move that prompted 3% market losses and sparked debate among legal experts regarding interoperability mandates versus product integration. Simultaneously, major market shifts are underway as the National Association of Realtors agrees to a $418 million settlement that will force buyers to pay agent commissions directly, while Microsoft's strategic acquisition of Inflection AI's talent signals deepening competition in the artificial intelligence sector. These legal and structural changes occur alongside renewed investor optimism following Reddit's successful IPO and ongoing discussions about the Federal Reserve potentially cutting interest rates later this year.

  2. All-In Podcast1h 19m

    E148: McCarthy ousted, border chaos, Cruise's robotaxi "accident" & more

    McCarthy, Cruise, Jason, Chamath, Calacanis, Friedberg, Webster, Chaffetz, Abbott, Biden, Trump, Adams, David Sacks

    The hosts corrected prior financial estimates for Airtable, clarifying its current valuation sits between $7 and $8 billion with approximately $500 million in ARR after consulting CEO Howie Liu. The discussion also detailed Speaker Kevin McCarthy's ousting by a bipartisan vote seeking to replace continuing resolutions with twelve individual spending bills to curb federal debt. Further segments analyzed accelerating U.S. border encounters, advocating for a return to strict asylum vetting and satellite surveillance, while contrasting the public's low risk tolerance for autonomous vehicles against their proven safety potential.

  3. All-In Podcast1h 28m

    E147: TED goes woke, Canada's Nazi blunder, AI adds vision, plus: who owns OpenAI?

    Coleman Hughes, Sam Altman, David Sacks, Friedberg

    Coleman Hughes describes a conflict with TED following his talk on colorblindness, alleging that staff censorship suppressed the video's visibility to appease ideological objections and prevent the release of a debate. He argues this incident illustrates how institutional capture occurs when employee values override leadership intent, leading to the marginalization of viewpoints like those regarding racial identity and policy. Additionally, the discussion expands to critique perceived incompetence in Western political leadership regarding historical contexts in Ukraine and analyzes emerging trends in AI, including OpenAI's valuation strategies and the potential for language models to replace traditional operating systems.

  4. a16z1h 2m

    More Than a Game: Why Are We Obsessed With Sports?

    Que Gaskins, Robin Arzón, Brandon Brown, Nan Wang

    This discussion unites sports industry leaders to define "swagger" as the intersection of authenticity and greatness, while analyzing how the sector is shifting toward athlete empowerment, data-driven NIL monetization, and Web3 ecosystems. Participants detail operational breakthroughs from companies like Sleeper and Peloton, illustrating how social-first design and values-driven hiring can disrupt stagnant markets and redefine demographic engagement. By examining personal narratives of overcoming adversity alongside specific case studies on branding and technology, the dialogue highlights the transition from traditional performance metrics to holistic community building and creator-owned digital economies.

  5. a16z1h 10m

    Evolve or Die: The Future of the Creative Process, Artist Authenticity, and the Value of the Music

    Doug E. Fresh, Dre Lyon, Nicole Wyskoarko, Piff Marti

    Doug E. Fresh, Kool Keith, Piff, and Dr. Dre convened to discuss the critical necessity of evolving through technology while maintaining artistic integrity to survive the modern music industry. The panelists detailed how early adoption of tools like the MPC 3000 and YouTube University enabled self-reliance, while highlighting recent legal shifts that transformed music catalogs into valuable asset classes managed through venture capital funds. Ultimately, the speakers argued that despite the rise of AI as a creative co-pilot, human authenticity and emotional connection remain the only irreplaceable drivers of generational wealth and cultural relevance.

  6. All-In Podcast1h 27m

    E123: Trump indictment, de-dollarization, should VCs back Chinese AI? RIP Bob Lee

    Trump, Bob Lee, Calacanis, Chamath Palihapitiya, David Sacks, David Friedberg

    The panel dissected Mahalo's collapse following Google's Panda update to critique the dangers of content farming, while simultaneously debating the political motivations and legal precedents surrounding Donald Trump's New York hush money indictment. Economists and investors then analyzed the risks of US de-dollarization through China-Brazil trade deals and the escalating fiscal crisis driven by unfunded public pensions in Chicago. Finally, the discussion shifted to public safety failures in San Francisco and the geopolitical strategy of Saudi venture capital, contrasting constructive engagement policies with national security concerns regarding Chinese AI investment.

  7. Milken Institute1h 6m

    Creating Community Wealth and New Revenue: Public Assets Workshop

    Matt Horton, Ben McAdams, Dina Blaes, Jason Foster, Shayne Kavanagh, Joe Minicozzi, Dan Tangherlini, Natalie Cohen

    The Milken Institute Center for Regional Economics convened a public finance forum where panelists including former Salt Lake County Mayor Ben McAdams and Urban Planner Joe Minicozzi argued for "Urban Wealth Funds" to transform underutilized public assets into revenue generators that reduce reliance on regressive tax bases. While the session highlighted a Salt Lake County study revealing $12 billion in potential transit-corridor value, speakers like Dina Blaze and Dan Tangerlini emphasized that equitable implementation requires overcoming political barriers and establishing community equity endowments to prevent resident displacement. Experts concluded that local governments must adopt proactive asset valuation and flexible governance structures to legally function as corporate-like entities that capture public wealth for direct community reinvestment.

  8. Milken Institute1h 9m

    Deep Dive: Deployment of High Demand Community Infrastructure Projects

    Dan Carol, Bryan Borlik, Rachel Halfaker, Donnel Baird, Rob Day, Bill Lee, Patrick Meyers, Michelle Moore, Matt Petersen, David Guilford, Adam Fried, Robbie Jones

    The Economic Development Administration awarded a grant to the Milken Institute and RCAP to launch a pre-development training accelerator designed to equip rural and underserved communities with the technical capacity to make infrastructure projects shovel-ready. A diverse panel of experts including representatives from the Trust for Public Lands, Groundswell, and Spring Lane Capital highlighted the critical need for zero-percent match requirements, community-paid participation stipends, and granular data targeting to overcome traditional grant-writing barriers. These initiatives aim to transform one-time federal funding into sustainable local wealth by pairing financial capital with technical assistance to scale projects ranging from broadband and green infrastructure to urban decarbonization.

  9. Milken Institute58 min

    Antibiotic Resistance and Chronic Disease: Understanding the Challenges and Some Possible Solutions

    Amanda Jezek, Jonathan Daniels, David Greenberg, Thomas Heyman, Kathy Talkington, Mark Williams, Tom Heyman

    Hosted by Faster Cures in partnership with the Infectious Disease Society of America and other key organizations, this webinar examined the critical market failure hindering new antibiotic development and highlighted its severe impact on cancer, cystic fibrosis, and transplant patients. Panelists presented data showing thousands of annual deaths from antimicrobial resistance while advocating for the "Pasteur Act," a policy designed to de-link financial rewards from sales volume to incentivize the creation of novel drugs for critical pathogens. The event concluded by urging stakeholders to share personal stories and sign a letter to Congress to drive legislative action and secure funding for both antibiotic stewardship and research.

  10. Milken Institute1h 26m

    Equity in Infrastructure Development: The Digital Divide

    Jackie Botts, Michael P. Anderson, Carolyn McIntyre, Sunne McPeak, Alexandra Rosen, David Lesher, Matt Horton

    Co-hosted by CalMatters and the Milken Institute, a recent forum examined the critical role of high-speed broadband in addressing California's digital divide and promoting workforce equity. The discussion highlighted that while the state approved a $6 billion investment package to fund middle-mile infrastructure and last-mile expansion, significant barriers including high costs, digital literacy gaps, and inefficient permitting processes continue to hinder access for 2 million disadvantaged households. Experts emphasized that achieving true connectivity requires a hybrid approach combining fiber and wireless solutions, alongside public-private partnerships and targeted outreach to communities skeptical of traditional internet service providers.

  11. Milken Institute1h 30m

    California: The Post-COVID Future of Work

    Jackie Botts, Sarah Bohn, Rob Lapsley, David Lesher, Matt Horton, Aleida Ramirez, Lorena Gonzalez

    Co-hosted by CalMatters and the Milken Institute's California Center, this panel examined how California's post-pandemic economic recovery is exacerbating racial and income inequalities despite a $75.7 billion budget surplus. Moderator Jackie Botts facilitated discussions among policymakers like Assemblymember Lorena Gonzalez, who advocated for treating child care as public infrastructure, reforming the EDD to prevent fraud, and prioritizing trade apprenticeships over traditional college degrees. The event concluded with a consensus on structural reforms for 2030, including unionized service-sector wages, expanded safety nets, and legislative changes to support remote work and essential workers who cannot telecommute.

  12. Milken Institute1h 2m

    Lessons Learned from COVID-19: Are There Silver Linings for Biomedical Innovation?

    Esther Krofah, Francis Collins, Richard Moscicki, Ellen Sigal, Janet Woodcock

    Hosted by Faster Cures, a webinar convened NIH officials and industry leaders to analyze the COVID-19 pandemic's acceleration of biomedical innovation, highlighting achievements such as the ACTIV partnership's master protocols and the RADx initiative's diagnostic scaling. The discussion detailed how the crisis forced a shift toward competitive collaboration, decentralized trials, and the successful achievement of diverse vaccine trial enrollment, while simultaneously exposing critical infrastructure gaps in clinical trial execution and real-world data integration. Panelists concluded with a consensus that emergency-driven reforms must be institutionalized through permanent policy changes and public-private partnerships to sustain preparedness for future health threats.

  13. Milken Institute1h 1m

    Walking the Talk: Investing in the Future of Black Banks, Entrepreneurship, and Opportunity

    Eugene Cornelius, Jr, Henry Childs II, Emanuel Friedman, Tracy Gray, Joseph Haskins, Jr., Aron Betru

    This panel examines the systemic barriers preventing Black entrepreneurs from accessing capital and reveals that closing the racial wealth gap could unlock $1.6 trillion in US economic potential. Experts advocate for a strategic shift from traditional inclusion to innovation by leveraging $9 billion in government-funded preferred stock to mobilize $90 billion in community lending and aggregating pension capital for diverse asset managers. The discussion concludes with a call to build a self-sustaining minority economy driven by global export opportunities, artificial intelligence, and direct financing models rather than reliance on historically exclusionary systems.

  14. Milken Institute1h 2m

    The Next Decade: How to Manage Disruption

    Scarlet Fu, Beth Ferreira, Gregg Lemkau, Brian Sheth, Chris Stadler

    Leading investment experts discuss how the pandemic has accelerated the commoditization of technology and triggered a 28-year high rate of operational disruption, forcing a permanent shift toward hybrid work models and virtual deal-making. The panel highlights unprecedented capital deployment creating a valuation barbell that distorts traditional buying opportunities, while specific sectors like biotech, digital health, and software modernization drive innovation amidst concerns over social cohesion and inequality. Future market dynamics are expected to evolve into a hybrid public exit strategy combining IPOs, SPACs, and direct listings, with management resiliency and ESG integration serving as the primary metrics for long-term investment viability.

  15. Milken Institute1h 7m

    Technology and the Opening of Trade

    Eugene Cornelius, Marianne Jason, Mary Yang, Kevin Smith-Ramos, Fred Hogberg

    A panel of experts from the OECD, Canada, Mexico, and the US Ex-Im Bank emphasized that modernizing trade agreements like USMCA and reforming the WTO are critical to helping SMEs overcome financing barriers and digital divides. The discussion highlighted a divergence in national strategies, contrasting the US's fragmented agency approach with Canada's consolidated model while stressing the need for domestic policies to bolster workforce readiness alongside international market access. Ultimately, participants agreed that sustainable global growth requires addressing social inequities and leveraging digital tools to democratize trade participation for smaller enterprises and developing economies.