Latest Interviews

Pat Grady: Sequoia Partner on Investing Lessons from Doug Leone, Roelof Botha and Alfred Lin | E1174

Pat Grady, Doug Leone, Roelof Botha, Alfred Lin, Harry Stebbings

Pat and Doug Leone of Sequoia Capital prioritize founders with deep domain expertise and intense motivation, utilizing a "vector" assessment to select exceptional talent over favorable market conditions alone. The firm distinguishes its portfolio management through active value creation, exemplified by strategic interventions at companies like ServiceNow and HubSpot, while maintaining a "Day One" culture to mitigate internal arrogance. By combining rigorous due diligence with a specialized operator team and long-term harvesting strategies, Sequoia aims to compound returns by backing leaders who can navigate scaling challenges and unlock trillions in market value.

A Conversation with OpenAI COO Brad Lightcap | Global Conference 2024

Brad Lightcap, Julia Boorstin

OpenAI is accelerating enterprise adoption through strategic partnerships with entities like Stack Overflow and major publishers while demonstrating tangible operational efficiencies, such as Klarna's reduction of support ticket resolution times by 82%. Despite rapid integration into 92% of Fortune 500 companies, leadership warns that energy supply chain constraints and regulatory caution pose significant hurdles to scaling the infrastructure required for future multimodal models. The organization is shifting toward an iterative deployment strategy to smooth the transition from text-based tools to collaborative AI teammates, aiming to foster workforce familiarity while mitigating the risks of insufficient economic growth.

Conversation with Federal Reserve Bank of New York President & CEO John Williams | Global Conference

John Williams, Brooke Masters

Federal Reserve Chair John Williams characterizes the U.S. economy as transitioning toward a sustainable 2% inflation target, noting that restrictive monetary policy will persist until data confirms balanced progress on employment and price stability. While recent supply-side gains from labor participation and immigration supported 3.1% GDP growth, forecasts indicate a moderation to 2-2.5% as consumer spending diverges between affluent and lower-income households. Williams further warns that geopolitical volatility, potential labor market impacts from artificial intelligence adoption, and demographic shifts signal an end to the era of low economic uncertainty.

The core of effective altruism & how to argue for it | Benjamin Todd (2020)

Benjamin Todd, Arden Koehler, Rob Wiblin, Ben Todd

Ben Todd and Arden Kaler clarify that effective altruism is an intellectual project dedicated to maximizing the common good through impartial analysis, rather than a rigid mandate for specific charitable tactics or immediate donations. They argue that the movement prioritizes existential risks and long-termism over traditional global health efforts due to the massive impact differences between various interventions, while acknowledging the need for rigorous data to validate claims regarding the spread and identifiability of high-reward actions. The discussion further addresses common misconceptions and objections by reframing the community's goals around answering which problems are most pressing, thereby correcting public conflation of effective altruism with a narrow set of behavioral norms.

Leader of the package: Amazon turns 30

Rosie Bloor, Guy Scriven, Lena Shipper, Josh Spencer

At its 30th anniversary, Amazon surpassed a $2 trillion market cap while facing intensified antitrust litigation from the US Federal Trade Commission over its dominant retail and cloud positions. Simultaneously, India's National Testing Agency suspended its head and ordered retests for millions after a medical entrance exam scandal revealed massive cheating that exposed deep social mobility gaps. In a separate economic shift, China's durian imports from Southeast Asia tripled to $7 billion, transforming the fruit into a luxury commodity while raising geopolitical concerns regarding trade dependency.

A Conversation with Issa Rae & Sherrese Clarke Soares | Global Conference 2023

Issa Rae, Sherrese Clarke Soares, Ari Melber

Harborview Capital, in partnership with Apollo Global Management, leverages a "content is queen" thesis to direct up to $1 billion toward media assets led by people of color, specifically targeting Black women and diasporic communities in Newark, New Jersey. Issa Rae and Charisse Clark-Soros discuss a seismic industry shift where creators are reclaiming ownership and demanding data transparency to replace the opaque metrics of streaming platforms. The dialogue underscores a strategic pivot toward hyper-local authenticity, arguing that specific, culturally rooted storytelling drives global engagement and justifies redirecting capital to diverse entrepreneurs.

Avi Eyal: Making $2.3BN on Monday, Stripe & PillPack from Entrée Capital MP | E1173

Avi Eyal, Harry Stebbings

Avi Aviram of Entrez describes an investment strategy prioritizing team quality and founder insideness to generate massive returns, exemplified by a $1.5 billion distribution from a $15 million stake in Monday.com. The firm executes a concentrated portfolio approach that leads follow-on rounds while enforcing strict exit discipline to secure gains before public market volatility. Beyond financial metrics, Aviram addresses the institutionalization of venture capital and calls for a new generation of Israeli leadership to address societal fragmentation and geopolitical challenges.

The artistry is actually in that interface between the human and the technology itself.

The speaker argues that while artificial intelligence will significantly assist with backend development and API writing, it cannot fully automate the creative interface between humans and technology where true software artistry resides. By leveraging strongly typed systems and natural language to translate requirements into specifications, AI serves as a powerful tool that augments human productivity rather than replacing it. Ultimately, the event emphasizes that defining the fundamental scope of products remains a critical human responsibility that transcends mere code generation.

Taking stock: Can the US rally continue?

David Kostin, Alison Nathan

Goldman Sachs U.S. Equity Strategist David Kostin raised the firm's year-end S&P 500 target to 5,600, citing resilient earnings expectations despite the index's heavy reliance on just five AI-driven stocks that accounted for 60% of year-to-date gains. While forward valuations remain near historic highs at 21 times earnings, Kostin projects a slight multiple compression to 20.5 times as market participants pivot from AI euphoria to scrutiny over the timing of revenue realization in upcoming earnings reports. The outlook further incorporates potential election-related volatility and tariff uncertainties, with the primary downside risk identified as a rapid valuation correction if AI investment returns fail to materialize alongside robust corporate share repurchase demand.

Matt Clifford: The Bull & Bear Case for China's Ability to Challenge the US' AI Capabilities | E1172

Matt Clifford, Harry Stebbings

As the era of diminishing returns on raw model scaling approaches, the speaker argues that future value will derive from novel algorithms, multimodal data, and specific product innovations rather than mere compute expansion. While US semiconductor controls and strict Chinese regulations threaten to create divergence in global AI development, the UK's lighter regulatory environment and deep talent pool position it as a superior hub for this next generation of asymmetric, idea-driven startups. The discussion concludes that ambitious founders should capitalize on this window to build AGI-scale companies, noting that success relies more on the performance of top individuals and strategic risk-taking than on traditional team dynamics or financial experience.

You should probably still learn how to code.

A recent analysis of Large Language Models reveals that their logical development stems from processing code repositories like GitHub, providing empirical proof for the long-suspected link between programming and increased human intelligence. While the ultimate goal of computing is to eventually eliminate the need for manual coding, experts argue that learning to write code remains essential today because the cognitive challenge of programming itself enhances intellectual capacity. This emerging data transforms a historical practitioner belief into a validated conclusion, urging continued education in coding despite advancements in AI-generated software.

Remarks by the President of Argentina Javier Milei | Global Conference 2024

Javier Milei, Conrad Kiechel

President Javier Milei assumed office in Argentina to confront a 200% inflation crisis and 41% poverty rate by implementing a libertarian platform that secured a 20-year-first fiscal surplus within five months. His administration reversed a historical trajectory of collectivism by cutting public spending, repearing hundreds of laws, and dismantling unnecessary agencies to unlock the nation's potential for economic convergence. Milei now positions Argentina as a global investment hub, urging international leaders to support free-market principles as the essential path to lifting 60% of the population out of poverty.

Large-cap investing with Jennison Associates’ Kathleen McCarragher

Kathleen McCarragher, Betsy Gorton

Kathleen McCarriger, the Head of Growth Equity at Jenison Associates, discusses the firm's fundamental research approach and its substantial success in identifying structural growth opportunities, exemplified by a transformative 2016 Nvidia investment. Leveraging a team with an average of 25 years of industry experience, McCarriger distinguishes current AI spending from historical bubbles while emphasizing a 3-to-10-year client horizon that prioritizes active management outperformance. She further attributes the firm's enduring culture to the legacy of late founder Sig Sigalis and a strict discipline in adhering to known fundamentals rather than speculative trends.

Marc Andreessen on Inventing The Internet Browser (How We all Access the Internet)

Marc Andreessen, Ben Horowitz

Drawing from Mark Andreessen's journey from a rural Wisconsin farm to the University of Illinois, the event details the 1992-1993 creation of Mosaic, which defied the era's academic consensus by introducing a graphical web interface that prioritized openness over binary efficiency. Following a contentious split with the University of Illinois and its commercial licensee Spyglass, Jim Clark recruited Andreessen to found Netscape in 1994, catalyzing a legal battle and a Microsoft counter-offensive that ultimately collapsed Spyglass's business model while democratizing global internet access. The narrative extends beyond this history to warn of current risks, contrasting the successful "hyperstition" of early web pioneers with modern fears of regulatory capture and the incompetence of established experts in predicting technological evolution.

Mark Suster, Upfront Ventures: Investing in Space, Defense, & Exit Opportunities

Mark Suster, Molly O'Shea

Mark Suster and Upfront Ventures articulate a strategy centered on disciplined seed and early-stage investing to navigate a private equity landscape where valuation spreads have narrowed, forcing acquirers to focus on $100M to $500M targets rather than billion-dollar exits. Their approach utilizes a barbell fund structure that avoids overvalued Series A/B rounds while prioritizing founder-centric deals in sectors like space, defense, and robotics to mitigate the risks of an increasingly difficult IPO environment. By targeting companies with exceptional product economics and long-term founder commitment, the firm aims to position its portfolio for acquisition when market conditions correct, anticipating a surge in aggressive buyouts within the next two to three years.