Latest Interviews

CDC Director Robert Redfield: 'Opioid Epidemic is the public health crisis of our time'

Robert Redfield, Rick Berke

This event details a strategic review of an organization facing significant funding uncertainties and access barriers while pivoting toward social justice, independent scientific research, and multi-year capital market transitions. Key figures addressed the contradiction between current resource limitations and plans to expand operations through federal partnerships over a projected three-year timeline to better manage global crises. Despite ambiguous historical anchors and disjointed narrative segments, the discussion concluded with a commitment to advancing systemic reforms and developing spiritual leadership capabilities among students.

How to Sell by Tyler Bosmeny

Tyler Bosmeny

Startup School participants are urged to embrace founder-led sales by discarding the myth of the charismatic salesperson and leveraging their unique product passion to directly secure early adopters. Founders are advised to rigorously execute a funnel strategy targeting the 2.5% innovator market through personalized networking and cold outreach while avoiding costly customization traps. By maintaining a listening-heavy approach, pricing strategically based on validation rather than guesswork, and delaying sales hiring until they have personally closed deals, founders can effectively build a sustainable motion.

PR + Content for Growth by Kat Mañalac and Craig Cannon

Craig Cannon, Kat Manalac, Jeff, Gustav, Wade Foster, Paul Graham, Jessica, Robert, Trevor, Elon Musk, Joe Rogan, Ice-T, Mathilde, Harge, Laura Kolodny, Casey Neistat, Alex Jones, Kathleen Kingsbury

Founders are advised to prioritize product-market validation before launching content or press strategies, treating both as tools to drive specific engagement or conversion metrics rather than generic brand awareness. The framework emphasizes rigorous audience targeting and high-volume idea filtering for content production, while recommending that early-stage companies execute their own media relations by cultivating warm introductions and preparing data-backed, jargon-free pitches. Ultimately, success in these areas depends on measuring outcomes against defined goals like user acquisition or investor interest rather than relying on organic discovery or hiring expensive external agencies prematurely.

Sam Altman - How to Succeed with a Startup

Sam Altman

This analysis outlines how successful startups thrive by leveraging exponential market trends, achieving organic user growth through word-of-mouth, and relying on an evangelical founder to articulate a compelling vision. It emphasizes that victory requires teams balancing deep optimism with a bias toward action, allowing them to execute fast-changing ideas that large, slow-moving corporations cannot. Ultimately, survival depends on maintaining relentless momentum and building a defensible moat while capitalizing on the agility to pivot during major platform shifts.

Introduction to Incr_dom: Writing Dynamic Web Apps in OCaml

Cristina Rosu

Jane Street engineers presented IncurDOM, an internal OCaml web UI framework designed to handle high-frequency updates and datasets exceeding 10,000 rows while avoiding browser lag. The demonstration highlighted how incremental computations, partial rendering, and strict adherence to the Elm architecture enable efficient state management and automatic code sharing between server and client logic. Attendees examined practical trade-offs against React and BuckleScript, noting specific optimizations like `IncrMap` that reduce reconstruction costs while identifying future needs for explicit component abstractions and dedicated testing tools.

Opening Remarks and Keynote

Diane Helfrey, Michael Klowden, Dan Schnur, Toni Atkins, John Chiang

Hosted by the Milken Institute and Sacramento Bee director Dan Schnur, this conference convened key figures such as State Treasurer John Chung and Senate President Pro Tem Toni Atkins to launch a sustained dialogue on California's critical challenges in housing, workforce development, and climate finance. The event highlighted the urgent need for cross-sector collaboration to bridge the "missing middle" housing gap, address a projected 2030 labor shortage, and mobilize a record $1.75 billion JPMorgan Chase investment alongside a new state Green Bond Pledge. Attendees acknowledged a deep public trust deficit that can only be resolved by uniting public, private, and nonprofit leaders to implement innovative financing mechanisms and streamline legislative priorities for the state's future.

Mariya Nurislamova, Founder of Scentbird at the Female Founders Conference

Mariya Nurislamova, Maria

Sunbird successfully transformed from a failed recommendation algorithm into a subscription fragrance rental service after pivoting to a $15 monthly model inspired by Y Combinator's Michael Seibel. The company overcame early operational hurdles and significant fundraising rejections by leveraging a scarcity strategy to secure $150,000, eventually achieving acceptance into Y Combinator and raising a total of $25 million in capital. This strategic evolution enabled the team to scale operations to 250,000 users and expand internationally while adopting a high-performance hiring philosophy.

Jessica Livingston Shares 9 Things She Learned From Founding YC

Jessica Livingston

Founded in 2005 by Paul Graham and Jessica Livingston, Y Combinator revolutionized early-stage funding by implementing a batch model that supported over 1,800 startups through small equity stakes and an intentional "asshole-free" culture. Livingston, acting as the organization's social radar, prioritized founder dynamics and well-being over technical prowess, a strategy that facilitated unique successes like Reddit and Twitch while establishing a global network free from traditional investor pressure. Their complementary partnership, defined by Graham's technical vision and Livingston's focus on logistics and culture, created a resilient ecosystem that advises founders to pursue non-traditional paths rather than conforming to stereotypical success metrics.

The Results Are In: Predictive Technology and Your DNA Map

Christopher Mason

Led by geneticist Christopher Mason, a global team at the Milken Conference initiated a "metropoleome" project by collecting and sequencing phone swabs from 96 participants to map the genetic diversity and antimicrobial resistance of public surfaces. The resulting analysis of over 2,000 species and 560 resistance markers revealed that microbial profiles on mobile devices correlate strongly with lifestyle factors such as smoking, household size, and ancestry. With the full dataset of 1,000 samples scheduled for release within two weeks, the study establishes a vital global baseline for tracking antibiotic resistance genes and inferring dietary habits through mobile metagenomics.

Frank Luntz: Words That Work, 2018

Frank Luntz

Frank Luntz presented his "Words That Work 2018" framework at the Milken Institute, using real-time polling to demonstrate how James Comey's credibility collapsed due to factual errors while Stormy Daniels gained trust through specific narrative agency and personal autonomy. Luntz highlighted that extreme political polarization has eroded shared reality and eliminated ticket-splitters, creating a crisis where reputation is now strictly partisan and truth-telling cannot restore cross-aisle trust. The analysis concluded with strategic linguistic recommendations for leaders, such as adopting the "why-therefore-so" formula, replacing "diversity" with "inclusion," and prioritizing active listening to bridge the widening divide between Democrats and Republicans.

Can eco-tourism help save the ocean?

Marit Miner, Ahmad

In Indonesia's Coral Triangle, the Mizzul Marine Protected Area transitioned from a poached wasteland to a thriving ecosystem through a private-enterprise model founded by Andrew and Marit Miners. This initiative employs over 200 locals in conservation and tourism roles, utilizing ocean rangers to enforce a no-take ban that has boosted shark populations by 25 times and increased marine biomass by 600%. By generating revenue that exceeds former fishing income, the project demonstrates a scalable financial argument for biodiversity protection that local communities now control.

Announcing Work at a Startup

Jared Friedman, Matt Long, Craig Cannon

Scheduled for July, the Work at a Startup conference reunites Y Combinator partners Justin Kahn and Sam Altman with over 80% of the accelerator's hiring companies for a scaled event featuring 35 pitches across software, robotics, and deep tech. Attendees will engage directly with startups ranging from unicorns like Instacart to early-stage hardware firms offering roles in AI, DevOps, and co-founder positions, while also viewing live hardware demonstrations from entities such as Starsky Robotics. The gathering addresses critical market trends including remote work expansion, equity transparency, and the shifting definition of startup engineering to counter traditional compensation gaps.

A Conversation With Jane Goodall

Jane Goodall, Brian Sheth, Melissa Stevens

Jane Goodall and Brian Sheth discuss the convergence of private equity capital and global conservation through Goodall's Jane Goodall Institute and Sheth's leadership of Global Wildlife Conservation. They detail the expansion of Goodall's Roots & Shoots program to 150,000 youth groups and the institute's use of satellite technology to protect chimpanzee populations in Gombe and the Republic of Congo. The dialogue concludes with a strategic emphasis on integrating scientific rigor into policy-making and leveraging financial markets to sustain long-term environmental resilience.

When thoughts control machines

Brain-computer interface projects led by entities such as the U.S. Brain Initiative, Kernel, Neuralink, and DARPA are rapidly advancing from controlling prosthetics to decoding entire neural circuits with the goal of restoring motor function for paralyzed patients. As these technologies evolve to read and write neural codes, experts highlight critical ethical imperatives regarding neuroprivacy and the prevention of a societal capability gap between enhanced humans and artificial intelligence. The immediate focus remains on medical recovery, while long-term aspirations address the profound necessity of co-evolving with machines to ensure equitable access and safeguard human autonomy against the rapid pace of technological development.

OCaml All The Way Down

Andy Ray

This presentation outlines a hardware design framework utilizing the OCaml-based HardCAML domain-specific language to generate FPGA logic for custom peripherals like LED drivers, SPI sensors, and CORDIC math cores. The implementation targets the MicroBlaze soft CPU architecture, executing OCaml bytecode via a ZINC interpreter while leveraging standard Xilinx place-and-route tools to manage complex FPGA resources such as LUTs and DSP blocks. Future roadmaps prioritize full native CPU development within HardCAML, expanded formal verification using the Z3 solver, and the open-sourcing of testing infrastructure to reduce reliance on vendor-provided software components.