Latest Interviews

Wix Founder: Will Base44 Win the Vibe-Coding Wars? | The Truth About the Economics of Vibe-Coding

Avishai Abrahami, Harry Stebbings

Wix CEO Avishai Shalom defends the company's dual-platform strategy, which combines its $2.1 billion visual website builder with the $150 million ARR AI coding subsidiary Base44 to address market concerns over AI disruption. Despite a recent $80 million acquisition of a solo-founder engineering team and a $1.5 billion stock buyback, the company forecasts a hybrid future where Base44's headcount could double to 1,000 within two years to serve enterprise and custom needs. Shalom asserts that while AI will boost SMB efficiency in low-complexity tasks, the high trust and switching costs of Wix's established platform will continue to protect its core business from a complete market valuation collapse.

Andrew Feldman on Building a Chip 58x Larger Than Nvidia's

Andrew Feldman, Molly O'Shea

Cerebrus has secured a landmark partnership with OpenAI valued at over $20 billion to address the severe shortage of AI infrastructure caused by data center construction lagging behind compute demand. The company employs a co-design strategy to overhaul traditional power and cooling architectures while urging industry participants to diversify chip suppliers to avoid single-vendor lock-in. This surge in hardware innovation, marked by Cerebrus's recent IPO creating 1,000 millionaires, is expected to drive breakthroughs in cancer research, autonomous safety, and personalized education within the next quarter-century.

Sector Rotation Has Flipped the Script | At The Desk Ep.1

Ben, Phil

Capital is rotating out of speculative AI data center stocks into defensive sectors as the Federal Reserve signals potential rate hikes amid cooling inflation and a divergence between crypto assets and equities. Mega-cap tech firms like Nvidia and Broadcom saw share price declines despite record revenues due to guidance missing elevated expectations, while hyperscalers face scrutiny over massive capital expenditure projections and diminishing profit margins. Consequently, investors are shifting toward diversified long-short strategies and non-tech industries as concerns mount regarding the long-term unit economics of unprofitable AI enterprises.

What AI Leaders Really Think | Dylan Field, OpenAI, Boston Dynamics, MIT, IVP

Dylan Field, Ian Silber, Brian Ringley, Niko Klein, Holly Herndon, Zach Lieberman, Shreyas Garg, Molly

Figma's Dylan Field, Boston Dynamics' Brian Ringley, and OpenAI's Ian Silber outlined a strategic shift where AI serves as a collaborative lever for execution rather than a replacement for human intent, while advancing hardware reliability and interface fluidity. Speakers from IVP, MIT Media Lab, and musician Holly Herndon further emphasized that rapid prototyping, data curation, and systemic thinking are now essential for navigating the transition from static tools to autonomous agents in design and robotics. Collectively, the event framed the future of technology as a convergence of physical and digital realms that prioritizes high-level human creativity to overcome market homogenization and drive mass adoption of complex systems.

⁠Why OpenAI and Anthropic Won't Win the App Layer | Glean Founder

Arvind Jain, Harry Stebbings

Industry leaders project that enterprise AI will rapidly commoditize around open-source models, with Arvind Jain forecasting a three-year shift where most workloads run on such alternatives despite ongoing geopolitical concerns over Chinese capabilities. While organizations struggle to quantify ROI due to currently absurd token economics and inefficient inference costs, companies like Glean are betting on aggressive hiring and composite roles to build 10x superior products as the market matures. This strategy involves leveraging frontier model providers as assets rather than competitors, prioritizing specific problem-solving, and preparing for a rigorous audit of AI spending by 2026 to ensure genuine returns on investment.

OpenAI vs Anthropic IPOs, Anthropic $3T, Zuck's Price War, China Ends Open Source?, Trump Accounts

Zuck, Trump, Brad Gerstner, Friedberg, Chamath Palihapitiya

Markets are reacting to a wave of major AI initial public offerings, with SpaceX securing a $75 billion valuation and speculation mounting for Anthropic and OpenAI despite rising token costs and plateauing productivity gains. Geopolitical tensions are intensifying as nations build sovereign infrastructure to counter US dominance, while energy constraints loom as the primary bottleneck for global AI expansion. Domestically, the "Invest America" Act has mobilized bipartisan support by launching tax-advantaged "Trump Accounts" that aim to create $1 to $4 trillion in wealth for millions of children through automated S&P 500 investments.

Why the US Dollar Could Continue to Strengthen

Brian Dunne, Chris Hussey

Driven by geopolitical tensions with Iran, robust U.S. corporate performance, and a shifting Federal Reserve stance toward rate hikes, analysts project sustained dollar strength against global rivals. This outlook supports a primary strategy of long USD positions against G10 currencies, particularly the Swiss Franc, to capitalize on favorable interest rate differentials and potential central bank divergence. Market participants also anticipate upside in specific emerging markets like Brazil and Egypt while noting that structural challenges to the dollar's reserve status remain distant.

General relativity from first principles – Adam Brown

Adam Brown, Einstein, Jed Thompson, Dwarkesh

Building on Albert Einstein's century-long effort to resolve the incompatibility between Newtonian gravity and the speed of light, General Relativity redefines gravitation as the geometric curvature of spacetime caused by mass and energy. This theoretical framework predicts phenomena such as black holes, gravitational time dilation, and light bending, all of which have since been empirically validated through solar eclipse observations, stellar orbit tracking, gravitational wave detection, and direct event horizon imaging. While the theory remains a triumph of mathematical deduction, modern researchers are exploring how artificial intelligence might further assist in uncovering unified physical laws by navigating complex solution spaces where experimental data is currently scarce.

Kalshi's Co-CEOs Disagree by Design — Why Constant Conflict Became Their Pattern

The event details a leadership model within a complex organization where intentional, continuous disagreement serves as a core operating pattern to balance regulatory risk against innovation. This approach relies on designated contrarian voices that act as a necessary check by identifying potential failure points when team enthusiasm peaks. Ultimately, the strategy establishes a delicate, constant mechanism for navigating the tension between advancing new initiatives and adhering to strict regulatory constraints.

YC's Head of Design Shows You How To Design With AI

Eve Bouffard, Aaron Epstein, Ev Bufar

Designer Ev Bufar utilizes a voice-first workflow with tools like Aqua, Conductor, and Paper.design to rapidly produce high-fidelity assets for diverse projects, including the Paxyl transcript analyzer and the Soda Zine. Her recent work at Startup School demonstrates an agent-driven production model that generated visual identities for 6,000 attendees through custom shaders and automated speaker assets, while Paxyl analyzes coding agent interactions to reveal developer patterns. By prioritizing massive context density and disposable internal models, Bufar accelerates the design iteration cycle to handle complex branding and interactive web experiences that explicitly cater to both human users and AI agents.

"Dig Through Your Couches. SpaceX Needs It." Cyan Banister on Luke Nosek's Pitch

Cyan Banister, Luke Nosek, Scott Banister, Molly O'Shea

Ranking as the world's top angel investors, Cyan and Scott Bannister leverage a methodology of identifying non-obvious trends to secure transformative stakes in companies like SpaceX and Anduril. During their discussion at Long Journey HQ, they outline a future dominated by AI-driven robotics while advocating for decentralized models to counter surveillance states and urging a shift away from traditional degrees toward artisanal entrepreneurship. Blending this strategic foresight with personal philosophies on radical authenticity and introspection, the couple emphasizes the critical need for American deep tech resurgence to navigate the coming "consumer wave" of artificial intelligence.

Open Source Wins, AGI Is Here, and Scorsese’s AI Toolkit with CEOs of Cerebras & Black Forest Labs

Andrew Feldman, Robin Rombach, Martin Scorsese

Cerebras Systems leverages a $25 billion order backlog from major tech giants to deploy chips that accelerate AI reasoning fifteen times faster than standard inference, effectively achieving early Artificial General Intelligence while reshaping global energy infrastructure. Simultaneously, Black Forest Labs utilizes its pioneering latent diffusion algorithms to bridge generative media and robotics, partnering with entities like Martin Scorsese to create scalable production tools and autonomous "world models." Both companies advocate for a hybrid ecosystem combining open-source accessibility with proprietary sovereignty, aiming to resolve economic bottlenecks and regulatory challenges through staged deployments and secure data practices.

The Next Era of Health | Global Conference 2026

Esther Krofah, Robert Bradway, Nancy Brown, Alicia Jackson, Myechia Minter-Jordan, Dipen Parekh

Addressing a critical demographic tipping point and a $1 trillion caregiver gap, stakeholders including AARP, ARPA-H, and the American Heart Association are reforming U.S. healthcare to bridge the divide between technological innovation and clinical delivery. Initiatives range from deploying agentic AI to extend cardiovascular prevention to counties lacking specialists, to accelerating long-term care research through new regulatory pathways and a target reduction of drug discovery timelines to under five years. Concurrently, global competition drives a strategic pivot toward genomic integration and value-based models, with specific commitments to reduce Lipoprotein(a) levels by 95% and establish federal tax credits for the nation's 63 million caregivers.

Every Startup Has a Hole in the Ship — Kalshi's Tarek Mansour on the Problem You Can't Delegate

Tarek Mansour

The speaker distinguishes between organizations that actively confront critical internal flaws and those that ignore them, asserting that unaddressed defects inevitably lead to failure despite external growth. In January, the industry identified a reputational leak caused by public confusion between regulated platforms like Calci and unregulated offshore operators such as Polymarket. To resolve this, the organization has initiated a strategy to educate stakeholders on the necessity of regulation, aiming to normalize compliant operations and distinguish them from non-compliant models.

Enterprises Fear Frontier Models | Sam Altman Offers Trump 5% of OpenAI | DeepSeek Builds Own Chips

Sam Altman, Trump, Jason Lemkin, Rory O'Driscoll, Harry Stebbings

OpenAI and the U.S. government are exploring regulatory frameworks involving pre-approval processes and potential equity stakes, while major tech firms like Meta and SpaceX pivot toward selling excess compute infrastructure to reshape market dynamics. In the enterprise sector, adoption bottlenecks arising from talent shortages are slowing diffusion rates despite aggressive service deployment strategies by Microsoft and Amazon. Concurrently, venture capital is normalizing high-dilution financing and secondary liquidity events as geopolitical tensions accelerate a bifurcation between U.S. closed-source models and China's advancing open-source alternatives.