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  1. RAISE Summit18 min

    Eric Piscini (Hashgraph) & Jonathan Dotan (EQTY Lab): Proof of Trust Rethinking AI ft. DLTBlockchain

    Eric Piscini, Jonathan Dotan

    Equity Lab and its partner Hedera are deploying a hardware-rooted system that leverages next-generation Intel and NVIDIA secure enclaves to generate tamper-proof certificates for AI agents, addressing the critical trust barrier identified by business leaders. This architecture delivers a 400,000x performance improvement in cryptographic proof generation while recording immutable audit trails on the Hedera blockchain to ensure compliance with global regulations like GDPR. Following a successful pilot with 11 Accenture agents, the technology positions itself as an essential infrastructure for the projected trillions of autonomous agents expected to dominate future web traffic and enterprise supply chains.

  2. RAISE Summit34 min

    Ori, PolyAI, Cresta, Writer & Fireworks AI: Is Enterprise Defensibility Possible in an AI's World?

    Mike Butcher, May Habib, Russell Banzon, Nicola, Lynn, Amalia, Mahdi

    Industry leaders convened to declare that traditional SaaS and seat-based pricing models are collapsing as enterprises pivot to agentic AI, where value is derived from direct outcomes and autonomous revenue generation rather than software access. The consensus emphasizes that architectural advantages are temporary, with true defensibility emerging only through proprietary data flywheels and comprehensive organizational adoption strategies that integrate AI into core workflows. Looking toward 2025, the panel predicts a surge in production-level deployments driven by a tenfold reduction in infrastructure costs, forcing companies to prioritize offensive scaling over defensive postures to survive rapid market disruption.

  3. RAISE Summit29 min

    Anjney Midha of a16z: Algorithmic Independence The Next Frontier in National Infrastructure

    Anjney Midha

    The event defines Sovereign AI as a four-tiered strategy for achieving technical and cultural independence, utilizing methods like mid-training to correct deep-seated biases rather than simple fine-tuning. As nations transition from closed-source prototypes to open-source models, a geopolitical divide is emerging where "hypercenters" like the US and China face competition from Europe's "Mistral Compute" initiative while non-hypercent nations adopt joint-venture models to retain value. The discussion concludes with predictions that general-purpose robotics and universal computer use will mature within two years, leveraging Europe's specific strengths in computer vision to secure its strategic position in the global AI landscape.

  4. RAISE Summit35 min

    AI Visionaries Panel: Collaboration is All You Need! Open Source as AI's Great Accelerator

    Olivier, Ankit, Matt, Mitchell, Jim, Jonathan

    Leaders from Nvidia, Red Hat, Mozilla, and the Linux Foundation convened to analyze the symbiotic relationship between AI-driven investment strategies and the accelerating open-source ecosystem. The panel emphasized that while artificial intelligence boosts code velocity, the primary value in commercial open source now lies in community coordination and neutral standards that prevent market fragmentation. Key outcomes included the identification of a "reverse venture capital" approach for selecting durable projects and a consensus that human oversight remains critical for navigating the legal and architectural challenges of AGI development.

  5. RAISE Summit18 min

    Aurélien Rodriguez, Director at Cohere: Building AI for Security-Minded Enterprises

    Aurélien Rodriguez

    In this session, a former Meta AI researcher now directing foundation model training at Cohere explains how the company prioritizes secure, grounded generation over pursuing Artificial General Intelligence. The discussion highlights a strategic shift toward on-premise deployment and retrieval-augmented pipelines that ensure data remains within client environments while minimizing hallucinations through strict source verification. By leveraging co-development partnerships with entities like Fujitsu and RBC, the organization focuses on specialized, high-value tools that deliver concrete business impact in regulated sectors without mimicking human biology.

  6. RAISE Summit34 min

    Bruno Gagliardo, Global Head of Data & AI @ Sanofi : Molecule to Market, Driving AI Transformation

    Bruno Gagliardo, Larry Orimoloe

    Sanofi CEO Bruno Gagliardo unveiled a five-year strategy to transform the pharmaceutical giant into a "pharma tech" leader by migrating 85,000 employees to a cloud-based data mesh architecture powered by large-scale AI. The initiative integrates the RAISE governance framework and a $100 million impact barrier to mitigate hallucination risks while accelerating drug discovery and regulatory submissions from 19 weeks down to five. This cultural shift prioritizes AI augmentation over replacement, utilizing agentic systems and a hybrid build-or-buy approach to deliver substantial efficiency gains across research, manufacturing, and commercial operations.

  7. All-In Podcast27 min

    Alibaba's Joe Tsai on US-China Rivalry, AI Future, Owning the Nets/Liberty, Caitlin Clark's Impact

    Joe Tsai, Caitlin Clark, Chamath, Jason, Friedberg

    Business leader Joe Satt outlines Alibaba's strategic pivot toward AI-driven efficiency, highlighting a 14.5% stock surge following the Qwen 2.5 Max launch and a corporate culture where 30% of engineering code is now AI-generated. He contrasts U.S. and Chinese market dynamics by discussing the WNBA's surge in popularity driven by Caitlin Clark while arguing that U.S.-China relations represent necessary economic competition rather than bitter rivalry, noting China's 50% corporate AI adoption rate. Satt further critiques structural differences in American versus Chinese education and governance, asserting that the future of technological progress relies on cooperation in fields like medicine rather than a zero-sum race for dominance.

  8. RAISE Summit22 min

    WEKA, Cohere, Nebius: Rewriting the Rules Agentic AI and the Race to Scale

    Lauren Vaccarello, Cécile Robert-Michon, Dan Shtan, VYACHESLAV TYKHONOVSKYI, DAN GALPIN, Danila

    At a panel on AI infrastructure and economics, Weka CMO Lauren Vaccarello, Cohere's Cécile Robert-Michon, and Nabeus CTO Dan Galpin discussed the necessity of rethinking legacy systems to support massive scale and agentic AI. The speakers emphasized that modern requirements prioritize intelligence per token over raw cost efficiency, citing Nabeus's software-first approach that achieves near-NVIDIA benchmark performance without virtualization and Cohere's converged storage solutions that deliver 20x faster checkpointing. They concluded that enterprises must abandon rigid long-term planning in favor of short-cycle agility to navigate the rapidly shifting demands of privacy, security, and compute resources in a commercial AI landscape.

  9. Milken Institute36 min

    Influence to Shape Platforms for Good | Asia Summit 2025

    Ross Butler, Bhumi Pednekar, Curtis S. Chin

    Actors Bhumi Pednekar and Ross Butler discuss their respective careers of dismantling stereotypes in Indian and Hollywood cinema while highlighting the societal pressures to pursue traditional professions over creative arts. Beyond entertainment, both advocates emphasize the transformative power of social media for disaster relief and mental health awareness, with Pednekar leading UNDP climate initiatives and Butler championing cross-cultural co-productions in Southeast Asia. Looking forward, the duo plans to collaborate on a project bridging Indian and Asian narratives while mentoring emerging talent to redefine regional storytelling globally.

  10. Goldman Sachs44 min

    Memorial Sloan Kettering Cancer Center’s CEO on the Future of Cancer Treatment

    Selwyn M. Vickers, Brian Robinson, Dr. Selwyn Vickers

    Memorial Sloan Kettering leverages its vast biobank and dual expertise in computational oncology to drive a "golden era" of cancer treatment, where AI-driven predictive models and breakthroughs in immunotherapy have transformed survival rates for aggressive malignancies. Concurrently, the institution confronts rising youth cancer incidence and systemic health inequities by developing accessible genetic screening tools and deploying low-infrastructure immunotherapy protocols globally. These clinical and technological advances are grounded in a leadership philosophy that prioritizes professional excellence to dismantle socioeconomic barriers and improve care access for underserved populations.

  11. a16z56 min

    Opendoor CEO: Building the Amazon for Homes

    Kaz Nejatian, Alex Rampell, Erik Torenberg

    CEO Kaz Nejatian is steering Opendoor away from its failed inventory-heavy iBuyer model toward a software marketplace aiming to control 10% of housing supply to disrupt traditional agent monopolies through 1% commissions. Following a strategic pivot triggered by the "triple whammy" of Zillow's competition, rising interest rates, and capital pullback, the company now operates in every U.S. market with features like Dallas' seven-day return window to build high-frequency demand. The ultimate vision is to internalize the entire real estate transaction chain by bundling financing and insurance, thereby reducing friction and delivering net value to consumers while avoiding the pitfalls of operating as a low-frequency asset-holding business.

  12. Y Combinator41 min

    Ask These Questions Before Starting An AI Startup

    Jordan Fisher

    Founder and alignment researcher Sam Altman warns that the imminent arrival of AGI within two to three years forces startups to radically rethink hiring, product design, and long-term strategy beyond traditional focus models. He argues that enterprises will soon bypass external SaaS providers by building internal software with AI, while consumer markets may shift from static apps to on-demand, AI-generated solutions that require new trust mechanisms like automated auditing. Ultimately, Altman urges founders to prioritize solving hard infrastructure problems and societal impact over immediate monetization, as the window to build defensible moats against commoditization and centralized control narrows rapidly.

  13. All-In Podcast12 min

    The Next Bubble Is Already Here - Chamath Palihapitiya

    Chamath Palihapitiya, Jason, Friedberg, Nick

    Speakers warn that the private equity sector, having grown to $5 trillion through artificial borrowing, faces a structural collapse driven by mismanagement and stagnant distributions as capital migrates toward a new bubble in private credit. To address the dysfunction of traditional IPOs and flawed SPAC structures, the Raptor 2 initiative has secured backing from 98.7% of blue-chip institutional investors to introduce a transparent, performance-aligned model for high-growth companies. Future iterations, Raptor 3, propose a "pre-baked IPO" using pure common stock to eliminate conversion risk and ensure fair pricing for public shareholders.

  14. a16z1h 3m

    The Lawyerly Society vs. The Engineering State: Who Owns the Future?

    Dan Wang, Steven

    Dan Filgate frames the U.S.-China competition not as a race with a definitive winner, but as a complex synthesis where American strengths in wealth creation and intellectual property must balance against China's engineering-driven capacity for infrastructure and manufacturing. The analysis highlights critical frictions between the U.S. "lawyer culture," which often paralyzes industrial progress through legal hurdles, and China's ability to enforce large-scale goals despite systemic human rights concerns and IP vulnerabilities. Ultimately, the dialogue urges the United States to avoid complacency by adopting more functional industrial policies that prioritize physical production and logistical efficiency rather than rigid legalistic processes.

  15. Sourcery with Molly O'Shea51 min

    Joby, Dirac & Allen Control: The Future of Air, AI Factories & Defense Tech

    Molly O'Shea, Eric Allison, Filip Aronshtein, Steve Simoni

    The Reindustrialize 2024 summit in Detroit highlighted strategic capital infusions and operational expansions by key players such as Joby Aviation, Dirac, and Allen Control Systems to address critical gaps in the American industrial base. Joby Aviation secured further funding and strategic partnerships to advance its FAA-certified eVTOL air taxi program, while Dirac deployed AI-driven software to automate manufacturing instructions and preserve tribal knowledge, and Allen Control Systems raised capital to scale its "Bullfrog" kinetic defense turret for drone warfare. Collectively, these developments reflect a broader industry urgency to reverse offshoring trends, reintegrate vertically controlled supply chains, and deploy domestic manufacturing solutions amidst evolving geopolitical and technological pressures.