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  1. All-In Podcast1h 30m

    Can the AI Industry Regulate Itself? Stripe Wants PayPal, China Catches Up, NY Bans Datacenters

    Demis Hassabis, Mira Murati, Jason Calacanis, Chamath Palihapitita

    DeepMind's Demis Hassabis and major industry leaders are advancing a US-led self-regulatory organization for AI that prioritizes independent expert oversight over government agencies to prevent global developmental stagnation. While this framework aims to manage catastrophic risks through voluntary-to-mandatory adoption, skepticism remains regarding potential regulatory capture by major labs and competing strategies to impose stricter federal certifications. Concurrently, the sector faces disruptive financial and legal dynamics, including a proposed Stripe-PayPal-Block merger and a high-profile trade secret lawsuit between Apple and OpenAI, as the industry navigates severe energy constraints and a widening cost gap between enterprise and frontier models.

  2. All-In Podcast1h 20m

    Iran War, Oil Shock, Off Ramps, AI's Revenue Explosion and PR Nightmare

    Brad Gerstner, Howard Schultz, Jason Calacanis, David Sacks

    The discussion centers on a dual strategy of domestic wealth redistribution through direct child equity accounts and geopolitical risk management during a volatile conflict in the Middle East that spiked oil prices and inflation. Industry leaders debate the scalability of AI revenue, contrasting production-ready utility against experimental testing, while simultaneously analyzing how "doomerism" narratives and restrictive regulations threaten data center development and profitability. Finally, the program examines the economic consequences of state-level wealth taxes on migration patterns, warning of capital flight and budget shortfalls while advocating for deregulation as a superior alternative to asset seizure.

  3. All-In Podcast1h 21m

    Software Stocks Implode, Claude's Hit List, State of the Union Reactions, Trump's Tariff Pivot

    Trump, Friedberg, Jason Calacanis, Chamath Palihapitiya, David Sacks

    The event analyzes a dramatic market shift where Anthropic's AI announcements triggered significant stock declines across legal, security, and computing sectors, signaling a transition from debating AI's timeline to questioning the survival of current business models. Concurrently, the discussion contrasts this volatility with a labor paradox where rising AI tool costs drive higher engineering demand, while highlighting structural constraints in energy infrastructure and a Supreme Court ruling that temporarily stalled executive tariff powers. The session concludes by examining breakthrough medical trials for aging reversal and noting a political climate where legislative polarization has deepened despite moments of rare bipartisan agreement.

  4. All-In Podcast1h 13m

    Debt Spiral or NEW Golden Age? Super Bowl Insider Trading, Booming Token Budgets, Ferrari's New EV

    Friedberg, Chamath Palihapiti, Jason Calacanis

    Scheduled for May 31 through June 3 in Wine Country, the "Liquidity" retreat will convene a select group of capital allocators and technology CEOs to facilitate transparent deal-making and network expansion. This exclusive event targets emerging and established leaders in public and private markets to foster direct capital allocation opportunities outside traditional closed-door channels. Attendees must undergo a rigorous application process to ensure the gathering includes a diverse mix of top-tier managers and innovators focused on navigating current economic and technological shifts.

  5. All-In Podcast1h 31m

    All-In's 2026 Predictions

    Chamath, Jason Calacanis, David Friedberg, David Sacks

    A group of prominent tech investors and founders, including David Sacks, Jason Calacanis, Chamath Palihapiti, and David Friedberg, discussed their 2026 economic, political, and business forecasts following Sacks' relocation to Austin amid concerns over California's proposed wealth tax. The panel projects a 4.5% to 6% U.S. GDP growth driven by the "Trump Boom" and productivity surges while predicting significant market disruptions such as the collapse of traditional SaaS models and a surge in IPOs for private giants like SpaceX and Stripe. Additionally, the conversation addressed emerging trends in deal-making and media, with participants anticipating a shift toward IP licensing agreements, the rise of citizen journalism, and potential geopolitical resolutions in Ukraine and Iran.

  6. All-In Podcast1h 7m

    Inside the White House Tech Dinner, Weak Jobs Report, Tariffs Court Challenge, Google Wins Antitrust

    Chamath, Friedberg, Jason Calacanis, David Sacks

    President Trump convened a dinner with thirty global tech leaders, including Tim Cook, Sam Altman, and Bill Gates, to discuss regulatory alignment and the pro-innovation agenda under his administration. Simultaneously, legal and economic developments shaped the business landscape, as a federal appeals court challenged the administration's tariff authority while a Google antitrust ruling acknowledged the company's monopoly status but rejected structural breakup due to emerging AI competition. The gathering concluded with private Oval Office tours and a chaotic press briefing, reinforcing the administration's focus on infrastructure, tax reform, and shifting market dynamics driven by artificial intelligence.

  7. All-In Podcast1h 51m

    OpenAI's GPT-5 Flop, AI's Unlimited Market, China's Big Advantage, Rise in Socialism, Housing Crisis

    Gavin Baker, Ben Shapiro, Phil Deutch, Jason Calacanis, David Sacks, Friedberg

    Co-hosts Jason Calacanis and David Sacks led a full roster of guests, including Ben Shapiro and Gavin Baker, in a discussion spanning OpenAI's GPT-5 release, China's energy expansion, and U.S. tariff revenue trends that have hit $127 billion in early 2025. The panel analyzed the economic implications of artificial intelligence, with debates centering on whether productivity gains will materialize as rapidly as infrastructure investments while addressing geopolitical risks like Nvidia GPU smuggling and state-sponsored capitalism. Additionally, the hosts critiqued Apple's innovation stagnation, examined the "imperial presidency" versus administrative overreach, and concluded with a diverse lineup of summer book and television recommendations from the featured experts.

  8. All-In Podcast2h 2m

    The Great Tariff Debate with David Sacks, Larry Summers, and Ezra Klein

    David Sacks, Larry Summers, Ezra Klein, Friedberg, Jason Calacanis, Chamath Palihapitiya

    On the eighty-day mark of President Trump's second term, the administration paused reciprocal tariffs to force global negotiations while enforcing a 125% hike on China, triggering historic market volatility and a cumulative $6 trillion loss since "Liberation Day." Critics like Larry Summers and Ezra Klein warn that this erratic "Peron-style" governance and the DOGE initiative's aggressive austerity measures risk destroying essential state capacity and triggering a deep recession, while proponents such as David Sacks and Chamath Palihapitiya defend the chaotic strategy as necessary game theory to secure onshoring of critical technologies and reset trade frameworks.

  9. All-In Podcast1h 37m

    DOGE vs USAID, Crypto Framework, Google's $75B AI Spend, US Sovereign Wealth Fund, GLP-1s

    Antonio Gracias, Sacks, Chamath, Friedberg, Jason Calacanis

    David Sacks and Antonio Gracias lead the Department of Government Efficiency in auditing USAID for potential fraud and waste while simultaneously pushing for a US Sovereign Wealth Fund to monetize government assets like TikTok stakes and federal land to reduce the national debt. The administration further advances a crypto regulatory framework prioritizing stablecoin legislation and proposes a tax plan eliminating levies on tips, overtime, and Social Security benefits for seniors. Amidst these policy shifts, market participants analyze Google's record-breaking earnings and $75 billion AI infrastructure investment, while medical experts review new VA data suggesting GLP-1 drugs offer significant cardiovascular and neurological benefits beyond weight loss.

  10. All-In Podcast1h 36m

    "Founder Mode," DOJ alleges Russian podcast op, Kamala flips proposals, Tech loses Section 230?

    Kamala, Ryan Breslow, Chamath Palihapitiya, David Sacks, Jason Calacanis, David Friedberg

    The All-In Summit convenes a diverse roster of high-profile figures including Elon Musk, Peter Thiel, and Senator Kirsten Sinema to dissect critical industry shifts, ranging from Y Combinator's "Founder Mode" debate to a landmark court ruling redefining algorithmic liability under Section 230. The event features a strategic Google Cloud partnership offering $350,000 in credits to eligible AI founders and addresses polarizing geopolitical topics such as Russian media interference via Tenet Media and Kamala Harris's recent economic policy pivots. By examining these disparate themes alongside discussions on Bolt's valuation volatility and professional management evolution, the summit establishes a comprehensive platform for analyzing the intersection of technology, regulation, and global power dynamics.

  11. All-In Podcast1h 26m

    Biden chaos, Soft landing secured? AI sentiment turns bearish, French elections

    Friedberg, Jason Calacanis, Chamath Palihapitiya, David Sacks

    The event analyzed conflicting economic signals where June's 3.0% CPI print and 4.1% unemployment rate have shifted market expectations toward an 89% probability of a Federal Reserve rate cut by September. Panelists debated the sustainability of the AI sector, with Goldman Sachs and Sequia Capital projecting massive capital expenditure gaps against limited near-term productivity gains, while also examining rising geopolitical instability in France and accelerating concerns regarding President Biden's cognitive fitness that may force a Democratic succession. Additionally, the discussion highlighted personal developments including Jason Calacanis's appointment to Fox News and the "All-In" podcast's market dominance ahead of the September summit in Los Angeles.

  12. All-In Podcast1h 48m

    Trump verdict, COVID Cover-up, Crypto Corner, Salesforce drops 20%, AI correction?

    Trump, Chamath, Jason Calacanis, David Sacks

    In a New York courtroom, a jury convicted Donald Trump of 34 felony counts related to falsified business records, prompting predictions from experts like David Sacks and Jason Calacanis that the verdict will serve as a fundraising catalyst and potentially lead to a gubernatorial pardon. Concurrently, investigators uncovered evidence that the NIH funded gain-of-function research at the Wuhan Institute of Virology, leading the panel to accuse the agency and Anthony Fauci of a systematic cover-up regarding the pandemic's origins. The discussion further analyzed the political impact of Bitcoin's recent halving, noting that crypto advocacy could sway millions of votes, while also highlighting a major market correction in the SaaS sector driven by AI disruption and slowing revenue growth.

  13. All-In Podcast1h 41m

    GPT-4o launches, Glue demo, Ohalo breakthrough, Druck's Argentina bet, did Google kill Perplexity?

    Phil Hellmuth, Friedberg, Stanley Druckenmiller, Javier Milei, Chamath Palihapitiya, David Sacks, Jason Calacanis

    Hosts Chamath Palihapitiya, Jason Calacanis, David Sacks, and Freddie Friedberg discuss the launch of OpenAI's GPT-4o, Google's AI Overviews, and Sacks' agricultural breakthrough Ohalo Genetics, which uses boosted breeding to double crop yields. The episode further details significant investment updates, including $2 million raised for Ohalo, Calacanis's stake in AI training service Athena Wow, and Stanley Druckenmiller's pivot to the Argentine market following Javier Milei's election. Throughout the conversation, the group analyzes macroeconomic trends in the US and Argentina while predicting that basic AI capabilities will become standard infrastructure, fundamentally reshaping enterprise software and agricultural productivity within two years.

  14. All-In Podcast1h 43m

    Sam Altman: Getting Fired (and Re-Hired) by OpenAI, Agents, AI Copyright issues

    Sam Altman, Chamath, Friedberg, Jason Calacanis, David Sacks

    Sam Altman outlined OpenAI's strategy to prioritize widespread accessibility of advanced AI and international safety governance while navigating hardware constraints and evolving intellectual property frameworks. The discussion detailed a shift toward specialized model architectures for scientific discovery, the complexities of the November 2023 leadership transition, and speculation on new hardware partnerships with Apple. Ultimately, the event emphasized a vision where artificial general intelligence transforms healthcare and scientific research through rapid, low-cost computation and rigorous global oversight.

  15. All-In Podcast1h 15m

    Sheryl Sandberg, plus open-source AI gene editing explained

    Sheryl Sandberg, Dave Goldberg, Chamath, Friedberg, TheZachEffect, Jason Calacanis, David Sacks

    Hosts Chamath Palihapitiya, Jason Calacanis, and David Sacks interview Sheryl Sandberg about her documentary *Screams Before Silence*, which utilizes survivor testimony to combat denialism regarding sexual violence committed by Hamas on October 7th while critiquing the silence of feminist organizations and university policies. The conversation also pivots to Profluent Bio's open-sourced AI-designed gene editing tool, Open CRISPR-1, which the hosts argue could democratize biotechnology by bypassing restrictive intellectual property landscapes and accelerating innovation in life sciences. Throughout the episode, the hosts balance a tribute to the late Dave Goldberg with substantive debates on war crimes documentation and the economic potential of open-source biological models.