Latest Interviews
Showing 211–225 of 2,499 transcripts.
Clear all filters- The Economist8 min
Are AI models running out of power? | The Economist
Facing severe hardware shortages and monopoly choke points where Nvidia and TSMC dominate supply, major AI developers like OpenAI and Anthropic are throttling services and redirecting resources to manage capacity. In response to these constraints, five cloud providers plan a $700 billion infrastructure build-out while companies grapple with three-to-five-year lead times for essential components and aging chip inventories. This fundamental mismatch between rapid software cycles and slow physical production is projected to reverse declining inference costs, potentially raising prices and slowing overall industry adoption.
- All-In Podcast1h 21m
OpenAI Misses Targets, Codex vs Claude, Elon vs Sam Trial, Big Hyperscaler Beats, Peptide Craze
Elon, Sam, Friedberg, Jason Calacanis, David Sacks, Chamath Palihapitiya
OpenAI faces mounting structural tensions as it misses 2025 revenue and user targets while CEO Sam Altman pushes for an IPO against CFO Sarah Fryer's caution amidst $600 billion in future compute commitments. The company currently maintains a compute advantage over rivals like Anthropic through excess data center capacity, even as the broader AI sector grapples with power grid bottlenecks and a record $725 billion in hyperscaler capital expenditures for 2026. Concurrently, Elon Musk pursues a $150 billion lawsuit alleging a breach of charitable trust following internal documents revealing plans to remove him before the entity's conversion to for-profit status.
The $10 Trillion Bet on Humanoid Robots | Figure Founder Brett Adcock
Founded by Archer eVTOL creator Brett Adcock, Figure AI pursues the commercialization of general-purpose humanoid robots capable of operating autonomously for extended shifts across diverse industries. Having raised nearly $2 billion with a $39 billion valuation, the company recently terminated an OpenAI partnership to maintain control over its vertically integrated hardware and AI stack, aiming to triple production by May and deploy thousands of units within the year. Despite facing technical hurdles in scaling reliability, Figure projects a market opportunity worth trillions as it transitions from prototype testing to mass commercial deployment in homes and factories.
- Y Combinator41 min
Demis Hassabis: Agents, AGI & The Next Big Scientific Breakthrough
DeepMind CEO Demis Hassabis projects Artificial General Intelligence will emerge around 2030, contingent on inventing specific architectural breakthroughs in continual learning and structured memory rather than merely scaling current methods. While deep tech startups are warned to anticipate AGI disrupting their decade-long cycles, the organization is simultaneously deploying efficient, modular "Flash" and open-source nano models to power edge devices and accelerate scientific discovery in fields like drug design and materials science. Ultimately, DeepMind advocates for interdisciplinary collaboration between AI and physical sciences to overcome current reasoning limitations and drive the next generation of autonomous agents.
300 Pages on Anduril: Inside Modern Warfare
Anduril Industries disrupts the defense sector by replacing the Pentagon's cost-plus acquisition model with fixed-cost contracts and a "build-to-mission" strategy that prioritizes high-volume, low-cost autonomous systems. The company utilizes its proprietary Lattice AI platform to integrate multi-domain assets into a unified network, aiming to counter China's industrial superiority by accelerating the production of drones, torpedoes, and munitions. Founded on the philosophy that credible military capability is essential for conflict deterrence, Anduril has seen its valuation double to roughly $60 billion as global power dynamics shift toward Great Power competition.
- Milken Institute20 min
A Conversation with IMF Managing Director Kristalina Georgieva | Global Conference 2025
Kristalina Georgieva, Gerard Baker
Following an IMF downgrade of the global growth forecast to 2.8%, Managing Director Kristalina Georgieva addresses diverging inflation trajectories and rising fiscal constraints while urging China to undertake structural reforms to shift toward domestic consumption and reduced state intervention. Amidst a volatile trade landscape marked by the erosion of fair trade mechanisms and a transition to new economic equilibriums, policymakers are prioritizing bilateral agreements and supply-side productivity enhancements to stabilize financial markets and foster sustainable expansion. This strategic pivot seeks to navigate "off the charts" uncertainty by balancing emerging market resilience against the severe deflationary pressures in China and the debt challenges facing advanced economies.
- a16z58 min
Aaron Levie on AI Adoption and Enterprise Workflows | The a16z Show
Aaron Levie, Steven Sinofsky, Martin Casado
Organizations are pivoting from failed centralized AI mandates to integrating autonomous agents directly into legacy workflows, necessitating significant architectural shifts beyond traditional hybrid software models. While token-gaming and system integration bottlenecks currently stifle productivity gains, the resulting increase in infrastructure complexity and code volume is projected to drive sustained demand for engineering talent rather than reduce it. This transition requires years of organizational change management to modernize fragmented data environments, ultimately creating a multi-decade opportunity for system integrators to bridge the gap between probabilistic machine users and rigid enterprise security protocols.
- Goldman Sachs18 min
Winning the Right to Invest: 20VC’s Harry Stebbings
Harry Cassell reframes media distribution as a critical weapon for securing investment rights, leveraging a data-driven content strategy that generated $6.1 million in 36 hours to differentiate his platform from traditional venture capital models. Critiquing the current market's saturation by large multi-stage funds, he emphasizes founder empathy, specific personality traits, and a robust LP network to navigate an environment where capital is commoditized and growth expectations have shifted. Looking toward Europe, Cassell predicts a decade of massive company creation driven by lower barriers to entry and increased founder resilience, citing early successes like Lovable as evidence of a reinvigorated ecosystem ready to compete globally.
- Y Combinator39 min
Replit's CEO On The Only Two Jobs Left In The Company Of The Future
Replit recently secured $400 million in Series D funding to achieve a $9 billion valuation while executing a strategic pivot toward "AI-native developers" who build software through natural language interactions with their Agent 4 system. By abstracting traditional coding behind multimodal AI agents, the platform enables non-engineers to rapidly deploy applications and reduce development costs by up to 70%, effectively shifting the company's focus from technical setup to high-level business orchestration. This product-led growth model empowers a diverse range of users, from solo entrepreneurs to enterprise teams, to accelerate idea velocity and build internal tools without requiring deep programming expertise or large engineering budgets.
- All-In Podcast1h 31m
SpaceX-Cursor Deal, SaaS Debt Bomb, New Apple CEO, SPLC Indictment, Colon Cancer Spike
John Ternus, Tim Cook, David Sacks, David Freiberg
David Sacks reported to the White House that President Trump is actively supporting AI development and private power generation, while SpaceX finalized a definitive agreement to acquire Cursor for up to $60 billion to leverage its GPU infrastructure against competitors. Simultaneously, the discussion highlighted severe distress in the SaaS sector driven by AI disruption and a major fraud indictment against the Southern Poverty Law Center involving hidden accounts and payments to hate groups. In health news, a Barcelona study identified the herbicide piclorum as a significant environmental trigger for a sharp rise in colorectal cancer among young adults, prompting calls for updated safety testing and regulation.
- Y Combinator10 min
How To Build A Company With AI From The Ground Up
This presentation argues that AI must function as a company's central operating system rather than a peripheral tool, driving a shift toward closed-loop systems that render the entire organization queryable for automated decision-making. In this model, traditional middle-management hierarchies are eliminated and replaced by AI agents that execute engineering tasks and manage workflows, allowing human leaders to focus on strategy as founders, builders, or directly responsible individuals. By leveraging these "AI software factories," startups gain a decisive advantage over incumbents to achieve tenfold velocity increases and operate with human headcount replaced by optimized token usage.
Skydio HQ Tour: The $3.5B Bet on American Drone Manufacturing with CEO Adam Bry
An autonomous drone network delivers 24/7 public safety operations by deploying units from charging docks to locate missing persons, track suspects, and inspect infrastructure without human pilots. The system utilizes Beyond Visual Line of Sight waivers and Pathfinder AI to execute complex missions across diverse hardware, ranging from the indoor R10 tactical unit to the high-speed F10 fixed-wing prototype. Through a transparency portal and continuous real-world stress testing, the company has integrated these force-multiplier tools into law enforcement culture while scaling production for imminent general availability.
- Goldman Sachs10 min
Big Opportunities in Small Cap Equities
Following a period of underperformance, small and mid-cap stocks present a valuation opportunity driven by anticipated Federal Reserve rate cuts, a robust earnings cycle, and surging M&A activity. Investment strategies focus on high-potential sectors including biotechnology, semiconductor capital equipment, and defense innovation while cautiously monitoring domestic manufacturing and onshoring trends. Analysts expect strong January performance to catalyze investor inflows, though the outlook remains tempered by the need for sustained software stability and gradual credit market normalization.
Skydio Raises $110M Series F at $4.4B Valuation | CEO Adam Bry
Skydio recently closed an $110 million Series F round at a $4.4 billion valuation to scale its U.S.-manufactured autonomous drone fleet, which now secures a $50 million contract with the Army and serves 4,000 government and enterprise clients. The company differentiates itself from Chinese competitors through 100% domestic supply chain security and AI-driven agentic robotics that enable off-grid operations and reduce public safety response times by 70-80%. With plans to triple manufacturing capacity this year, Skydio aims to integrate its systems into 911 responses across the U.S. while expanding into energy utilities and battlefield intelligence.
- The Diary Of A CEO1h 33m
Stanford Neuroscientist: Can’t Remember Your Dreams? Your Brain May Be Warning You!
Neuroscientist David Eagleman outlines the biological imperatives of dreaming, which preserves visual cortex integrity, while advocating for continuous novelty-seeking and the "Ulysses Contract" as essential strategies to build cognitive reserve against age-related decline. He contrasts biological brains' capacity for one-trial learning with the data-heavy limitations of artificial intelligence, arguing that AI should eliminate repetitive friction but preserve the "virtuous friction" of human effort required for genuine creativity and social connection. Looking toward 2026 and 2027, Eagleman predicts the emergence of social platforms designed to force complexified intergroup relationships and introduces his upcoming book on self-imposed constraints to reshape behavior and identity.