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  1. Sequoia Capital19 min

    The Data Center is the New Unit of Compute: Crusoe CEO Chase Lochmiller

    Chase Lochmiller, David Kahn, Pat

    Crusoe Energy is rapidly constructing massive AI factories in Abilene, Texas, leveraging a vertically integrated supply chain to deliver gigawatts of power capacity decades ahead of traditional utility timelines. By repurposing stranded renewable energy and deploying advanced cooling architectures, the company accelerates the shift toward sovereign AI infrastructure while addressing critical bottlenecks in power and hardware availability. Founder Chase Lockmiller positions this industrial-scale approach as the mechanism to manufacture intelligence, creating a resilient foundation for the next phase of artificial general intelligence.

  2. Sequoia Capital18 min

    The Physical Turing Test: Jim Fan on Nvidia's Roadmap for Embodied AI

    Jim Fan

    NVIDIA Director Jim Phan outlines the "Physical Turing Test," a benchmark for robots performing complex physical tasks indistinguishable from human performance, while identifying data scarcity as the primary bottleneck for current systems. To overcome this, NVIDIA employs Simulation 2.0, utilizing generative models like Robocasa and video diffusion to exponentially scale training environments and introduce the GR00T N1 open-source model capable of zero-shot generalist control. This technological evolution aims to transition the physical world into a "Physical API," where software-defined skills enable autonomous robots to seamlessly handle household and industrial tasks, effectively embedding human-like dexterity into everyday infrastructure.

  3. Goldman Sachs22 min

    AI Exchanges: How tech giants are navigating the AI landscape

    Eric Sheridan, Allison Nathan, George Lee

    Major technology giants are sustaining record capital expenditures through 2025 to solidify AI infrastructure dominance, with Goldman Sachs projecting this peak intensity to slow in 2026 despite tariff-related cost increases. Executives from Meta, Alphabet, and Amazon characterize the sector as being in the early innings of a third computing shift, prioritizing defensive positioning and infrastructure monetization over immediate application-layer profitability. Although investor sentiment remains bifurcated by macroeconomic risks, current valuations reflect a strategic reliance on these incumbents' unprecedented balance sheet scale to navigate the transition from raw training to commercial deployment.

  4. Milken Institute30 min

    A Conversation with Nvidia CEO Jensen Huang | Global Conference 2025

    Jensen Huang, Michael Milken

    NVIDIA CEO Jensen Huang frames AI as a $100 trillion industrial revolution that creates "AI factories" to automate labor and reintegrate millions of workers into the global economy. Operating as an end-to-end infrastructure provider, the company builds massive, gigawatt-scale systems while arguing that unrestricted global chip trade is essential for establishing dominant U.S. standards. Through a culture of perpetual resilience and a focus on "Physical AI," NVIDIA aims to close the technology divide and drive GDP growth across healthcare, manufacturing, and robotics sectors.

  5. Sequoia Capital29 min

    AI's Trillion-Dollar Opportunity: Sequoia AI Ascent 2025 Keynote

    Pat Grady, Sonia, Konstantin Vargas

    Sequoia Capital outlines a strategic framework for the AI opportunity, predicting that the sector will disrupt both software and services markets by shifting value from selling tools to selling outcomes. The firm emphasizes investing in companies that demonstrate durable adoption and functional data flywheels, noting that 2024 marked a transition from hype to utility in vertical applications like healthcare and law. Looking ahead, the presentation predicts the emergence of an agent economy where interconnected agents manage resources and tasks, potentially enabling a "one-person unicorn" era through new management strategies.

  6. Sequoia Capital8 min

    Ambient Agents and the New Agent Inbox ft. Harrison Chase

    Harrison Chase

    LangChain CEO Harrison Chase introduces ambient agents as background systems designed to execute complex, multi-step operations by monitoring event streams rather than relying on direct chat input. These agents operate within a strict human-in-the-loop framework that utilizes patterns like action approval, editing, and time-travel rollback to ensure accuracy while preventing full autonomy. To support this architecture, LangChain has enhanced its LangGraph infrastructure for state persistence and scalability while deploying an Agent Inbox UI that enables users to manage long-running workflows through direct oversight and feedback integration.

  7. All-In Podcast52 min

    Doug Burgum, Secretary of the Interior | All-In DC

    Doug Burgum, David Friedberg

    Secretary of the Interior Doug Burgum, a former North Dakota governor and tech executive, has launched the National Energy Dominance Council to rapidly dismantle regulatory barriers hindering US LNG, nuclear, and critical mineral expansion. The initiative targets an energy emergency driven by surging AI and robotics demand by prioritizing Small Modular Reactors, modernizing federal permitting processes, and unlocking $8 trillion in untapped public land resources. Burgum argues that adopting a manufacturing-style approach and reducing bureaucratic duplication are essential for the United States to maintain energy independence and compete globally against China's aggressive infrastructure growth.

  8. Milken Institute56 min

    Game Changers: Unlocking the Global Sports Economy | Global Conference 2025

    Emmanuel Acho, Willow Bay, Sam Kennedy, Rich Paul, Alex Rodriguez, Jason Wright

    Moderated by Emanuel Ocho, a panel of five high-profile sports leaders including Alex Rodriguez, Rich Paul, and Sam Kennedy detailed the economic transformation of women's sports and the strategic necessity of institutional capital for franchise growth. The discussion highlighted how shifting from altruistic models to revenue-focused ecosystems has driven record attendance and a 200% surge in sponsorship, while establishing that sustainable success relies on defining culture through face-to-face interaction and long-term investment patience. By addressing market gaps in media coverage and merchandise, these leaders argued that balancing fiduciary duties with player well-being is essential for navigating an era where athletes now control their own narratives and investors target high-growth asset classes.

  9. a16z26 min

    Modernizing Warfare and Beyond

    Liz McNally, Qasar Younis, Erin Price-Wright

    The Defense Innovation Unit is accelerating the integration of dual-use commercial technology into the Department of Defense by partnering with companies like Applied Intuition to prototype and field software at scale. This strategy leverages new congressional flexibility and the Commercial Solutions Opening model to bridge the gap between agile industry innovation and military needs, addressing critical challenges in the Indo-Pacific against China's advancing autonomy capabilities. By prioritizing "dual fluency" talent and a venture-first procurement approach, DIU aims to modernize the defense industrial base and ensure the U.S. maintains a technological edge in software-defined warfare.

  10. Sequoia Capital48 min

    Building the System of Record for the AI Era ft Workday CEO Carl Eschenbach

    Carl Eschenbach, Sonya Huang, Pat Grady

    Workday CEO Carl Eschenbach is redefining the platform as a unified "Agent System of Record" to govern both human employees and AI agents across its database of over 70 million users. To monetize this shift, the company is deploying a multi-faceted pricing model involving seat-based uplifts, role-based agent fees, and consumption-based API access while utilizing strategic acquisitions like HiredScore to drive measurable productivity gains. Despite an 8% workforce restructuring to fund reinvestment, Eschenbach emphasizes that AI will serve as a growth engine rather than a cost-cutting tool, maintaining a human-in-the-loop approach for critical decisions to preserve the company's core values.

  11. Milken Institute23 min

    A Caregiving Conversation with Patrick Dempsey | Global Conference 2025

    Patrick Dempsey, Lisa Ling

    Founded by Patrick Dempsey following his mother's prolonged battle with ovarian cancer, the Dempsey Center provides free holistic care to cancer patients and their families across 32 states and four countries. The organization operates on a wraparound model that pairs medical treatment with services like nutrition counseling, yoga, and peer support while advocating for systemic insurance reforms to cover alternative therapies. Dempsey leverages his acting platform to expand the center's reach and fundraising efforts, aiming to reduce wait times for immediate intervention and establish a culture of caregiving that addresses the root causes of rising cancer rates.

  12. Milken Institute50 min

    The State of the Global Economy: Global Capital Markets | Global Conference 2025

    David Faber, Waleed Al Mokarrab Al Muhairi, Jane Fraser, Jenny Johnson, Harvey Schwartz, Andrew Sullivan

    Amidst rising tariff uncertainties and unsolvable fiscal deficits, major global investors from Carlyle, Mubadara, and Prudential are shifting capital allocation toward defensive balance sheets and the fastest-growing asset class, private credit. While short-term market volatility is expected as corporations delay supply chain transformations, long-term strategies increasingly prioritize U.S. assets and emerging markets like India alongside massive infrastructure investments in AI energy and data centers. Panelists project that despite immediate headwinds from regulatory burdens and debt concerns, artificial intelligence will ultimately drive superior productivity growth compared to fiscal policy measures over the next decade.

  13. Lex Fridman3h 1m

    Janna Levin: Black Holes, Wormholes, Aliens, Paradoxes & Extra Dimensions | Lex Fridman Podcast #468

    Janna Levin, Lex Fridman

    Physicist Jana Levin explores the fundamental nature of black holes, detailing their formation through stellar collapse, the detection of gravitational waves by LIGO, and the theoretical paradoxes involving quantum information and Hawking radiation. She contextualizes these extreme astrophysical events within broader cosmological questions regarding extra dimensions, dark matter, and the origins of life, while highlighting the decades-long human effort required to confirm Einstein's predictions. The discussion culminates in a reflection on how studying these entities serves as a crucial laboratory for unifying general relativity with quantum mechanics and underscores the philosophical value of scientific inquiry despite eventual cosmic entropy.

  14. Sourcery with Molly O'Shea45 min

    Why Bucky Moore Joined $30 Billion AUM Megafund Lightspeed

    Bucky Moore, Molly O'Shea

    Bucky Moore has joined Lightspeed as a Partner to lead early-stage enterprise investments, leveraging the firm's $30 billion asset base to support capital-intensive "new class" companies like OpenAI and SpaceX without raising a new fund. Moore emphasizes a people-first investment philosophy where deep relationship building and founder assessment supersede traditional valuation tactics, aiming to capture multi-trillion dollar outcomes in AI and robotics. By expanding Lightspeed's multi-asset capabilities and diversifying capital sources beyond traditional endowments, the firm aims to navigate the structural shifts required to sustain massive growth in the modern venture landscape.

  15. 20VC with Harry Stebbings1h 3m

    Bucky Moore @ Lightspeed Venture Partners: Why You Cannot Do VC If You Do Not Do Pre-Seed

    Bucky Moore, Harry Stebbings

    Following his move from Kleiner Perkins to Lightspeed Venture Partners as a partner, Bucky Brown outlines a strategic pivot toward supporting mega-platforms capable of deploying billions in capital to capture multi-trillion dollar AI outcomes. He argues that while model providers will dominate core categories, the "long tail" of specialized enterprise applications remains a viable space for early-stage ventures, provided investors prioritize deep domain expertise and founder selection over traditional market sizing. Brown warns that mid-sized funds face increasing obsolescence as the market polarizes, urging a conservative capital approach and a focus on "Team" to navigate the extreme capital intensity and rapid adoption defining the current AI era.