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  1. Milken Institute1h 1m

    Words That Work: 2025 Edition | Global Conference 2025

    Leslie Thurman, Frank Luntz

    The analysis outlines a sharply polarized American landscape where 80% of citizens view the nation as historically divided and demand tangible results over political rhetoric or abstract corporate values. It urges business leaders to abandon divisive terminology like "DEI" and "capitalism" in favor of resonant concepts such as "economic freedom" and "respect," while tailoring visual communications to evoke joy rather than fear. Without this strategic shift in language and imagery, the presentation warns that corporations face increasing legislative risks from a public backing wealth taxes and an unwavering political base that refuses to compromise.

  2. RAISE Summit20 min

    H Company CEO, Gautier Cloix: Beyond the Hype Leading Agentic AI into the Enterprise

    Gautier Cloix, Ruud

    H-Company, founded by former DeepMind employees and led by former Palantir executive CEO, has secured a record €220 million seed round to deploy its "Holo One" computer user agents that operate natively on digital interfaces without predefined APIs. The firm employs a forward-deployed engineer model to rapidly iterate within complex legacy enterprises across Europe and the US, targeting major clients like LVMH and Amazon while prioritizing cost-efficient generalist AI over siloed tools. With the strategic goal of reducing administrative burdens in sectors such as healthcare by shifting doctors' non-clinical time from 70% to near zero, the company plans to onboard key enterprise customers by year-end to refine its platform before global scaling.

  3. Goldman Sachs33 min

    Seth Klarman on Finding Value and Maintaining Discipline

    Seth Klarman, John Waldron

    Baupost Group's Scott Klarman articulates a 42-year investment philosophy that prioritizes capital preservation through strict margin of safety requirements and the avoidance of leverage, while evolving from traditional value metrics to include franchise value and private market dynamics. The firm's decision-making process relies on rigorous internal debate, pre-mortem risk analysis, and a culture that rewards intellectual honesty, allowing the team to navigate distressed assets and market volatility without succumbing to behavioral biases. Current portfolio construction maintains a balanced allocation across private credit, public equity, and real estate, explicitly targeting the downside risks posed by rising rates and commercial real estate stress while preparing the next generation for severe economic downturns.

  4. Milken Institute59 min

    Eco Edge: Investing in a Clean Economy | Global Conference 2025

    Leslie Kaufman, Areije Al Shakar, Mark Berryman, Nili Gilbert, Scott Jacobs

    Representatives from Generate Capital, Carbon Direct, Capricorn, and BE Ventures convened to analyze the $9 trillion real asset opportunity required to decarbonize heavy industry sectors that currently command 40% of global fossil fuel consumption. While market metrics show a strategic shift from mission-driven to profit-driven models with private equity returns reaching the high teens, political uncertainty and the Inflation Reduction Act's implementation remain primary variables for the next 18 months. The panel identified specific growth vectors including AI-driven microgrids, industrial hydrogen, and small modular reactors as critical mechanisms to bridge the gap between economic viability and net-zero targets.

  5. Milken Institute51 min

    Unlocking Health Data | Global Conference 2025

    Richard Lui, Ramin Bastani, David Feinberg, Deborah Kilpatrick, Hon Pak

    A panel of healthcare leaders from Healthvana, Oracle Health, Sonder Capital, and Samsung discussed the shift from data-rich but information-poor systems to liquid, human-centric models that prioritize patient trust and interoperability. The group highlighted how AI tools are already reducing clinical burnout, improving predictive accuracy for long-term health events, and enabling dynamic consent mechanisms to protect patient ownership. Looking toward a decade-long horizon, the speakers anticipate a paradigm shift where quantum computing and decentralized care empower patients to manage their health through seamless data integration rather than relying solely on traditional specialist visits.

  6. RAISE Summit27 min

    Eric Schmidt & Andrew Feldman: The Race to SuperIntelligence

    Eric Schmidt, Andrew Feldman

    Cerebras Systems CEO Andrew Gerrandt asserts that the company's Wafer Scale Engine architecture delivers inference performance nearly two orders of magnitude faster than competitors, driving a market shift from training-dominant to inference-heavy workloads. This hardware acceleration, combined with strategic open-source adoption and co-designed software, has compressed industrialization timelines from decades to five years while exposing critical bottlenecks in global energy infrastructure and data sovereignty. As the industry navigates an uncharted S-curve of explosive growth, geopolitical competition and alignment risks now define the trajectory toward autonomous, on-device AI integration.

  7. Milken Institute1h 0m

    Common Sense from Uncommon Investors | Global Conference 2025

    Michael Milken, Victor Khosla, Marc Lipschultz, Robert F. Smith, Jonathan D. Sokoloff, Anne Walsh

    On May 5, 2025, a panel of investment leaders including Anne, Jonathan, Robert, Mark, and Victor analyzed a geopolitical landscape upended by U.S. fiscal policy and trade shifts that have heightened market volatility and debt concerns. Despite these macroeconomic headwinds, the group highlighted robust opportunities within private equity, generative AI, and private credit, citing specific strategies such as expanding employee ownership, deploying "agentic" AI solutions, and providing stable capital for hyperscale infrastructure. The discussion concluded with a focus on governance and succession, emphasizing the necessity of shifting from short-term arbitrage to long-term value creation while mentoring the next generation of investment professionals to navigate structural market changes.

  8. RAISE Summit20 min

    Eric Schmidt: AI and the Genesis of a New Epoch

    Eric Schmidt, Henri Delahaye

    Dr. Eric Schmidt characterizes the current technological landscape as a new epoch driven by the imminent arrival of reasoning-based AI, predicting that Artificial General Intelligence and superintelligence will emerge within four to six years. The discussion highlights a geopolitical divergence where the United States pursues capital-intensive closed-source models while China leverages open-weight systems, creating a strategic risk where global usage may outpace Western control. Schmidt concludes that massive infrastructure investment in compute capacity will outlast concerns of a market bubble, as autonomous systems will drive unprecedented growth in mathematics and software development independent of human data constraints.

  9. Milken Institute28 min

    A Conversation with the President of Paraguay H.E. Santiago Peña | Global Conference 2025

    Santiago Peña, Daniel Yergin

    Under President Santiago Pena's leadership, Paraguay has secured a positive credit outlook from S&P Global and a diversified economy driven by industrial growth and renewable energy exports. The government's strict "no shortcuts" fiscal policy and simplified tax regime have stabilized currency and attracted major foreign investment, particularly from Brazil's manufacturing sector and global tech firms seeking data center connectivity. As the nation pursues OECD membership and expands trade agreements with the EU and UAE, it positions itself as a top-performing Latin American economy with significant potential for green hydrogen and digital infrastructure development.

  10. Milken Institute1h 1m

    Things That Will Blow Your Mind | Global Conference 2025

    Richard Sandler, JC Btaiche, Rowland Illing, Christyl Johnson, Jeb Terry, Crystal Johnson

    Led by moderator Richard Sandler, a panel of industry leaders from NASA, FUSE, AWS, and Cosm explored the technological interdependencies required to achieve sustainable lunar habitation by 2040, commercial fusion energy within a decade, and AI-driven healthcare advancements. Speakers detailed critical innovations ranging from NASA's use of digital twins and inflatable habitats for Mars missions to FUSE's "Radiation as a Service" model and AWS's multimodal generative AI applications that accelerate biological discovery. The consensus emphasized that while government funding is necessary, scalable progress in space, energy, and health relies heavily on structured public-private partnerships to incentivize private capital and navigate the growing energy demands of these transformative sectors.

  11. a16z49 min

    America's Energy Problem: We Need A New Grid

    David Ulevitch, Erin Price-Wright, Ryan McEntush, Aaron

    This event addresses the critical ossification of the U.S. electrical grid, where aging infrastructure, severe transformer backlogs, and a dispersed skilled workforce have stalled megaproject development. Panelists argue that the solution lies in a decentralized "leapfrog" strategy combining on-site generation, Small Modular Reactors, and AI-driven management to bypass interconnection bottlenecks. The discussion highlights urgent investment opportunities in grid visibility software, industrial robotics, and supply chain diversification to meet the explosive power demands of data centers and EVs.

  12. Y Combinator27 min

    Nobel Laureate John Jumper: AI is Revolutionizing Scientific Discovery

    John Jumper

    Google DeepMind leader John Jumper presents AlphaFold 2, an AI system that revolutionizes structural biology by accurately predicting protein 3D structures to bridge the massive gap between sequenced genes and experimentally solved forms. The technology's superior accuracy, validated by a thirty-fold reduction in error rates at CASP14 and the release of over 200 million predictions, has accelerated drug discovery and enabled novel applications like re-engineered molecular syringes for targeted therapy. This shift allows experimentalists to advance the pace of biological research by 5 to 10 percent, transforming AI from a narrow computational tool into a fundamental amplifier for scientific discovery.

  13. Milken Institute1h 0m

    Strategies for Expanding Affordable Housing | Global Conference 2025

    Jennifer Sondag, Stephen J. Cloobeck, Scott Epstein, Martin Muoto, Shane Phillips, Stephanie Rawlings-Blake

    A high-stakes panel on California's housing crisis converges on the conclusion that a five-million-unit supply shortage, exacerbated by regulatory burdens like CEQA and restrictive zoning, necessitates urgent legislative and structural reform. Key figures including developer Martin and gubernatorial candidate Stephen Zake advocate for dismantling bureaucratic barriers, citing cost disparities between inefficient nonprofit construction and private sector models, while highlighting successful precedents in Cambridge and New Zealand. The discussion culminates in a strategic pivot toward public-private partnerships and single-family upzoning, arguing that aligning private capital with social impact is essential to resolve the workforce housing mismatch and lower costs for essential workers.

  14. Milken Institute59 min

    US Economic Competitiveness in a Changing World | Global Conference 2025

    Stephanie Flanders, Gary Cohn, Kevin McCarthy, Peter Orszag, Ruth Porat, Glenn Youngkin

    Panelists project the U.S. economy will maintain long-term resilience driven by global reserve currency status and corporate investment, despite short-term fiscal strain and a macro-resilience decline caused by supply chain diversification away from China. To address structural deficits, the discussion emphasizes accelerating GDP growth through aggressive AI adoption, a nuclear energy revolution to power digital infrastructure, and tax policy extensions that prioritize domestic manufacturing over antitrust enforcement. Simultaneously, the administration faces a critical tension between strict immigration enforcement and the urgent need to attract global talent, a challenge highlighted by Virginia's $100 billion in recent corporate commitments and its pivot toward non-traditional workforce development pathways.

  15. All-In Podcast1h 31m

    Grok 4 Wows, The Bitter Lesson, Third Party, AI Browsers, SCOTUS backs POTUS on RIFs

    Travis Kalanick, Keith Rabois, Chamath, Jason, Friedberg

    Travis Kalanick unveiled his "Bowl Builder" robotic food assembly machine designed to slash labor costs to 10% of revenue, while Elon Musk confirmed ongoing discussions with Pony AI to license autonomous driving technology for both passenger and food delivery applications. These logistical advances align with Musk's announcement that Grok 4 has outperformed competitor models by scaling general computation and transitioning exclusively to synthetic training data. Amidst these technological shifts, Musk also proposed a new political party focused on fiscal responsibility to influence congressional races, a move supported by the Supreme Court's recent ruling granting the President broad authority to execute federal workforce reductions.