Latest Interviews
Showing 1351–1365 of 5,336 transcripts.
Clear all filters- The Diary Of A CEO1h 31m
The Foot Expert: Your Toes Can Predict If You’ll Die Early! This Will Fix Plantar Fasciitis!
Dr. Courtney Conley and host Stephen Bartlett examine the critical link between foot health, longevity, and mental well-being, highlighting how modern footwear compromises natural mechanics to cause widespread mobility issues. The discussion details how narrow, cushioned shoes exacerbate conditions like plantar fasciitis and depression, while prescribing a transition to zero-drop footwear and specific strength exercises to restore intrinsic muscle function. By addressing root causes such as overstriding and weak musculature, the speakers advocate for a functional approach that reduces cardiovascular and mortality risks while empowering individuals to maintain movement as a fundamental mode of survival.
- Milken Institute21 min
A Conversation with Eric Schmidt | Global Conference 2025
Eric Schmidt analyzes the evolving Ukraine conflict as a volatile stalemate driven by massive drone production, automated sensor-to-shooter loops, and the obsolescence of traditional armored platforms like tanks and aircraft carriers. He contrasts Ukraine's rapid, two-week innovation cycles against the Pentagon's sluggish 16-year procurement process, arguing that rigid bureaucratic structures prevent the U.S. from adopting necessary autonomous systems. Schmidt concludes that to counter modern hypersonic threats and future high-intensity warfare, the U.S. must pivot from expensive stationary assets to affordable, internet-prosecuted robotic forces integrated with its domestic startup ecosystem.
- Jane Street1h 20m
Building Tools for Traders with Ian Henry
Ian Henry, Ron Minsky, Mark Mandelbaum, Mark Mirchandani, David Eastman, Brian Dorsey
Ian Henry, a Jane Street engineer who transitioned from general web development to options trading tools, leverages the firm's custom OCaml ecosystem to build high-density interfaces that eliminate mouse usage and manage complex volatility surfaces. His recent work includes creating Bauble, a live 3D graphics environment in the Janet language that demonstrates how side projects using image-based state serialization and novel macro systems can rapidly inform internal production tooling. Through this process, Henry illustrates how Jane Street bridges the gap between low-latency exchange architecture and expert user needs by prioritizing type safety, extreme information density, and a parallel software universe free from standard web protocols.
How Wander Raised Over $100M+ to Reinvent Luxury Travel
Wander, a verticalized vacation rental marketplace led by founder John Andrew, recently secured a Series B term sheet with QED to scale its curated inventory of top-tier properties beyond 1,000 locations. The company differentiates itself through a proprietary AI-driven operating system that automates 60% of management tasks and maintains strict brand safety standards while transitioning from an asset-heavy balance sheet to a REIT-based model. With a $40 million GMV run rate and a $100 million annual revenue target, Wander is restructuring into business units to support efficient growth toward Series C while prioritizing operational frugality and ethical cultural fit.
- Milken Institute1h 13m
The Milken-Motsepe Prize in FinTech Pitches and Grand Prize Ceremony | Global Conference 2025
Milken, Motsepe, Emily Musil, Meghan McCormick, Precious Moloi-Motsepe, Sam Njuguna, Ola Oyetayo, Jonathan Wilson
The 2025 Milken-Motsepe Prize awarded $2 million to ten semi-finalists to support African-led FinTech innovations targeting underbanked populations, with Virto securing the $1 million grand prize for its cross-border payment infrastructure. Key figures including Mike Milken and Patrice Motsepe emphasized the program's role in leveraging Africa's demographic growth and entrepreneurship to catalyze follow-on investment and impact over one million lives since its inception. Building on this momentum, the initiative launched a new accelerator and announced an upcoming challenge cycle in AI and Manufacturing to further address financial inclusion and infrastructure gaps across the continent.
- a16z1h 18m
Rick Rubin: Vibe Coding is the Punk Rock of Software
Rick Rubin, Marc Andreessen, Ben Horowitz, Anjney Midha, Erik Torenberg
Rick Rubin introduces "vibe coding" as a methodology merging the ancient spiritual principles of the Tao Te Ching with modern AI to democratize creation for non-technical users. The discussion outlines how this approach treats AI as a tool for human expression rather than an autonomous creator, aiming to counteract the homogenization of global culture and narrow demographic biases in current tech development. Ultimately, the event advocates for a future of education focused on cultivating taste and self-knowledge, allowing artists to leverage AI to raise creative ceilings while maintaining authentic individual agency.
- a16z21 min
7 More Healthy Years: What We Can Learn from Super Agers
The proposed healthcare strategy shifts focus from unproven aging reversal to preventing the "big three" age-related diseases through modifiable lifestyle factors and emerging medical technologies. By integrating personalized omics data, AI-driven risk profiling, and novel treatments like GLP-1 drugs and cellular therapies, this approach aims to extend healthspan by seven years for populations globally. This evidence-based framework prioritizes immediate disease mitigation over theoretical longevity, leveraging a 20-year incubation window to fundamentally redefine the standard of care.
- Goldman Sachs24 min
How AI, tariffs, and the energy transition are reshaping infrastructure investing
Large institutional investors have allocated 6% to 7% of assets to infrastructure, a sector that generated nine percent returns since 2022 while evolving from traditional transport dominance to focus on energy transition and digital assets like AI-driven data centers. Goldman Sachs identifies key opportunities across four segments, noting that solar plus storage is now cost-competitive and that European markets are gaining traction due to Germany's massive infrastructure plan, despite geopolitical and liquidity risks in specialized areas. To capitalize on these secular trends in decarbonization and digitalization, investors utilize closed-ended funds targeting mid-teens returns or evergreen vehicles for long-term capital appreciation.
- Sequoia Capital38 min
From Data Centers to Dyson Spheres: P-1 AI's Path to Hardware Engineering AGI
Paul Eremenko, Sonya Huang, Pat Grady
P1.ai is launching its AI engineering agent "Archie," which addresses the scarcity of physical design data by synthesizing massive, physics-informed datasets to train specialized models for hardware creation. Initially targeting data center cooling applications in 2025, the system operates as a collaborative team member that orchestrates existing CAD and simulation tools to perform complex design synthesis and error correction at entry-level engineer proficiency. With angel investment from Jeff Dean, the company aims to scale the agent's capabilities from residential cooling to aerospace domains over the next four years, ultimately striving for Engineering AGI defined by self-reflection and domain generalization.
- Milken Institute1h 3m
Business and the Global Economy: Driving Growth and Innovation | Global Conference 2025
Conrad Kiechel, Gerard Baker, Ajay Banga, Mariam bint Mohammed AlMheiri, Rich Lesser, Gilberto Tomazoni, Jerry Baker
At the 28th Milken Institute Global Conference, panelists led by World Bank officials and BCG executives discussed strategies to navigate global trade fragmentation and a looming labor surplus in developing nations. The discussion highlighted the critical need for public-private partnerships to fund infrastructure and energy grids capable of supporting both AI adoption and agricultural transformation. Experts concluded that while geopolitical tensions threaten traditional globalization, targeted regional integration and regulatory reforms can unlock new growth vectors for the global economy.
- Milken Institute1h 1m
The Global Quest to Reinvent the City | Global Conference 2025
Maggie Switek, Mikkel Bülow-Lehnsby, Thomas Heatherwick, Matthew Kahn, Erin L. Murphy
A global panel of experts and investors, including Urban Partners' Mikael Lindberg and architect Thomas Heatherwick, outlines a strategic shift toward resilient, human-centric cities that address the impending doubling of the urban population and severe climate threats in Southeast Asia. The discussion highlights the transition from fragmented asset management to integrated "live, work, play" districts, leveraging AI-driven tools and public-private partnerships to overcome the "blandemic" of sterile architecture and rising sea-level risks. Ultimately, the consensus emphasizes that aligning capital with emotional engagement and functional design will drive the economic viability necessary to build carbon sinks and adaptive infrastructure in rapidly urbanizing regions.
- All-In Podcast1h 2m
Senator Ron Johnson on the Senate showdown over Trump's Big Beautiful Bill | All-In Interview
Ron Johnson, Trump, Friedberg, Chamath, Jason
Senator Mike Johnson warns that projecting federal spending to reach $7.3 trillion annually could swell the national debt to $63 trillion by 2035, a trajectory he argues the current House reconciliation bill fails to address. While acknowledging the limitations of budget reconciliation, he vows to vote against the legislation unless it commits to returning spending to pre-pandemic levels and codifies efficiency findings through rescission rather than broad political packages. Joined by allies like Senators Rand Paul and Mike Lee, Johnson insists that without immediate corrective measures to curb interest costs and discretionary spending, the United States risks a debt spiral that would fundamentally erode the conservative movement and the economy.
- a16z16 min
Sovereign AI: Why Nations Are Building Their Own Models
Anjney Midha, Guido Appenzeller
Saudi Arabia has announced the construction of a $100 billion to $250 billion local hyperscaler named "Humane" to establish sovereign AI infrastructure capable of running 500-megawatt clusters that prioritize national control over cultural and informational output. This strategic pivot distinguishes itself from traditional cloud computing by treating AI as a critical cultural asset, requiring nations to build independent "AI Factories" to prevent foreign entities from dictating model values and societal narratives. The resulting geopolitical landscape favors a competitive market ecosystem where nations secure their own inference capabilities, potentially avoiding total centralization while mitigating risks associated with reliance on foreign foundation models.
- All-In Podcast1h 34m
Bond crisis looming? GOP abandons DOGE, Google disrupts Search with AI, OpenAI buys Jony Ive's IO
Jony Ive, Chamath, Jason, Sacks
The U.S. Treasury struggled to sell $16 billion in 20-year bonds, triggering yield spikes that depressed stock indices and highlighted unsustainable debt costs driven by new tax legislation. In the technology sector, Google pivoted toward subscription-based AI search services while OpenAI acquired Jonathan Ive's firm for $6 billion to develop high-end hardware. Simultaneously, the United States launched an "AI Diplomacy" framework to secure Middle Eastern infrastructure investment, while medical breakthroughs saw the first successful in vivo CRISPR gene editing in a pediatric patient.
- Milken Institute56 min
Rising Strong: Los Angeles' Path to Recovery | Global Conference 2025
Michelle Stevenson, Elex Michaelson, Karen Bass, Lindsey Horvath, Cinny Kennard, Evan Spiegel
Hosted by the Milken Institute on January 12, a panel of Los Angeles officials and philanthropists assessed recovery efforts following the January 7, 2024 wildfires that destroyed over 16,000 structures. While Mayor Karen Bass and County Supervisor Lindsay Horvath highlighted rapid debris removal and AI-driven permit processing as key successes, the discussion also addressed systemic hurdles including insurance underwriting bottlenecks and infrastructure fragmentation across the region's 88 cities. With Governor Newsom requesting $39 billion in federal aid and philanthropists like Evan Spiegel pledging long-term support, the event emphasized balancing accelerated rebuilding timelines with rigorous safety standards and regional consolidation strategies.