Marc Andrusko
Showing 1–4 of 4 transcripts.
- a16z14 min
How AI Agents Will Transform in 2026 (a16z Big Ideas)
Marc Andrusko, Stephanie Zhang, Olivia Moore, Steph Ng
The event details a fundamental shift from reactive prompt-based interfaces to proactive AI agents that autonomously diagnose issues and execute actions, expanding the addressable market from software spending to the broader labor economy. Speakers discuss how design priorities are evolving toward machine legibility to enable high-autonomy applications in sales, security, and content discovery, while voice AI agents achieve scalable enterprise deployment in healthcare, finance, and customer service by outperforming humans in compliance and multilingual accuracy. This transition is redefining the human-in-the-loop dynamic, where critical decisions retain oversight while routine tasks are increasingly automated to drive efficiency across nearly every industry vertical.
- a16z30 min
How AI is Powering Payments, with Greg Ulrich of Mastercard
Greg Ulrich, Marc Andrusko, Mark
MasterCard Chief AI and Data Officer Greg Ulrich outlines a strategic framework that segments artificial intelligence into four pillars—Safer, Smarter, More Personal, and Stronger—to address specific business needs ranging from fraud detection to internal operational efficiency. This approach has yielded concrete implementations such as the "Decision Intelligence" system for ecosystem-wide security, the "Shopping Muse" chatbot for personalized recommendations, and a Retrieval Augmented Generation-based onboarding assistant that maintains accuracy through human oversight. Looking ahead, the organization emphasizes cautious adoption of generative AI in regulated environments while prioritizing data security, multi-modality, and the development of reasoning models that explicitly acknowledge uncertainty.
- a16z14 min
How AI Will Transform Accounting: A $100B Opportunity Explained
Seema Amble, Marc Andrusko, Michelle Kung
Facing a projected 75% retirement wave among CPAs and a 16% workforce decline since 2019, the accounting industry is under pressure to automate manual tasks amidst outdated infrastructure and a resistance to AI due to accuracy requirements. Major firms are shifting from billable-hour models to fixed-fee structures, with top-tier organizations preparing to invest up to $500 million in technology to transition professionals from data entry to advisory roles. This strategic realignment aims to solve labor shortages while reducing consumer costs and accelerating service delivery through the adoption of AI for unstructured data ingestion and regulatory research.
- a16z15 min
"Death of a Salesforce”: Why AI Will Transform the Next Generation of Sales Tech
The sales technology sector is undergoing a fundamental transformation from manual data entry to AI-native systems that automatically capture unstructured, real-time interactions across diverse channels to serve as a comprehensive "true second brain." This shift is eroding traditional Sales Development Representative roles while creating demand for intelligent pipeline automation, digital workers, and real-time coaching tools that enable hyper-personalized engagement. Consequently, organizations are redefining the system of record to include multimodal data, fostering cross-functional alignment between marketing, sales, and engineering through shared ecosystems centered on customer outcomes rather than activity metrics.