newsfilter
← Latest News
GlobeNewswire·

10 Presentations on Day 3 of Bionano Symposium 2026 Showcase OGM's Utility in Unraveling the Complex Puzzles of Constitutional Genetic Disorders

BNGO
  • Bionano Genomics presented highlights from Day 3 of the Bionano Symposium 2026 in San Diego, focusing on Optical Genome Mapping (OGM) for constitutional genetic disorders.
  • The symposium attracted over 1,200 participants from 73 countries, with Day 3 featuring presentations from Japan, India, Brazil, the Netherlands, Turkey, and the US.
  • Chief Medical Officer Dr. Alka Chaubey emphasized OGM's ability to deliver unbiased, comprehensive structural variant detection with positional context, aided by VIA software to standardize workflows.
  • Dr. Yassmine Akkari highlighted OGM's role in bridging cytogenetics and molecular genomics to uncover variants missed by traditional methods in rare disorders.
  • Dr. Mehmet Burak Mutlu demonstrated OGM's utility in autism spectrum disorder, identifying relevant variants in 24% of 34 cases, including repeat expansions missed by exome sequencing.
  • Drs. Li Fu and Debopriya Chakraborty revealed OGM's capacity to detect cryptic translocations in recurrent pregnancy loss cases that conventional karyotyping often misses.
  • Researchers including Dr. Walaa Darwiche and Dr. Laila El Khattabi showed OGM's ability to resolve complex copy number variations and mosaicism across diverse populations.
  • Dr. Karthik Bharadwaj Tallapaka demonstrated OGM detecting structural variants associated with muscular dystrophy and infertility in India, noting the need for population-specific databases.
  • Dr. Nikhil Sahajpal presented data showing OGM identified pathogenic variants in 20% of 133 rare disease subjects, 12% of CMA/WES-negative cases, and 5% of WGS-negative cases.
  • A live panel discussion moderated by Dr. Chaubey covered best practices for OGM implementation, resolving complex disorders, and future research directions.
  • CEO Erik Holmlin stated that OGM is breaking barriers in understanding constitutional disorders with impressive geographic breadth and that these conditions are collectively common.
  • Bionano Symposium 2026 continues on February 26, 2026, with Day 4 focusing on genome landscape analysis using Ionic, Saphyr, Stratys, and VIA platforms.
  • Session recordings are available on-demand via the Bionano YouTube channel, while the live panel discussion Q&A is not archived.
  • Symposium registration remains free for all attendees, who can also explore posters on the virtual platform.