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Alpha Tau and Samsung Medical Center Sign MOU to Explore Clinical Trial of Alpha DaRT® for Pancreatic Cancer Patients in Korea

  • Alpha Tau Medical Ltd. signed an MOU with Samsung Medical Center (SMC) in Seoul for a potential first clinical trial of Alpha DaRT in South Korea, subject to regulatory & ethics approvals.
  • The trial targets pancreatic cancer patients at SMC, which ranks fifth globally & first in Korea for oncology.
  • In Korea, only one in five pancreatic cancer patients undergo surgery, & the disease's death rate rose over 6% in 2025, marking the steepest increase among major cancers.
  • Pancreatic cancer is Korea's fourth leading cause of cancer death, with a 2023 diagnosis count of 9,748 & a five-year relative survival rate of 17.0%, the lowest of any cancer in the country.
  • Fewer than one in six Korean patients are diagnosed while the cancer is confined to the pancreas, while more than 40% are diagnosed after it has spread to distant organs.
  • SMC's Pancreatobiliary Cancer Center has performed over 4,000 pancreatectomies for pancreatic cancer between 2008 & 2025.
  • Alpha DaRT is an alpha-radiation therapy using radium-224 sources to deliver high-energy alpha particles that destroy tumors while sparing surrounding healthy tissue.
  • Alpha Tau aims to potentially expand its pancreatic cancer program to six countries across North America, Europe, the Middle East, & Asia following this collaboration.
  • Alpha DaRT is currently approved commercially only in Japan for unresectable locally advanced or recurrent head & neck cancer, with no other commercial approvals outside of approved trials.
  • SMC was ranked fifth in the world & first in Korea in oncology in Newsweek's World's Best Specialized Hospitals 2027.