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Crinetics Pharmaceuticals Reports Second Quarter 2026 Financial Results and Provides Business Update

  • Vertex Pharmaceuticals agreed to acquire Crinetics for $85.00 per share, resulting in a total equity value of approximately $10.0 billion or $8.8 billion net of cash acquired.
  • The transaction received unanimous approval from both company boards and is expected to close in the third quarter of 2026 subject to regulatory & stockholder approvals.
  • Crinetics reported net product revenue of $24.0 million for the second quarter of 2026 from its commercial product PALSONIFY® (paltusotine).
  • Total revenue for the quarter ended June 30, 2026, reached $25.1 million, a significant increase from $1.0 million in the same period in 2025.
  • Crinetics received Rare Pediatric Disease Designation from the FDA for its investigational candidate atumelnant used for congenital adrenal hyperplasia.
  • Prescriber breadth expanded to 385 unique healthcare providers within the first three quarters of the PALSONIFY launch.
  • Over 70% of patients treated with PALSONIFY as of the end of Q2 2026 were covered by reimbursed therapy.
  • Research & development expenses for the quarter were $99.9 million, driven by increased clinical program investments & personnel costs.
  • Selling, general & administrative expenses totaled $57.6 million, reflecting commercial infrastructure investments & costs related to the Vertex transaction.
  • The company reported a net loss of $120.9 million for the quarter, compared to $115.6 million in the prior year period.
  • Cash, cash equivalents, & investment securities totaled $1.2 billion as of June 30, 2026.
  • Crinetics withdrew its previously issued financial guidance & will not host an earnings conference call due to the proposed Vertex acquisition.