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CSO of Napo Pharmaceuticals, a Jaguar Health Family Company, and Clinical Investigators Evaluating Crofelemer Conduct Panel Discussion at Pediatric Gastroenterology Conference in Dubai (UAE)

  • Jaguar Health's subsidiary Napo Pharmaceuticals recapitulated a panel discussion on October 30, 2026, at the 2nd Best of Elite Ped-GI meeting in Dubai regarding intestinal failure & parenteral nutrition.
  • Panelists included Dr. Mohamad Miqdady, Dr. Christos Tzivinikos, & Pravin Chaturvedi, who discussed clinical challenges of microvillus inclusion disease (MVID) & short bowel syndrome (SBS-IF).
  • The panel reviewed data showing that over one year of liquid oral crofelemer treatment reduced parenteral support needs & improved growth parameters in pediatric MVID & SBS-IF patients.
  • Patients with intestinal failure require lifelong total parenteral nutrition (TPN) which carries serious risks, driving the need for alternative therapies like crofelemer.
  • Napo remains focused on its global development program for crofelemer powder for oral solution as an adjunctive therapy to parenteral support for rare intestinal failure diseases.
  • Data presented in June 2026 at the ESPGHAN meeting confirmed substantial reductions in weekly parenteral support requirements normalized to body weight with no significant clinical or laboratory abnormalities.
  • An ongoing randomized double-blind placebo-controlled crossover study in MVID patients is being conducted to meet regulatory requirements.
  • The company targets a New Drug Application (NDA) filing for MVID in mid-2027 based on expected clinical milestones from the pediatric program.