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Incyte to Acquire Vega Therapeutics, a Wholly Owned Subsidiary of Star Therapeutics, Expanding its Hematology Portfolio into Bleeding Disorders

  • Incyte has entered a definitive agreement to acquire Vega Therapeutics, a wholly owned subsidiary of Star Therapeutics, for an upfront payment of $1.25 billion.
  • Star Therapeutics may receive up to $750 million in additional payments upon achieving sales milestones, bringing the total potential consideration to $2.0 billion.
  • The acquisition will add VGA039, a novel investigational monoclonal antibody targeting Protein S, to Incyte's hematology portfolio.
  • VGA039 is in Phase 3 pivotal development (VIVID-6 study) for von Willebrand disease (VWD), the most common inherited bleeding disorder affecting approximately 135,000 people in the U.S.
  • The therapy aims to be the first subcutaneous prophylactic option for VWD, offering a once-monthly dosing regimen compared to current treatments requiring frequent intravenous infusions.
  • VGA039 holds FDA designations including Breakthrough Therapy, Fast Track, orphan drug, and rare pediatric disease status.
  • The transaction has been approved by both companies' Boards of Directors and is expected to close in the third quarter of 2026, pending Hart-Scott-Rodino review.
  • Incyte expects to record an R&D charge of approximately $1.25 billion related to the equity acquisition in its third quarter and full year 2026 financial results.
  • An analyst and investor call is scheduled for Monday, June 8, 2026, at 8:00 a.m. ET to discuss the acquisition details.