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US Patent Applications (USPTO)·

New patent granted for: Immuno-Based Botulinum Toxin Serotype a Activity Assays

The present specification discloses SNAP-25 compositions, methods of making .alpha.-SNAP-25 antibodies that bind an epitope comprising a carboxyl-terminus at the P.sub.1 residue from the BoNT/A cleavage site scissile bond from a SNAP-25 cleavage product, .alpha.-SNAP-25 antibodies that bind an epitope comprising a carboxyl-terminus at the P.sub.1 residue from the BoNT/A cleavage site scissile bond from a SNAP-25 cleavage product, methods of detecting BoNT/A activity, and methods of detecting neutralizing .alpha.-BoNT/A antibodies.