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Pyxis Oncology Announces Up to $114 Million Private Placement Financing to Advance MICVO Through Key Clinical Milestones

  • Pyxis Oncology, Inc. entered a private placement agreement expected to generate approximately $50 million in gross proceeds upfront & an additional $64 million if accompanying warrants are exercised in full.
  • Financing led by BVF Partners L.P. with participation from GordonMD Global Investments, RTW Investments, & Coastlands Capital.
  • Proceeds will extend the company's cash runway into the second quarter of 2027 to support follow-up for 2L+ R/M HNSCC patients treated with MICVO at or below a dose cap.
  • The company expects updated Phase 1 monotherapy data for 2L+ R/M HNSCC in Fall 2026, including analysis of patients treated at 5.4 mg/kg IV Q3W.
  • Updated Phase 1/2 combination data for MICVO with pembrolizumab in first-line R/M HNSCC is expected in the fourth quarter of 2026.
  • Terms include the sale of 19,600,153 common stock shares at $2.551 per share & warrants to purchase an equal number of shares at an exercise price of $3.289 per share.
  • The private placement is expected to close on or about July 2, 2026, subject to customary closing conditions.
  • Wells Fargo Securities acted as the sole placement agent for the transaction.
  • MICVO received Fast Track Designation from the FDA for treating adult patients with R/M HNSCC who have progressed following platinum-based chemotherapy & anti-PD-(L)1 therapy.