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TYRA BIOSCIENCES AND BCAN ESTABLISH MAY 21 AS UPPER TRACT UROTHELIAL CANCER (UTUC) AWARENESS DAY

  • Tyra Biosciences and the Bladder Cancer Advocacy Network (BCAN) established Upper Tract Urothelial Cancer (UTUC) Awareness Day on May 21, 2026, to raise disease recognition & highlight the need for innovation.
  • UTUC is a rare cancer affecting the kidney & ureter lining with a high prevalence of FGFR3 alterations & currently lacks an established systemic standard of care.
  • Standard treatments often involve endoscopic ablation or nephroureterectomy, which can cause long-term complications & result in kidney loss.
  • Tyra is dosing patients with dabogratinib, an investigational oral FGFR3-selective inhibitor, in the Phase 2 SURF303 study for low-grade UTUC.
  • Dabogratinib is the only oral therapeutic candidate in clinical development for low-grade UTUC & aims to provide a kidney-sparing treatment option.
  • The collaboration seeks to address patient isolation, build a community, & encourage further education, advocacy, & research for UTUC.