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Lex Fridman2h 13m

Dmitry Korkin: Evolution of Proteins, Viruses, Life, and AI | Lex Fridman Podcast #153

Dmitry Korkin, Lex Fridman

Interview

Dmitry Korkin explores the modular nature of protein structures and the transformative impact of AlphaFold on predicting biological complexity, while detailing the specific viral mechanics of SARS-CoV-2 spikes and their evolutionary trajectories. He discusses the intersection of machine learning and structural biology to forecast pathogenicity risks, emphasizing that experimental validation remains the critical bottleneck for therapeutic applications. Korkin concludes with a broader perspective on the rarity of life in the universe and the historical evolution of expert systems from early cheminformatics to modern AI-driven discovery.