Latest Interviews
Showing 166–180 of 541 transcripts.
Clear all filters- Goldman Sachs33 min
Seth Klarman on Finding Value and Maintaining Discipline
Baupost Group's Scott Klarman articulates a 42-year investment philosophy that prioritizes capital preservation through strict margin of safety requirements and the avoidance of leverage, while evolving from traditional value metrics to include franchise value and private market dynamics. The firm's decision-making process relies on rigorous internal debate, pre-mortem risk analysis, and a culture that rewards intellectual honesty, allowing the team to navigate distressed assets and market volatility without succumbing to behavioral biases. Current portfolio construction maintains a balanced allocation across private credit, public equity, and real estate, explicitly targeting the downside risks posed by rising rates and commercial real estate stress while preparing the next generation for severe economic downturns.
- RAISE Summit27 min
Eric Schmidt & Andrew Feldman: The Race to SuperIntelligence
Cerebras Systems CEO Andrew Gerrandt asserts that the company's Wafer Scale Engine architecture delivers inference performance nearly two orders of magnitude faster than competitors, driving a market shift from training-dominant to inference-heavy workloads. This hardware acceleration, combined with strategic open-source adoption and co-designed software, has compressed industrialization timelines from decades to five years while exposing critical bottlenecks in global energy infrastructure and data sovereignty. As the industry navigates an uncharted S-curve of explosive growth, geopolitical competition and alignment risks now define the trajectory toward autonomous, on-device AI integration.
- RAISE Summit20 min
Eric Schmidt: AI and the Genesis of a New Epoch
Dr. Eric Schmidt characterizes the current technological landscape as a new epoch driven by the imminent arrival of reasoning-based AI, predicting that Artificial General Intelligence and superintelligence will emerge within four to six years. The discussion highlights a geopolitical divergence where the United States pursues capital-intensive closed-source models while China leverages open-weight systems, creating a strategic risk where global usage may outpace Western control. Schmidt concludes that massive infrastructure investment in compute capacity will outlast concerns of a market bubble, as autonomous systems will drive unprecedented growth in mathematics and software development independent of human data constraints.
- Milken Institute28 min
A Conversation with the President of Paraguay H.E. Santiago Peña | Global Conference 2025
Under President Santiago Pena's leadership, Paraguay has secured a positive credit outlook from S&P Global and a diversified economy driven by industrial growth and renewable energy exports. The government's strict "no shortcuts" fiscal policy and simplified tax regime have stabilized currency and attracted major foreign investment, particularly from Brazil's manufacturing sector and global tech firms seeking data center connectivity. As the nation pursues OECD membership and expands trade agreements with the EU and UAE, it positions itself as a top-performing Latin American economy with significant potential for green hydrogen and digital infrastructure development.
- Y Combinator27 min
Nobel Laureate John Jumper: AI is Revolutionizing Scientific Discovery
Google DeepMind leader John Jumper presents AlphaFold 2, an AI system that revolutionizes structural biology by accurately predicting protein 3D structures to bridge the massive gap between sequenced genes and experimentally solved forms. The technology's superior accuracy, validated by a thirty-fold reduction in error rates at CASP14 and the release of over 200 million predictions, has accelerated drug discovery and enabled novel applications like re-engineered molecular syringes for targeted therapy. This shift allows experimentalists to advance the pace of biological research by 5 to 10 percent, transforming AI from a narrow computational tool into a fundamental amplifier for scientific discovery.
- Y Combinator39 min
How to Spend Your 20s in the AI Era
The event critically examines how AI is collapsing traditional computer science career safety nets and redefining startup economics by shifting capital formation toward direct revenue generation rather than external validation. It argues that competitive advantage now relies on "forward-deployed engineering" and niche domain expertise, urging founders to build value through tangible utility rather than brand narratives or simulated success. Furthermore, the discussion outlines a preparation framework for entrepreneurs emphasizing frugality, co-founder synchronization, and the strategic use of proprietary data to secure moats in specialized markets before the potential obsolescence of human labor renders current wealth accumulation obsolete.
- Y Combinator35 min
François Chollet: How We Get To AGI
Recent analysis of the Abstraction Reasoning Corpus series reveals that while standard pre-training scaling fails at fluid intelligence, Test-Time Adaptation enables models to dynamically solve novel problems, though current systems still lag significantly behind human performance on the 2025 ARC-2 benchmark. To bridge this gap, the field is adopting the Kaleidoscope Hypothesis, which posits that future architectures must integrate continuous intuition with discrete programmatic reasoning to achieve true compositional generalization. This shift drives the development of endia-like meta-learners capable of synthesizing custom code and maintaining a dynamic library of abstractions, with the explicit goal of accelerating independent scientific discovery by early 2026.
- Y Combinator44 min
Fei-Fei Li: Spatial Intelligence is the Next Frontier in AI
Fei-Fei Li, Diana, Alex, Karl, Yashna, Annie
Dr. Fei-Fei Li, founder and CEO of World Labs, leads a team of renowned technologists to develop spatial intelligence and 3D "world models" as the essential pathway to achieving Artificial General Intelligence. The venture addresses the unique mathematical and physical complexities of reconstructing and generating the three-dimensional world, distinguishing its approach from current language-centric large language models. By combining rigorous data quality standards with a focus on fundamental, interdisciplinary research, the company aims to power next-generation applications ranging from the metaverse to advanced scientific discovery.
- Y Combinator41 min
Satya Nadella: Microsoft's AI Bets, Hyperscaling, Quantum Computing Breakthroughs
Satya Nadella frames the current era as a fourth platform shift driven by AI, cloud infrastructure, and supercomputers, predicting a transition where software engineers evolve into architects managing autonomous agents. He identifies change management as the primary deployment barrier and outlines a strategy where Microsoft utilizes forward deployment engineers to help organizations restructure workflows for "over-constrained" problems in sectors like healthcare and education. Looking ahead, Nadella emphasizes that future growth depends on resolving energy constraints, establishing trust, and developing first-class systems for memory and tool use to maximize social surplus.
- Goldman Sachs24 min
Mid-year outlook: diversify and hedge
Christian Mueller-Glissmann, Alexandra Wilson-Elizondo, Alison Nathan
Goldman Sachs strategists Christian Mueller-Glissman and Alexandra Wilson-Elizondo analyze a complex macro environment where unprecedented volatility in equities, bonds, and the dollar has converged, yet the US economy remains on track for a non-recessionary cool-down. They recommend a shift from traditional diversification toward a "constellation" of alternatives and selective optimism, highlighting opportunities in defensive stocks, European banking, and private capital while warning of elevated summer risks from tariffs and geopolitical tensions. The consensus advice is to embrace growth trajectories while hedging against near-term liquidity thinning, anticipating a market recovery driven by policy clarity and positive fiscal dynamics extending into 2026.
- Y Combinator43 min
Sam Altman: The Future of OpenAI, ChatGPT's Origins, and Building AI Hardware
OpenAI CEO Sam Altman projects that superintelligence will arrive within two decades while declaring the current era the optimal moment to launch companies due to the convergence of reasoning models, falling costs, and new hardware. He outlines a strategy where OpenAI serves as a platform for third-party innovation rather than building all applications, emphasizing the imminent release of powerful open-source models and the integration of AI into robotics and energy infrastructure. Altman further advises founders to prioritize velocity and unique concepts over established pedigrees, warning that the path to success requires immense resilience against skepticism while pursuing radical technological abundance.
- Y Combinator40 min
Andrej Karpathy: Software Is Changing (Again)
The presentation outlines the evolution of software from human-written code to neural network weights and finally to natural language prompts, establishing Large Language Models as a new operating system layer. It details the current infrastructure challenges, cognitive limitations such as hallucination and memory loss, and the strategic shift toward "partial autonomy" systems that maintain human oversight through granular verification loops. Ultimately, the industry faces a transitional decade requiring developers to rewrite existing codebases for agent interaction while managing new risks associated with centralized intelligence infrastructure.
- Milken Institute21 min
Part 1: A Conversation with The Carlyle Group's David M. Rubenstein | Global Conference 2025
David M. Rubenstein, Melissa Stevens
Jefferson Exchange co-founder Jeffrey Rubenstein addresses the critical threats facing U.S. philanthropy, including politicized historical preservation, potential tax policy changes, and declining civic literacy. He advocates for redefining the sector by honoring the percentage of wealth given rather than absolute sums, promoting in-person historical engagement to counter a crisis where nearly all states fail citizenship tests. Furthermore, Rubenstein highlights the strategic value of soft power assets like pandas while emphasizing that the upcoming 250th anniversary should prioritize deep constitutional understanding over superficial celebration.
- Milken Institute27 min
Rebuilding Communities After Disaster with José Andrés & Jennifer Siebel Newsom | Global Conference
José Andrés, Jennifer Siebel Newsom
Following the Los Angeles fires, World Central Kitchen founder José Andrés bypassed bureaucratic hurdles to deploy local restaurants and volunteers, providing immediate nourishment and childcare while revitalizing the affected community's economy. Beyond immediate relief, the organization critiques federal policy gaps by advocating for universal school meals and a dedicated national food security advisor to address long-term hunger and rural instability. This response positions California's integrated disaster model as a blueprint for national resilience, emphasizing that food policy must be central to building a society capable of self-sufficiency.
- Sequoia Capital38 min
OpenAI Codex Team: From Coding Autocomplete to Asynchronous Autonomous Agents
Hanson Wang, Alexander Embiricos, Sonya Huang, Lauren Reeder
OpenAI has rebranded its Codex system into an agentic coding suite specifically RL-tuned to autonomously execute complex enterprise development tasks like debugging, testing, and deployment within isolated cloud environments. Internal adoption data indicates that professional engineers now leverage the tool to generate multiple parallel code iterations daily, effectively shifting their primary responsibility from writing code to validating agent outputs. This strategic pivot aims to redefine 2025 as the "year of agents" by lowering barriers to bespoke software creation while anticipating a market where human developers manage high-level workflows through future interfaces that blend in-IDE pairing with long-running background automation.